Original Article


Black ginseng extract suppresses lung cancer growth in a xenograft mouse model

Hye Jin Park, Ha Rin Namkung, Su Bin Jung, Kwang-Tae Choi, Seung Tae Lee

Abstract

Lung cancer remains a leading cause of cancer-related death, and current therapies are limited by toxicity and drug resistance. Natural product-derived ginsenosides, particularly those in black ginseng extract (BGE), show potent anticancer activity, yet their effects on lung cancer overall are not well understood. Accordingly, we evaluated the preventive and therapeutic potential of BGE on human lung cancer cell proliferation and the growth of solid tumors in mice.

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