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Novel mechanism of immune evasion involving PD-L1 in various cancers

  
@article{TCR10178,
	author = {Keisuke Kataoka and Seishi Ogawa},
	title = {Novel mechanism of immune evasion involving PD-L1 in various cancers},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 4},
	year = {2016},
	keywords = {},
	abstract = {In their editorial, skillfully summarizing major recent findings in the relevant field, Chae’s et al. (1) have made insightful remarks on our article, which demonstrated a unique genetic mechanism for cancer immune evasion through aberrant PD-L1 expression caused by 3'-UTR disruption (2). Initially identified through integrated genetic analysis of adult T-cell leukemia/lymphoma (ATL, 27% of cases) (3), the mechanism was found to operate in a wide variety of common cancer types, including 8% of diffuse large B-cell lymphomas and 2% of stomach adenocarcinomas (2).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/10178}
}