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New insights into the mechanisms of EZH2’s promotion of oncogenesis

   
@article{TCR10500,
	author = {David M. Dorfman and Xuejun Tian},
	title = {New insights into the mechanisms of EZH2’s promotion of oncogenesis},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 6},
	year = {2016},
	keywords = {},
	abstract = {EZH2 is an important enzymatic subunit of the epigenetic regulator polycomb repressive complex 2 (PRC2), which includes EED and SUZ12 subunits. EZH2 functions as a methyltransferase that targets the lysine 27 of histone H3, leading to trimethylation (H3K27me3), a mechanism of post-translational modification that leads to transcriptional repression of PRC2 target genes (1).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/10500}
}