@article{TCR10638,
author = {Marjolein A. Heuvelmans and Matthijs Oudkerk},
title = {Determination of the optimal screen interval in low-dose CT lung cancer screening: are we there yet?},
journal = {Translational Cancer Research},
volume = {5},
number = {Suppl 6},
year = {2016},
keywords = {},
abstract = {In view of the prospective results of the largest randomized controlled lung cancer screening trial worldwide, the National Lung Screening Trial (NLST), and baseline results of other trials, interest in low-dose chest CT for lung cancer screening in high-risk individuals is increasing. In 2011, the U.S. NLST demonstrated that screening using annual low-dose chest CT reduces lung cancer mortality by 15–20% compared to screening by chest radiography (1). This result was translated by several U.S. medical associations, including the U.S. Preventive Services Task Force, into a recommendation to screen subjects at high-risk for developing lung cancer by annual low-dose chest CT (2-5). According to the recommendation of the U.S. Preventive Services Task Force, all individuals between 55 and 80 years old who smoked at least 30 pack-years and quit not longer than 15 years ago are eligible for lung cancer screening. Screening should be discontinued once a person has not smoked for 15 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery (5).},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/10638}
}