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A transcriptional-microRNA network for β-catenin-driven stemness in hepatocellular carcinoma

   
@article{TCR11307,
	author = {William K.K. Wu and Matthew T.V. Chan and Alfred S.L. Cheng},
	title = {A transcriptional-microRNA network for β-catenin-driven stemness in hepatocellular carcinoma},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 7},
	year = {2016},
	keywords = {},
	abstract = {Wnt/β-catenin pathway is important in maintaining stemness of embryonic, adult and cancer stem cells (CSCs) in various organs including liver. However, the mechanisms underlying its deregulation in liver CSCs are poorly understood. Ma and colleagues have recently demonstrated that Oct4/microRNA-1246 signaling axis activates Wnt/β-catenin signaling in a subset of liver CSCs, providing a mechanistic basis for future diagnostic, prognostic and therapeutic developments.},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/11307}
}