@article{TCR11325,
author = {Zhenghong Lee},
title = {[18F]-choline PET/CT as an imaging biomarker for primary liver cancers},
journal = {Translational Cancer Research},
volume = {5},
number = {Suppl 7},
year = {2016},
keywords = {},
abstract = {Choline-based radiotracers were initially developed for prostate cancer imaging (1-4). Comparing to C-11 labeled native choline, the transport efficiency of F-18 labeled fluorinated choline (fluorocholine) is similar, and the substrate specificity of choline kinase, a key enzyme responsible for choline uptake, is also similar towards both for prostate cancer imaging (5). Fluorocholine is labeled with F-18 with a half-life of almost 2 hours for radio-decay, which is long enough for commercial production and dispensing. In addition, fluorocholine with a known dosimetry has comparable safety profile to that of the native choline (6).},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/11325}
}