@article{TCR120211,
author = {Wanli Ye and Yongrui Wang and Hongyan Liu and Yong Jiang and Xingheng Wang and Li Qiu and Yuanjiao Tang},
title = {A comparative analysis of clinical and sonographic features: cutaneous melanoma and melanocytic nevi},
journal = {Translational Cancer Research},
volume = {15},
number = {7},
year = {2026},
keywords = {},
abstract = {Background: Cutaneous melanoma (CM) ranks among the most lethal skin malignancies, with its global incidence rising steadily. Cutaneous melanocytic nevi (CMN), by contrast, are common benign lesions that rarely undergo malignant transformation. Despite their divergent biological behaviors, CM and CMN frequently present with overlapping clinical and ultrasonographic features, rendering preoperative distinction challenging. In this study, we aim to investigate and compare the clinical and sonographic characteristics of CM and CMN.Methods: This retrospective analysis included nine cases of CM, 11 cases of compound nevi, and 22 cases of intradermal nevi, all examined by ultrasound and confirmed by postoperative histopathology. Clinical and sonographic features were compared among the three groups, including gender, age, lesion location, depth, maximum diameter, margin, morphology, hyperechoic spots, posterior acoustic enhancement, lateral acoustic shadow, and color Doppler flow imaging (CDFI) grade. Differences were evaluated between CM and CMN groups, as well as among the three groups.Results: (I) Significant differences (all P},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/120211}
}