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Clinicopathological characteristics and prognosis of breast carcinoma with apocrine differentiation: a propensity score-matched analysis of the SEER database

   
@article{TCR120217,
	author = {Manxiu Li and Liting Jin and Jun Shao and Tiejun Wang and Xinhong Wu},
	title = {Clinicopathological characteristics and prognosis of breast carcinoma with apocrine differentiation: a propensity score-matched analysis of the SEER database},
	journal = {Translational Cancer Research},
	volume = {15},
	number = {7},
	year = {2026},
	keywords = {},
	abstract = {Background: Breast carcinoma with apocrine differentiation (APO) is a rare invasive cancer with unclear prognostic significance. This study compared clinicopathological features and survival outcomes between APO and invasive ductal carcinoma of no special type (IDC-NST).Methods: Data from the Surveillance, Epidemiology, and End Results (SEER) database were analyzed. Propensity score matching (PSM) was used to reduce bias. Overall survival (OS) and breast cancer-specific survival (BCSS) were assessed using Kaplan-Meier (KM) curves and Cox regression. Subgroup analyses were performed by molecular subtypes based on receptor status.Results: APO was associated with older age, higher grade, larger tumors, more lymph node involvement, higher rates of estrogen receptor (ER)/progesterone receptor (PR) negativity and human epidermal growth factor receptor 2 (HER2) positivity, and more frequent chemotherapy use (all P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/120217}
}