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Clinicopathologic correlations of Golgi protein 73 and signal transducer and activator of transcription 3 expression in hepatocellular carcinoma

   
@article{TCR12034,
	author = {Huayu Yang and Haifeng Xu and Yanan Wang and Jinchun Zhang and Xinting Sang and Yilei Mao},
	title = {Clinicopathologic correlations of Golgi protein 73 and signal transducer and activator of transcription 3 expression in hepatocellular carcinoma},
	journal = {Translational Cancer Research},
	volume = {6},
	number = {1},
	year = {2017},
	keywords = {},
	abstract = {Background: To study whether there is correlation between the expressions of Golgi protein 73 (GP73) as well as signal transducer and activator of transcription 3 (STAT3) and the prognosis in hepatocellular carcinoma (HCC) patients. 
Methods: Expression levels of GP73 and STAT3 were assessed in HCC tumor tissues from those who underwent hepatectomy in Peking Union Medical College Hospital. Relationships between clinicopathologic features and GP73/STAT3 protein expression levels were analyzed by Chi-square test. Kaplan–Meier method was employed to evaluate survival, whereas the log-rank test was employed to compare the survival differences between several groups. 
Results: In HCC tumors, the median level of Golgi Protein 73 protein was 4.0 (2.1–5.3) RU, while the median STAT3 protein level was 1.2 (0.4–2.1) RU; both of which were significantly elevated compare to those in normal liver (NL) tissue [1.6 (1.3–2.1) RU, P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/12034}
}