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Is there a role for adjuvant pertuzumab in HER2-positive breast cancer?

   
@article{TCR16369,
	author = {Marco Mazzotta and Maddalena Barba and Laura Pizzuti and Patrizia Vici},
	title = {Is there a role for adjuvant pertuzumab in HER2-positive breast cancer?},
	journal = {Translational Cancer Research},
	volume = {6},
	number = {Suppl 7},
	year = {2017},
	keywords = {},
	abstract = {The outcomes of human epidermal growth factor receptor 2 (HER2)-positive breast cancer was dramatically changed by the introduction of targeted therapies against the HER2 receptor (1).The monoclonal antibody trastuzumab was the first HER2-directed treatment that demonstrated, together with chemotherapy, a significant improvement in treatment outcomes of this subgroup of patients, both in the metastatic (2) and neo-/adjuvant (3-7) settings, thus becoming the mainstay of treatment in HER2 positive breast cancer. The remarkable results achieved led to the development of additional HER2-targeted drugs, raising the hypothesis of a double-HER2 blockade against breast cancer.},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/16369}
}