TY - JOUR AU - de Gooijer, Mark C. AU - Tellingen, Olaf van PY - 2017 TI - Have we considered all barriers to mammalian target of rapamycin inhibition as treatment for diffuse intrinsic pontine glioma? JF - Translational Cancer Research; Vol 6, Supplement 9 (December 14, 2017): Translational Cancer Research Y2 - 2017 KW - N2 - Diffuse intrinsic pontine glioma (DIPG) is a uniformly lethal primary pediatric brain tumor (1,2). Surgical resection is impossible due to its location in the brainstem and invasive nature. Radiotherapy provides just a minor incremental extension in overall survival, whereas chemotherapy is largely ineffective (3-5). There is thus a high unmet need for better therapies. UR - https://tcr.amegroups.org/article/view/17250