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Analysis of prognostic factors, including the incidence of second primary cancer, in patients with early stage laryngeal squamous cell carcinoma treated by radiation-based therapy

   
@article{TCR22472,
	author = {Kaname Sato and Kenichiro Yabuki and Daisuke Sano and Yasuhiro Arai and Yoshihiro Chiba and Teruhiko Tanabe and Goshi Nishimura and Masaharu Hata and Nobuhiko Oridate},
	title = {Analysis of prognostic factors, including the incidence of second primary cancer, in patients with early stage laryngeal squamous cell carcinoma treated by radiation-based therapy},
	journal = {Translational Cancer Research},
	volume = {7},
	number = {4},
	year = {2018},
	keywords = {},
	abstract = {Background: The purpose of this study was to elucidate the efficacy of concurrent chemotherapy and analyze prognostic factors in the radiation-based therapy for early stage laryngeal squamous cell carcinoma (ELSCC).
Methods: The records of 97 patients with ELSCC treated by radiation-based therapy from 2004 to 2016 were retrospectively reviewed. Eighty-one patients were treated with the combined-agent regimens during the treatment. Of the 81 patients, 58 were treated with S-1 regimen and 23 with other regimens. Clinical factors, such as concurrent chemotherapy, non-glottic subsite and the incidence of second primary cancer (SPC) were analyzed for their association with survival.
Results: From the analysis of all patients, the 5-year overall survival (OS) rates were found to be significantly poorer for patients with non-glottic cancer compared to those with glottic cancer (P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/22472}
}