TY  - JOUR
AU  - Xu, Ning
AU  - Wu, Yu-Peng
AU  - Ke, Zhi-Bin
AU  - Liang, Ying-Chun
AU  - Tao, Xuan
AU  - Chen, Shao-Hao
AU  - Li, Xiao-Dong
AU  - Cai, Hai
AU  - Lin, Yun-Zhi
AU  - Lin, Ting-Ting
AU  - Xue, Xue-Yi
PY  - 2019
TI  - Risk factors of developing visceral metastases at diagnosis in prostate cancer patients
JF  - Translational Cancer Research; Vol 8, No 3 (June 29, 2019): Translational Cancer Research
Y2  - 2019
KW  - 
N2  - Background: Risk factors of visceral metastases in prostate cancer (PCa) patients are unclear. The aim of this study is to investigate the risk factors of developing visceral metastases at diagnosis and the impact of these risk factors on the survival of patients with visceral metastatic PCa.  Methods: Patients with visceral metastases at the time of diagnosis of [2010–2015] PCa were identified using the Surveillance, Epidemiology, and End Results (SEER) database. Visceral metastatic distribution data were provided for liver, lung, and brain. The overall survival (OS) was calculated by the Kaplan-Meier method. Multivariable logistic and Cox regression models were performed to identify risk factors and analyze survival outcomes.  Results: A total of 13,092 eligible patients with stage IV PCa were identified from SEER database. A total of 598 patients developed visceral metastases at diagnosis among these patients. In multivariable analyses, patients with PSA >80 ng/mL had 1.545-fold higher risk of developing visceral metastases compared with those with PSA 
UR  - https://tcr.amegroups.org/article/view/29340