@article{TCR34147,
author = {Jie Ning and Yang Jiao and Xuefei Deng and Wei Liu and Xiaoque Xie and Yiyin Zhang and Chenchen Zhao and Tai Ma and Kangsheng Gu},
title = {Correlation between miR-138-5p expression and efficacy of platinum-based chemotherapy in advanced gastric cancer patients},
journal = {Translational Cancer Research},
volume = {9},
number = {1},
year = {2019},
keywords = {},
abstract = {Background: We investigated the relationship between levels of microRNA (miR)-138-5p in plasma and tumor tissues from advanced gastric cancer patients, and the efficacy of first-line platinum-based chemotherapy.
Methods: MiR-138-5p expression was measured by qRT-PCR in cancerous tissues and plasma from 51 advanced gastric cancer patients, in paracancerous tissues and in plasma from healthy volunteers as control. All patients received first-line platinum-based chemotherapy. Correlations between miR-138-5p expression and the treatment efficacy, progression-free survival (PFS), and overall survival (OS) of first-line chemotherapy were evaluated.
Results: Significantly lower levels of miR-138-5p were detected in gastric cancer tissues compared with paracancerous tissues and in the plasma of patients compared with control subjects (both P},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/34147}
}