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Construction of dysregulated long non-coding RNA-associated competing endogenous RNA network in uterine corpus endometrial carcinoma

   
@article{TCR34602,
	author = {Na Li and Peng Mi and Yuanjing Hu},
	title = {Construction of dysregulated long non-coding RNA-associated competing endogenous RNA network in uterine corpus endometrial carcinoma},
	journal = {Translational Cancer Research},
	volume = {9},
	number = {2},
	year = {2020},
	keywords = {},
	abstract = {Background: Competing endogenous RNAs (ceRNAs) render the functions of long non-coding RNAs (lncRNAs) more complicated during cancer processes. Potential lncRNA biomarkers as ceRNAs have not been clearly described for uterine corpus endometrial carcinoma (UCEC). In this research, we researched the functions and regulatory mechanisms of lncRNAs as ceRNAs in UCEC, and their potential applications in prognosis.
Methods: The lncRNAs, mRNAs, and miRNAs expression profiles including 552 UCEC tissues and 35 non-tumor tissues were downloaded from The Cancer Genome Atlas (TCGA) portal. Differentially expressed mRNAs, miRNAs and lncRNAs were confirmed by R/Bioconductor package of edgeR (|log2FC| >2, FDR },
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/34602}
}