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Pertuzumab: a step forward in treating HER2-positive breast cancer

   
@article{TCR377,
	author = {Dimitrios Mavroudis},
	title = {Pertuzumab: a step forward in treating HER2-positive breast cancer},
	journal = {Translational Cancer Research},
	volume = {1},
	number = {2},
	year = {2012},
	keywords = {},
	abstract = {HER2-positive breast cancer represents an aggressive subtype of the disease occurring in approximately 20% of patients. While trastuzumab has revolutionized the treatment of HER2-positive breast cancer, a proportion of patients have de novo trastuzumab-resistant disease and even those who initially respond will eventually develop trastuzumab-resistance. The recent publication in the New England Journal of Medicine of the promising results of the CLEOPATRA trial for the combination of pertuzumab plus trastuzumab plus docetaxel in HER2-positive metastatic breast cancer (MBC) represented a significant advancement in the treatment of this illness (1).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/377}
}