@article{TCR5997,
author = {Kathryn Hitchcock and Michael S. Rutenberg},
title = {Adjuvant radiotherapy for pancreatic cancer: rationale and results},
journal = {Translational Cancer Research},
volume = {4},
number = {6},
year = {2015},
keywords = {},
abstract = {Pancreatic cancer is a highly aggressive disease with a poor prognosis. The mainstay of curative treatment remains surgical resection. Adjuvant chemotherapy has been clearly shown to improve survival. Yet because local-regional recurrence after surgery is the predominant pattern of failure, chemoradiation is often used as a component of treatment. Despite several prospective, randomized trials evaluating adjuvant chemoradiation, controversy persists as to whether it confers a survival benefit. Here we review the rationale for adjuvant chemoradiation and the results of the major studies evaluating the impact of postoperative radiotherapy on disease control and patient survival.},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/5997}
}