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Hyponatremia in small cell lung cancer is associated with a poorer prognosis

   
@article{TCR6481,
	author = {Wenxian Wang and Zhengbo Song and Yiping Zhang},
	title = {Hyponatremia in small cell lung cancer is associated with a poorer prognosis},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Backgrounds: Lung cancer is the leading cause of cancer-related death globally. Small cell lung cancer (SCLC) occurs in 15–20% of lung cancer. Hyponatremia is reported approximately 15% of SCLC. The aim of this retrospective study is to investigate the association between hyponatremia and prognosis of SCLC.
Methods: We retrospectively analyzed data of 631 patients with SCLC from July 2006 to September 2013 in Zhejiang cancer hospital. Overall survival (OS) was calculated with the Kaplan-Meier method. Multivariate regression was performed using the Cox proportional hazards model.
Results: Hyponatremia was present in 16.3% (103/631) of all cases. Severe hyponatremia was detected in 8.1% (51/631). Hyponatremia group was associated with significantly shorter median survival than normal group (all patients: 11.4 vs. 14.5 months, P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/6481}
}