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Radiation, cytokines and T-cell checkpoints: can we cure metastatic cancer?

   
@article{TCR7753,
	author = {Brendan D. Curti},
	title = {Radiation, cytokines and T-cell checkpoints: can we cure metastatic cancer?},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 1},
	year = {2016},
	keywords = {},
	abstract = {Miller et al. discuss the clinical findings of a pilot study investigating the combination of stereotactic body radiation therapy (SBRT) and interleukin-2 (IL-2) in patients with advanced melanoma and renal cancer performed by our group (1). The authors discuss our work in the context of anti-tumor efficacy and toxicity of T-cell checkpoint antibodies including anti-CTLA-4 and anti-PD1. We treated our first patient with SBRT and IL-2 in 2009. There have been remarkable and practice-changing discoveries in cancer immunotherapy since that time summarized in Table 1, and many more are anticipated to follow in the near term.},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/7753}
}