@article{TCR788,
author = {Jacalyn Rosenblatt and David Avigan},
title = {Targetting the PD-L1/PD-1 axis holds promise in the treatment of malignancy},
journal = {Translational Cancer Research},
volume = {1},
number = {4},
year = {2012},
keywords = {},
abstract = {Tumor cells create an immunologic milieu characterized by the disruption of effective antigen presentation, loss of effector cell function and complexity, and upregulation of pathways that promote tolerance and T cell anergy (1,2). A critical element of tumor mediated immunosuppression is the presence of the negative checkpoint molecules CTLA-4 and PDL-1/PD-1 that inhibit immune activation and the expansion of antigen specific T cells (3).},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/788}
}