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Overexpression of cancer cell-derived immunoglobulin G correlates with poor prognosis in gastric cancer patients

  
@article{TCR8033,
	author = {Lin Li and Xiaojing Cheng and Zhixue Zheng and Xiaofang Xing and Xiaohong Wang and Lianhai Zhang and Ting Guo and Hong Du and Ying Hu and Xiaoyan Qiu and Xianzi Wen and Jiafu Ji},
	title = {Overexpression of cancer cell-derived immunoglobulin G correlates with poor prognosis in gastric cancer patients},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Background: Various human epithelial origin cancers produce cytoplasmic immunoglobulin (Ig) G. Recent studies have elucidated that it was related with the tumorigenesis. This study was aimed to identify relationship between the cancer cell-derived IgG expression level and clinical parameters in gastric 
cancer (GC).
Methods: Cancer cell-derived IgG expression was assessed using immunohistochemistry analysis in 231 primary GC tissues. The role of cancer cell-derived IgG on cell proliferation, migration and invasion were assessed.
Results: Our results indicated that IgG was overexpressed in GC tissues (42.2%, 46/109) than in adjacent tissues (11.0%, 12/109, P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/8033}
}