TY - JOUR AU - Inoue, Yusuke AU - Osman, Murat AU - Suda, Takafumi AU - Sugimura, Haruhiko PY - 2016 TI - PD-L1 copy number gains: a predictive biomarker for PD-1/PD-L1 blockade therapy? JF - Translational Cancer Research; Vol 5, Supplement 2 (August 22, 2016): Translational Cancer Research Y2 - 2016 KW - N2 - Immune checkpoint blockade has emerged as a promising and distinct treatment strategy and has caused a paradigm shift in oncology. Significant response and survival benefit have been observed in a fraction of patients who were treated with immune checkpoint inhibitors (ICIs) in several malignancies including melanoma (1-3), non-small-cell lung cancer (NSCLC) (4-7), gastric cancer (8), urothelial carcinoma (9), Hodgkin’s lymphoma (10), and head and neck squamous cell carcinoma (11). UR - https://tcr.amegroups.org/article/view/8810