How to cite item

“Switchable chimeric antigen receptor T cells: a novel universal chimeric antigen receptor platform for a safe control of T-cell activation”

   
@article{TCR8826,
	author = {Silvia Arcangeli and Chiara F. Magnani and Sarah Tettamanti and Ettore Biagi},
	title = {“Switchable chimeric antigen receptor T cells: a novel universal chimeric antigen receptor platform for a safe control of T-cell activation”},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 2},
	year = {2016},
	keywords = {},
	abstract = {In a recent issue of PNAS, Rodgers et al. present an elegant study describing the development of a bifunctional antibody switch able to control retargeting and activation of chimeric antigen receptor (CAR)—engineered T cells, offering a potential additional safety tool compared to standard CAR platforms (1). Indeed, despite the recent striking responses obtained by adoptive transfer of CAR-T cells in relapsed and refractory patients affected by CD19+ malignancies, difficulties have emerged in the ability of controlling both CAR T-cell pharmacokinetic and pharmacodynamic properties (2-6).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/8826}
}