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Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy

   
@article{TCR9016,
	author = {Fabiana Perna and Michel Sadelain},
	title = {Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 2},
	year = {2016},
	keywords = {},
	abstract = {Gardner et al. recently reported on two cases of mixed lineage leukemia (MLL)+ acute myeloid leukemia (AML) occurring after CD19 chimeric antigen receptor (CAR) therapy for MLL+ B-acute lymphoblastic leukemia (ALL) (1). This report provides new insights into mechanisms of immune escape from targeted immunotherapy and strategies to prevent their occurrence with adapted immune interventions.},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/9016}
}