%0 Journal Article %T Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy %A Perna, Fabiana %A Sadelain, Michel %J Translational Cancer Research %D 2016 %B 2016 %9 %! Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy %K %X Gardner et al. recently reported on two cases of mixed lineage leukemia (MLL)+ acute myeloid leukemia (AML) occurring after CD19 chimeric antigen receptor (CAR) therapy for MLL+ B-acute lymphoblastic leukemia (ALL) (1). This report provides new insights into mechanisms of immune escape from targeted immunotherapy and strategies to prevent their occurrence with adapted immune interventions. %U https://tcr.amegroups.org/article/view/9016 %P S221-S225 %@ 2219-6803