How to cite item

Estrogen receptor and human epidermal growth factor receptor-2 quantification and efficacy to trastuzumab

   
@article{TCR9524,
	author = {Paolo Nuciforo},
	title = {Estrogen receptor and human epidermal growth factor receptor-2 quantification and efficacy to trastuzumab},
	journal = {Translational Cancer Research},
	volume = {5},
	number = {Suppl 3},
	year = {2016},
	keywords = {},
	abstract = {Trastuzumab in breast cancer exemplifies the paradigm of successful targeted therapy. This anti-HER2 monoclonal antibody reduces the risk of recurrence by half when combined with standard chemotherapy (1-3). Its target—HER2—is overexpressed in 20% of breast cancers and testing for HER2 positivity is the sine qua non for anti-HER2 therapies. Consensus guidelines have been developed for the definition of HER2-positive (HER2+) tumors. HER2 protein expression has to be 3+ by immunohistochemistry (IHC) or the gene has to be amplified by fluorescence (FISH) or chromogenic (CISH) in situ hybridization (4).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/9524}
}