This focused issue of Translational Cancer Research is guest-edited by Umberto Malapelle from Department of Public Health, University of Naples Federico II, Naples, Italy and Dr. Christian Rolfo from Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA
Papers published in the issue represent a critical point of view on well-established therapeutic options and new perspectives in the very complex field of NSCLC patients management with also an interesting focus on communicational issues in the precision medicine era, to support the oncologist to select the best therapeutic approach for advanced NSCLC patients.