Erratum: LncRNA CASC9 regulates cell proliferation, apoptosis and cell cycle via sponging miR-145-5p in colon cancer cells

Erratum to: Transl Cancer Res 2019;8:2769-80.

In the published article entitled “LncRNA CASC9 regulates cell proliferation, apoptosis and cell cycle via sponging miR-145-5p in colon cancer cells” (1), Figure 2, Figure 3A,3B and Figure 5A-5D were published incorrectly. The updated versions of Figure 2, Figure 3A,3B and Figure 5A-5D are provided below.

Figure 2 The effects of lncRNA CASC9 knockdown on cell proliferation in colon cancer cells. (A,B) Images of cells colonies in HCT116 cells (A) and SW480 cells (B) captured by camera in the left. The relative colony (diameter >0.5 mm) formation rates counted by Image J software v.1.48 is shown in the right charts. (C,D) Western blotting analysis of expression levels of Ki-67, PCNA in HCT116 and SW480 cells. **P<0.001 vs. Blank; ^##P<0.001 vs. siNC. Blank, transfection with nothing; siNC, non-specific negative control siRNA; siCASC9, siRNA for CASC9.

Figure 3 The effect of lncRNA CASC9 knockdown on cell apoptosis and cycle in colon cancer cells. (A,B) Flow cytometry analysis shows the cell apoptosis of HCT116 cells (A) and SW480 cells (B). The apoptosis rates are shown in the right. (C,D) The cell cycle of HCT116 cells (C) and SW480 cells (D) measured by flow cytometry. The proportions of cells with G0/G1, S and G2/M were counted in the right. **P<0.001 vs. Blank, ^##P<0.001 vs. siNC. Blank, transfection with nothing; siNC, non-specific negative control siRNA; siCASC9, siRNA for CASC9.

Figure 5 LncRNA CASC9 regulates the cell colony formation ability, cell apoptosis and cell cycle through targeting miR-145-5p in colon cancer cells. (A,B) Images of cells colonies in HCT116 cells (A) and SW480 cells (B). The relative colony formation rates counted by Image J software is shown in the right. The pictures were took by a camera. Colonies (diameter >0.5 mm) were counted by Image J software v.1.48. (C,D) The cell apoptosis of HCT116 cells (C) and SW480 cells (D) measured by flow cytometry. The apoptosis rates are shown in the right. (E,F) Flow cytometry analysis for cell cycle of HCT116 cells (E) and SW480 cells (F). **P<0.001 vs. IC, ^##P<0.001 vs. I. Blank, transfection with nothing; siNC, non-specific negative control siRNA; siCASC9, siRNA for CASC9. CASC9-WT, cells transfected with CASC9-WT luciferase reporter; CASC9-MUT, cells transfected with CASC9-MUT luciferase reporter; IC, inhibitor control; I, miR-145-5p inhibitor; siCASC9+I, co-transfection with siCASC9 and miR-145-5p inhibitor.

This correction does not affect the results, statistical analyses, interpretation of the data, or the main conclusions of the study. The authors have also double checked the other figures and found no further errors. This correction has been confirmed by authors Guangyuan Sun, Fei Guo, Xueliang Wu, and Lei Han. Author Jun Xue could not be reached for confirmation due to loss of contact.

The authors apologize for this oversight and any confusion that may have caused.

Click here to view the updated version of the article.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

References

1. Sun G, Guo F, Wu X, et al. LncRNA CASC9 regulates cell proliferation, apoptosis and cell cycle via sponging miR-145-5p in colon cancer cells. Transl Cancer Res 2019;8:2769-80. [Crossref] [PubMed]