How do the QUARTZ trial results inform future research for patients with brain metastases from non-small cell lung cancer?

We read with interest the editorial by Tsao (1), and thank the author for this well considered response to our recent paper describing the results of the QUARTZ trial of whole brain radiotherapy for patients with inoperable brain metastases from non-small cell lung cancer (2). We continue to be encouraged by the amount of discussion taking place surrounding treatment options for these patients.