Preface

In the context of cancer treatment, radiotherapy plays an important role as more than 50% of cancer patients receive radiotherapy as part of multimodal treatment of their disease. Radiotherapy can be delivered percutaneously, interventionally e.g., as brachytherapy or during surgery as intraoperative radiotherapy (IORT). IORT is increasingly used for different entities as it delivers targeted radiotherapy to the tumor bed immediately during surgery. In the early 20th century the first reported IORT was delivered in a patient with endometrial cancer. Later a series of IORT was reported from Japan, where a 60Co source was used to provide IORT.