Hot topics in cholangiocarcinoma

Cholangiocarcinoma (CC) comprises a heterogeneous group of epithelial cancers emerging at any level from the biliary tree. CC is classified into intrahepatic (iCC) and extrahepatic (eCC), based on anatomical tumor location (1). The main points of interest of this topic include the changes in epidemiological assessment, alternative therapeutic options and the advent of new target treatments that may modify the therapeutic algorithm of CC patients.