Potential value of immunoscoring in rectal cancer patients

Rectal cancer therapy has markedly changed during the past decades with clear improvements for the patients (1). Population-based data based on registries with high validity (2,3) show that local recurrence rates can be as low as about 5% (4,5), similar to that in dedicated centers. Multidisciplinary team discussions prior to therapy initiation have likely also contributed to the improvements (5,6).