Editorial

Clinical translation of predictive markers for anti-EGFR monoclonal antibody therapy in metastatic colorectal cancer

Andrew Rowland, Christos S. Karapetis, Arduino A. Mangoni, Michael D. Wiese, Ganessan Kichenadasse, Ross A. McKinnon, Michael J. Sorich

Abstract

Altered function of the epidermal growth factor receptor (EGFR) and associated mitogen-activated protein (MAP) kinase pathway plays a key role in disease progression in metastatic colorectal cancer (mCRC).

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