The driving role of cancer-testis genes: a new perspective for cancer researches

We appreciate the attention Kaczkowski et al. paid to our previous work (1), in which we provided a source of candidate epi-driver genes by studying the cancer-testis (CT) gene expression pattern in normal and tumor tissues. The identification of CT genes and the link between CT genes and cancer epi-drivers are attractive but less-studied topics. We believe that the study of CT genes with special expression patterns provides new perspectives for the identification of cancer epi-drivers.