Vol 14, No 7 (July 30, 2025): Translational Cancer Research

Editorial Commentary

Metabolomic profiling for predicting breast cancer treatment toxicities
Jennifer J. Hu, Alexandra N. McMahon, Yawen Lu, Veronica Z. Paley
Translational Cancer Research  
2025;
14
(7)
:3883-3886
.
 (30 July 2025) 
PDF Full Text (287) Peer Review File COI Form Open Access Get Permission
First-line therapy for recurrent metastatic head and neck squamous cell carcinoma: every rose has its thorn
Dena Hasan, J. Chad Brenner, Paul L. Swiecicki, Molly E. Heft Neal
Translational Cancer Research  
2025;
14
(7)
:3887-3891
.
 (30 July 2025) 
PDF Full Text (317) Peer Review File COI Form Open Access Get Permission
Limitations and oncological uncertainties of intraductal laser ablation for pathological nipple discharge
Mariam Rizk, Kefah Mokbel
Translational Cancer Research  
2025;
14
(7)
:3892-3893
.
 (30 July 2025) 
PDF Full Text (169) Peer Review File COI Form Open Access Get Permission
Unlocking the future of immunotherapy with circulating tumor DNA (ctDNA)-based liquid biopsy in non-small cell lung cancer
Bartłomiej Tomasik, Bartosz Kamil Sobocki
Translational Cancer Research  
2025;
14
(7)
:3894-3898
.
 (30 July 2025) 
PDF Full Text (240) Peer Review File COI Form Open Access Get Permission
Women’s hormonal health research and care: the times, they are a-changin’
Jennifer D. Merrill, Lawrence M. Nelson
Translational Cancer Research  
2025;
14
(7)
:3899-3904
.
 (30 July 2025) 
PDF Full Text (193) Peer Review File COI Form Open Access Get Permission

Original Article

TC2N promotes the proliferation and invasion of head and neck cancer cells with the p53-R175H
Qian Zhang, Xiaogang Zhou, Xianglin Hao, Qi Sun, Gang Zhang, Shuai Xu
Translational Cancer Research  
2025;
14
(7)
:3905-3919
.
 (30 July 2025) 
PDF Full Text (374) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Integrative single-cell and bulk transcriptomic analyses identify a robust four-gene signature for risk stratification in neuroblastoma
Zhanbo Wu, Ningning Sun, Yinan Dong, Li Zhang, Jifeng Sun, Xin Li, Runmei Li
Translational Cancer Research  
2025;
14
(7)
:3920-3929
.
 (30 July 2025) 
PDF Full Text (312) Reporting Checklist Peer Review File COI Form Open Access Get Permission
The incidence, risk factors, and survival of acute myeloid leukemia secondary to chronic myelomonocytic leukemia: a population-based study
Wenshuai Zheng, Yanchao Liang, Jijia Zheng, Zirui Zhu, Zongze Wu, Lixun Guan
Translational Cancer Research  
2025;
14
(7)
:3930-3942
.
 (30 July 2025) 
PDF Full Text (294) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification and validation of hub genes for kidney renal clear cell carcinoma treated with metformin and everolimus combination therapy
Shenbao He, Bin Zhang, Lili Zhang, Panfeng Shang, Zhongjin Yue
Translational Cancer Research  
2025;
14
(7)
:3943-3960
.
 (30 July 2025) 
PDF Full Text (282) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
First-line treatment of extensive-stage small cell lung cancer with immune checkpoint inhibitors acting on different targets: a systematic review and network meta-analysis
Meng Li, Yu-Zhu Chen, Da-Zhong Chen, Yang Wang, Hong-Li Zhao
Translational Cancer Research  
2025;
14
(7)
:3961-3972
.
 (30 July 2025) 
PDF Full Text (389) Reporting Checklist Peer Review File COI Form Open Access Get Permission
IL-6 promotes metastasis and EMT of non-small cell lung cancer cells by up-regulating FGL1 via STAT3 pathway
Jing Liu, Qiuge Liu, Wenjing Qian, Chengguo Zong, Ruoyu Wang
Translational Cancer Research  
2025;
14
(7)
:3973-3990
.
 (30 July 2025) 
PDF Full Text (369) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
A novel fumaric acid metabolism-related prognostic signature associated with prognosis and immune infiltration landscape in laryngeal squamous cell carcinoma
Zhang Feng, Yuhang Yang, Jinqing Li, Long Zuo, Meijiao Duan, Bingmin Xu, Zhenlian Xie, Dongzhi Zuo, Xiaosong He, Fangxian Liu, Feng He
Translational Cancer Research  
2025;
14
(7)
:3991-4008
.
 (30 July 2025) 
PDF Full Text (328) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Stemness-hypoxia genes PPARGC1A, PFKFB3, and SLC2A5 are associated with prognosis and tumor immune microenvironment in hepatocellular carcinoma
Dan Wang, Ruotian Wang, Yuewen Zhang, Zhitao Li, Hong Zheng, Wanggang Xu
Translational Cancer Research  
2025;
14
(7)
:4009-4023
.
 (30 July 2025) 
PDF Full Text (300) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Maximal resection for malignant scalp tumors: is it valuable for long-term follow-up?
Yangbai Sun, Xuesi Liu, Qingrong Ye, Qinyuan Zhu, Chunmeng Wang, Wangjun Yan
Translational Cancer Research  
2025;
14
(7)
:4024-4033
.
 (30 July 2025) 
PDF Full Text (246) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Downregulation of ANKRD22 and its prognostic significance in squamous cell carcinoma of the cervix: a bioinformatics analysis based on public datasets
Hyung-Joon Yoon, Eun Taeg Kim, Changho Song
Translational Cancer Research  
2025;
14
(7)
:4034-4045
.
 (30 July 2025) 
PDF Full Text (260) Reporting Checklist Peer Review File COI Form Open Access Get Permission
TSPAN9 inhibits malignant progression of hepatocellular carcinoma
Li Xu, Buyun Yan, Zhaonv Yao, Yansong Hu, Yuhua Chen, Di Li, Cheng Lin, Shengkui Tan, Xiaonian Zhu
Translational Cancer Research  
2025;
14
(7)
:4046-4057
.
 (30 July 2025) 
PDF Full Text (223) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Integrative analysis of CRISPR screening and gene expression data identifies a three-gene prognostic model associated with immune microenvironment in neuroblastoma
Xin Li, Wanrong Li, Jian Wang
Translational Cancer Research  
2025;
14
(7)
:4058-4070
.
 (30 July 2025) 
PDF Full Text (225) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Association between real-time shear wave elastography findings and HER-2 expression in breast cancer
Ying He, Qi Zhang, Yuwei Zeng, Danni Zhu, Jienv Lou, Dan Mao
Translational Cancer Research  
2025;
14
(7)
:4071-4079
.
 (30 July 2025) 
PDF Full Text (231) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Integrating single-cell and bulk RNA sequencing data to construct a pyroptosis-related prognostic signature and analyze the tumor microenvironment in gastric cancer
Ruiyu Wang, Shu Huang, Ping Wang, Rui Luo, Yizhou Wang, Xiaomin Shi, Wei Zhang, Lei Shi, Xian Zhou, Xiaowei Tang
Translational Cancer Research  
2025;
14
(7)
:4080-4099
.
 (30 July 2025) 
PDF Full Text (274) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Clinical value of SPP1 overexpression in patients with papillary thyroid carcinoma
Linfeng Xin, Changqing Li, Hui Ni, Guangcheng Fu, Qin Qin, Lin Zhang
Translational Cancer Research  
2025;
14
(7)
:4100-4114
.
 (30 July 2025) 
PDF Full Text (223) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Development of a quantitative genomic instability scoring system and a related competing endogenous RNA network in head and neck squamous cell carcinoma
Wei Li, Fangqin Yu, Mingwei Wang, Xiguo Liu, Zhidan Mei
Translational Cancer Research  
2025;
14
(7)
:4115-4141
.
 (30 July 2025) 
PDF Full Text (208) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Survival outcomes of local versus radical resection for appendiceal neuroendocrine tumors: a population-based study
Xia Ren, Fuli Gao, Ganhong Wang, Jian Chen, Luojie Liu
Translational Cancer Research  
2025;
14
(7)
:4142-4159
.
 (30 July 2025) 
PDF Full Text (114) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Construction and validation of an anoikis-related long non-coding RNA-based prognostic model for head and neck squamous cell carcinoma
Sijie Yuan, Ziyu Zhai, Yixu Wang, Jilin Peng, Yinghui Ding, Kun Zhao, Xiaodan Zhu, Yuan Zhang, Ling Li, Fanglei Ye, Le Wang
Translational Cancer Research  
2025;
14
(7)
:4160-4178
.
 (30 July 2025) 
PDF Full Text (190) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Prognostic implications of store-operated calcium entry signatures and immune dynamics in neuroblastoma via machine learning
Wanrong Li, Xin Li, Jian Wang
Translational Cancer Research  
2025;
14
(7)
:4179-4193
.
 (30 July 2025) 
PDF Full Text (188) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification and validation of a novel signature based on M2 macrophage co-expressed genes in bladder cancer
Xinyu Xu, Minyu Yan, Zhiwen Xie, Yongqing Zhang, Lei Wu, Bimeng Zhang, Juntao Jiang
Translational Cancer Research  
2025;
14
(7)
:4194-4207
.
 (30 July 2025) 
PDF Full Text (169) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Development and validation of machine learning models for classifying cancer-related sarcopenia using Kinect-based mixed-reality exercises in breast cancer survivors
Byunggul Lim, Wook Song
Translational Cancer Research  
2025;
14
(7)
:4208-4218
.
 (30 July 2025) 
PDF Full Text (287) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Development of a prognostic model based on m6A reader HNRNPA2B1 upregulation and immune infiltration in multiple malignant tumors
Yang Han, Wei Xia, Zhong-Na Ma, Zhong-Chao Mai, Yu-Shui Ma, Da Fu, Juhua Zhuang
Translational Cancer Research  
2025;
14
(7)
:4219-4242
.
 (30 July 2025) 
PDF Full Text (274) Reporting Checklist Peer Review File COI Form Open Access Get Permission
A comparison of hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma: a bioinformatics analysis
Yiwen Huang, Guangpeng Chen, Hong Fan, Shangzi Wang, Huangbo Yuan, Zhengqiu Liu, Tiejun Zhang
Translational Cancer Research  
2025;
14
(7)
:4243-4259
.
 (30 July 2025) 
PDF Full Text (190) Peer Review File COI Form Open Access Get Permission
Clinical pathological characteristics correlation of H3F3A gene mutation in giant cell tumor of bone: a study of 96 cases
Juan Du, Siying Liu, Lei Miao, Huijun Yang, Jiayao Li, Fei Wang, Xuzhi Wang, Ningning Shen, Zhiqing Yang, Lifang Gao, Wenxia Ma, Chen Wang
Translational Cancer Research  
2025;
14
(7)
:4260-4278
.
 (30 July 2025) 
PDF Full Text (284) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Correlation between the decreased expression of NUDT18 and tumor progression in endometrial cancer
Yue Hua, Mengdan Miao, Yan Wang, Huaijun Zhou
Translational Cancer Research  
2025;
14
(7)
:4279-4292
.
 (30 July 2025) 
PDF Full Text (195) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Nicotine-induced PD-L1 expression in lung squamous cell carcinoma is mediated by the α7-nAChR/STAT3 signaling pathway
Yinan Li, Wenting Wang, Yaoyao Wang, Ce Zhou, Xin Zou, Yixuan Wang, Ning Wang
Translational Cancer Research  
2025;
14
(7)
:4293-4304
.
 (30 July 2025) 
PDF Full Text (273) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
A nine-gene signature with potential targets for predicting the prognosis of patients with esophageal cancer
Mengfei Sun, Yandi Ma, Fuqiang Zhou, Quansheng Xiang, Shangfeng He, Jie Yu, Wenjie Wang, Jingwen Qi, Yang Wang, Qi Sun, Hui Li, Yunzhao Chen, Xiaobin Cui
Translational Cancer Research  
2025;
14
(7)
:4305-4320
.
 (30 July 2025) 
PDF Full Text (267) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Efficacy of transcatheter arterial chemoembolization-based multimodal treatment in patients with neuroendocrine tumors involving the liver
Hu Xu, Li Zhang, Juan Zhang, Yi Chen, Ningling Ge, Yuhong Gan, Rongxin Chen, Maopei Chen
Translational Cancer Research  
2025;
14
(7)
:4321-4330
.
 (30 July 2025) 
PDF Full Text (201) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Construction and validation of an EGFR-related risk signature identified SHC1 as a prognostic biomarker for lung adenocarcinoma
Hanqin Cao, Bohao Sun, Jing Wang, Shanshan Wu, Na Shi, Jing Zhang, Yichen Wu, Hao Wang
Translational Cancer Research  
2025;
14
(7)
:4331-4347
.
 (30 July 2025) 
PDF Full Text (212) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Efficacy of second- and third-line chemotherapy after chemotherapy with platinum doublet and immunotherapy in non-small cell lung cancer: a descriptive study
Martin Svaton, Miloslav Marel, Ondrej Venclicek, Juraj Kultan, Marketa Cernovska, Michal Hrnciarik, Jana Krejci, Karel Odrazka, Petr Domecky
Translational Cancer Research  
2025;
14
(7)
:4348-4356
.
 (30 July 2025) 
PDF Full Text (336) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
miR-490-5p inhibits the progression of osteosarcoma by targeting HDAC2
Huiqun Jiang, Jiahao Xia, Yuan Tao, Yu Zhang
Translational Cancer Research  
2025;
14
(7)
:4357-4368
.
 (30 July 2025) 
PDF Full Text (160) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
The safety and efficacy of NEPA in preventing postoperative nausea and vomiting after general anesthesia during gastrointestinal cancer surgery: a single-center retrospective study
Yinchao Zhang, Chao Li, Linze Xu, Jin Zhang, Dandan Wu, Yu Bai, Huikai Li
Translational Cancer Research  
2025;
14
(7)
:4369-4380
.
 (30 July 2025) 
PDF Full Text (269) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Most eligible candidates for primary tumor resection among metastatic colorectal cancer patients: a SEER-based population analysis
Cheng-Wu Jin, Sun-Yuan Lv, Can Yang, Mao Tan, Vishal G. Shelat, Peter C. Ambe, Timothy Price, Li Song, Wei Peng, Shu-Lang Jian, Heng Liu
Translational Cancer Research  
2025;
14
(7)
:4381-4398
.
 (30 July 2025) 
PDF Full Text (222) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Development and validation of a Hypoxia and Lactate Metabolism Prognostic Score (HLMPS) for breast cancer using machine learning
Zhou Fang, Shichong Liao, Zhong Wang, Juanjuan Li, Lijun Wang, Yimin Zhang, Yueyue Guo, Feng Yao
Translational Cancer Research  
2025;
14
(7)
:4399-4415
.
 (30 July 2025) 
PDF Full Text (238) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Family resilience and related influencing factors in Chinese patients with malignant spinal tumors: a cross-sectional study
Liuqing Cao, Leiting Gu, Lijuan Xu, Lifeng Yao, Daniele Vanni, Zhenqi Lu, Li Chen, Xiaoju Zhang
Translational Cancer Research  
2025;
14
(7)
:4416-4428
.
 (30 July 2025) 
PDF Full Text (244) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Identification and validation of anoikis-related differentially expressed genes in nasopharyngeal carcinoma
Chaobin Huang, Ying Peng, Xueping Zheng, Siqian Cai, Zhongmei Lin, Yahan Zheng, Wei Zheng, Fengying Peng, Yuanji Xu
Translational Cancer Research  
2025;
14
(7)
:4429-4446
.
 (30 July 2025) 
PDF Full Text (240) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Classification and influencing factors of family resilience and posttraumatic growth in patients with spinal tumor: a cross-sectional study
Di Hu, Qian Ma, Lifeng Yao, Xiaoju Zhang, Lijuan Xu, Li Chen
Translational Cancer Research  
2025;
14
(7)
:4447-4460
.
 (30 July 2025) 
PDF Full Text (212) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission

Review Article

Impact of smoking on the effectiveness of different non-small-cell lung cancer therapies
Kairui Yang
Translational Cancer Research  
2025;
14
(7)
:4461-4473
.
 (30 July 2025) 
PDF Full Text (433) Reporting Checklist Peer Review File COI Form Open Access Get Permission

Erratum

Erratum: Long non-coding RNA SNHG17 promotes gastric cancer progression by inhibiting P15 and P16
Editorial Office
Translational Cancer Research  
2025;
14
(7)
:4474-4475
.
 (30 July 2025) 
PDF Full Text (98) Open Access Get Permission
Erratum: PA-MSHA exerts potent activity against cetuximab-resistant colorectal cancer through the miR-7-5p/Akt3/Wnt-β-catenin pathway
Editorial Office
Translational Cancer Research  
2025;
14
(7)
:4476-4478
.
 (30 July 2025) 
PDF Full Text (114) Open Access Get Permission