Erratum: LncRNA HEIH modulates the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the miR-193a-5p/CDK8 axis

Erratum to: Transl Cancer Res 2024;13:423-36.

In the published article entitled “LncRNA HEIH modulates the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the miR-193a-5p/CDK8 axis” (Transl Cancer Res 2024;13:423-36; doi: 10.21037/tcr-23-2228) (1), Figures 2D,4D,6A,6D were published incorrectly. The updated versions of Figures 2D,4D,6A,6D are provided below. This correction does not affect the conclusions of this article.

Figure 2 Silencing HEIH suppressed the proliferation, migration, and invasion of HCC cells. (A) The transfection efficiency of Hep3B and sk-Hep-1 cells was assessed by qRT-PCR; (B) cell viability was measured by MTT assays; (C) a wound-healing analysis was conducted to measure the migration of Hep3B and sk-Hep-1 cells (scar bar =100 µm, ×200); (D) the invasion of Hep3B and sk-Hep-1 cells was detected by transwell assays (crystal violet staining, scar bar =100 μm, ×400). (E) the tumor weights of the mice were quantified at 4 weeks post-injection; (F) the growth curves of the xenograft tumors were drawn by the tumor volume at 4 weeks post-injection. *, P<0.05 and **, P<0.01 vs. si-NC. HEIH, high expression in hepatocellular carcinoma; HCC, hepatocellular carcinoma; qRT-PCR, quantitative real-time polymerase chain reaction; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide.

Figure 4 MiR-193a-5p overexpression suppressed proliferation, migration, and invasion in HCC cells. (A) MiR-193a-5p expression in the transfected Hep3B and sk-Hep-1 cells; (B) cell viability was assessed by MTT assays; (C) migration was measured by wound-healing assays (scar bar =100 μm, ×200); (D) invasion was detected by transwell assays (crystal violet staining, scar bar =100 μm, ×400). **, P<0.01 vs. Blank (A) or miR-NC (B-D). miR-193a-5p, microRNA 193a-5p; HCC, hepatocellular carcinoma; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide.

Figure 6 HEIH regulated the proliferation, migration and invasion of the HCC cells via miR-193a-5p/CDK8 axis. (A) Protein expression of CDK8 was detected by Western blot; (B) cell viability was determined by MTT assays; (C,D) migration and invasion were assessed by wound-healing (scar bar =100 µm, ×200) and a transwell assays (crystal violet staining, scar bar =100 µm, ×400). *, P<0.05 and **, P<0.01 vs. miR-NC + pcDNA-NC; ^#, P<0.05 vs. miR-193a-5p mimics + pcDNA-NC. miR-193a-5p, microRNA 193a-5p; CDK8, cyclin-dependent kinase 8; HEIH, high expression in hepatocellular carcinoma; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide; HCC, hepatocellular carcinoma.

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References

1. Huang Y, Li D, Lu L, et al. LncRNA HEIH modulates the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the miR-193a-5p/CDK8 axis. Transl Cancer Res 2024;13:423-36. [Crossref] [PubMed]