Vol 14, No 10 (October 31, 2025): Translational Cancer Research

Original Article

Identification of the immune subtypes associated with the prognosis and immunotherapy of metastatic melanoma
Feng Zhang, Xiaodong Zhang, Huanzhong Su, Longcheng Hong, Yuhui Wu, Chang Shu
Translational Cancer Research  
2025;
14
(10)
:6136-6151
.
Identification and validation of an immune-related programmed cell death signature for predicting prognosis and immunotherapy in large-scale multicenter cohorts for lung adenocarcinoma
Zhetao Li, Chuyun Fu, Jie Chen, Wenbo Ji, Zaiqi Ma
Translational Cancer Research  
2025;
14
(10)
:6152-6171
.
Identification and validation of RAS signaling-related genes for prognostic prediction and immunological characterization in gastric cancer
Jinhong Cao, Jun Liu, Lingling Ye, Xiaojuan Zheng
Translational Cancer Research  
2025;
14
(10)
:6172-6194
.
The timing of surgery for elderly patients with locally advanced breast cancer
Jiameng Liu, Hehui Mao, Zijie Wu, Wei Zhuang, Yiyin Weng, Juli Lin, Jujiang Guo, Zhipeng Hua
Translational Cancer Research  
2025;
14
(10)
:6195-6206
.
Cervical cancer molecular subtype identification and prognosis classification by a metabolism-related gene expression
Xiaohong Chen, Caixia Hong, Guohui Zhang, Bixian Lin, Jingyi Liu, Ronglong Wang, Chunbo Li
Translational Cancer Research  
2025;
14
(10)
:6207-6221
.
Epidemiological and clinicopathologic characteristics, and prognostic factors of patients with extra-skeletal osteosarcoma: a Surveillance, Epidemiology, and End Results population study
Zhenzhong Liu, Fapeng Gao, Li Du, Zheng Liu
Translational Cancer Research  
2025;
14
(10)
:6222-6240
.
Predictive factors for clinical outcome of palliative ventriculoperitoneal shunt in the treatment of leptomeningeal metastasis
Lingzhao Min, Ningning Zhang, Qing Zhang, Mingzhe Zheng, Yiqian Zhu
Translational Cancer Research  
2025;
14
(10)
:6241-6247
.
Identification of lysine crotonylation-driven molecular clusters and immune dysregulation in HBV-related hepatocellular carcinoma via bioinformatics and machine learning
Jinlian Li, Linbin Huang, Baoren He, He Xie, Qunying Wu, Limin Chen
Translational Cancer Research  
2025;
14
(10)
:6248-6268
.
Transcriptomics combined with in vitro experimental validation probes polyamine metabolic profiles in low-grade gliomas
Linfeng Pan, Huili Chen, Xinyu Zhang, Jing Zhang, Chaoqun Lian
Translational Cancer Research  
2025;
14
(10)
:6269-6288
.
Ultrasound and immunohistochemical predictors of neoadjuvant chemotherapy response in breast cancer
Yanqiang Ma, Yangyang Zhu, Jiali Zhu, Fang Nie
Translational Cancer Research  
2025;
14
(10)
:6289-6299
.
Development and validation of nomograms predicting survival in operable breast cancer patients at reproductive age after breast conserving surgery and postoperative radiotherapy based on SEER database
Sirui Zhu, Ke Zhang, Wei Lu, Huaiyu Yang, Chenxuan Yang, Changyuan Guo, Lei Guo, Xuemin Xue, Zhongzhao Wang, Lixue Xuan
Translational Cancer Research  
2025;
14
(10)
:6300-6315
.
Identification of cancer-associated fibroblast subpopulation and construction of an immunotherapy signature for gastric cancer
Kunqin Wang, Dong Xue, Chao Yin, Guanghui Wang
Translational Cancer Research  
2025;
14
(10)
:6316-6329
.
Integration of single-cell and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of sodium overload-induced cell death in lung adenocarcinoma
Yilun Shi, Xiangyu Qu, Dayu Liu, Huihong Zhang, Suchen Wang, Jiarui Song, Li Wang, Wenrui Wang
Translational Cancer Research  
2025;
14
(10)
:6330-6347
.
Integrative analysis of polo-like kinase family identifies a prognostic signature and validates PLK2 as a therapeutic target in glioma
Chengjun Zheng, Qiaodong Chen, Zheng Fang, Delong Zhang, Yutong Feng, Shuqing Yu, Ying Zhang, Zhaoshi Bao
Translational Cancer Research  
2025;
14
(10)
:6348-6363
.
Prognostic significance of key immune cell functional alterations in clear cell renal cell carcinoma
Yuhai Wu, Yantao Zhang, Ke Sun, Wenjie Niu, Yanhui Mei, Shimiao Zhu, Changyi Quan
Translational Cancer Research  
2025;
14
(10)
:6364-6387
.
Comparative microbiome profiling reveals unique signatures in multiple primary lung cancers
Yun Chen, Yang Wang, Shuai Shen, Jiagui Lu, Qihui Peng, Xiangyun Yan, Hao Peng, Zheyuan Xu
Translational Cancer Research  
2025;
14
(10)
:6388-6402
.
PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma: a retrospective cohort study
Mingming Tang, Qingwen Chen, Xinjiang Xu, Zihao Zhang, Liang Han, Hao Wu
Translational Cancer Research  
2025;
14
(10)
:6403-6413
.
CCT4 as a prognostic biomarker correlated with immune infiltration and hepatocyte dedifferentiation in hepatocellular carcinoma
Xinglin Zhang, Peirong Li, Hongbo Zhao
Translational Cancer Research  
2025;
14
(10)
:6414-6428
.
Anti-ovarian cancer effects of forsythiaside A: insights from in vitro and in vivo studies
Haocheng Guan, Yongchao Li, Menglong Xu, Wenqiang Sun, Ruijun Shi, Shuwei Li
Translational Cancer Research  
2025;
14
(10)
:6429-6441
.
A pentacyclic triterpene tormentic acid inhibits the proliferation and migration of pancreatic ductal adenocarcinoma cells
Mohammed Merae Alshahrani, Ahmed Abdullah Al Awadh
Translational Cancer Research  
2025;
14
(10)
:6442-6453
.
shRNA-based PD-1 suppression preserves memory phenotype and function of CD19-targeted CAR-T cell
Jiaxuan Zhao, Han Wu, Zhe Sun, Yeting Cui, Nan Liu, Yixuan Wang, Youyong Wang, Jiangzhou Shi, Tongcun Zhang
Translational Cancer Research  
2025;
14
(10)
:6454-6468
.
Unveiling PIK3CA mutation: a prognostic beacon in endometrial carcinoma and its immune implications
Shuai Cao, Yucheng Zhao, Lu Zhang, Junhong Zhuang, Peiqi Jia, Dongmei Han, Hao Jin, Liming Xu
Translational Cancer Research  
2025;
14
(10)
:6469-6482
.
Methylation-regulated tumor suppressor gene HOXB4 inhibits human lung adenocarcinoma A549 cell invasion and metastasis through the RAP1 signaling pathway
Lingxiang Zhang, Zhong Xu, Shu Wu, Yamen ahmed Muad, Weiyan Peng, Lin Ye
Translational Cancer Research  
2025;
14
(10)
:6483-6496
.
The role of cancer stem cells in the progression of colorectal cancer and the tumor microenvironment: new perspectives from single-cell RNA sequencing and spatial transcriptomics analyses
Yuting Wu, Xianglin Liu, Wenqiang Liu, Qingliang Jiang, Yangyang Li, Hengyu Li, Liqiang Hao
Translational Cancer Research  
2025;
14
(10)
:6497-6519
.
KRT23 promotes proliferation invasion and metastasis of gastric cancer through epithelial-mesenchymal transition mediated by the PI3K/AKT/mTOR signaling pathway
Yi Xie, Fanghui Zhou, Xuelian Li, Pailan Peng
Translational Cancer Research  
2025;
14
(10)
:6520-6535
.
B7 homolog 6 promotes the killing activity of natural killer cells against cervical cancer through the downstream ERK pathway of NKp30
Ruimeng Guo, Ou Chai, Changying Li, Yanying Xu, Xuewang Guo
Translational Cancer Research  
2025;
14
(10)
:6536-6550
.
LINC01314 suppresses proliferation and invasion via epithelial-to-mesenchymal transition regulation in lung adenocarcinoma
Wen Zhu, Xue Pan, Anyuan Zhong, Yongkang Huang, Minhua Shi
Translational Cancer Research  
2025;
14
(10)
:6551-6564
.
Development and validation of a prognostic prediction model for gastric cancer based on lipophagy-related genes
Laibijiang Wusiman, Dingding Song, Alimu Tulahong, Abulajiang Abudukelimu, Juan Liu, Xuying Wei, Shu He, Wenbin Zhang
Translational Cancer Research  
2025;
14
(10)
:6565-6587
.
Bioinformatics analysis identifies ULK3 as a novel prognostic and immune-related biomarker in esophageal cancer
Kai Cui, Jinxi He, Nan Zhao, Rong Ma, Yanyang Wang
Translational Cancer Research  
2025;
14
(10)
:6588-6604
.
Development and validation of a nomogram comprising GLUT1 and clinical characteristics for predicting overall survival in intrahepatic cholangiocarcinoma
Li-Ping Gong, Yulan Weng, Jing Zhou, Xiangqi Huang, Jian-Ning Chen, Dan He, Yi-Wang Zhang, Yongmei Cui, Jing Liang, Chun-Kui Shao
Translational Cancer Research  
2025;
14
(10)
:6605-6617
.
Integrative analysis of the potential of DISP3 as a biomarker for thyroid cancer
Chenghui Lu, Xufu Wang
Translational Cancer Research  
2025;
14
(10)
:6618-6636
.
Liriopesides B inhibits proliferation and metastasis and induces apoptosis of oral squamous cell carcinoma via the PI3K/Akt/mTOR signaling pathway
Jinzhi Wei, Hejia Guo, Binghua Feng, Wei Lv, Xiaoping Su, Cuiping Li, Xuanping Huang
Translational Cancer Research  
2025;
14
(10)
:6637-6652
.
Intratumoral disulfidptosis heterogeneity in triple-negative breast cancer, a multiomics integration analysis
Zi-Xian Dong, Yang Ou-Yang, Lan Fang, Xiao-Qing Song
Translational Cancer Research  
2025;
14
(10)
:6653-6666
.
TIPE3 promotes breast cancer progression and metastasis via the AKT-GSK3β-β-catenin/Snail pathway
Yiling Bai, Jing Wu, Dongmei Yu, Qiang Li, Yan Li, Yufeng Xie
Translational Cancer Research  
2025;
14
(10)
:6667-6680
.
Multi-omics analysis reveals intratumoral microbiota as modulators of the immune environment within thyroid cancer
Zihao Liang, Jie Gao, Qin Zheng
Translational Cancer Research  
2025;
14
(10)
:6681-6693
.
Prognostic prediction nomogram of elderly patients with metastasis colon cancer and distant metastasis pattern: a SEER database analysis
Xing Luo, Jincheng Tang, Wei Peng, Fang Liu
Translational Cancer Research  
2025;
14
(10)
:6694-6708
.
Machine learning models for predicting survival in patients of hepatocellular carcinoma with second primary malignancy
Yu Nie, Lu Nie, Boyu Li, Yuanyuan Wang, Liyuan Wang, Xingyan Lv, Runjie Sun, Mengting Xia, Ruiyang Wang, Xing Cui
Translational Cancer Research  
2025;
14
(10)
:6709-6722
.
Integrative analysis identified THBS1 as a key prognostic biomarker with therapeutic vulnerability in patients with laryngeal cancer
Shaokun Huang, Xuan Shan, Fan Song, Min Wu, Chaofan Li, Xiaohui Wang, Ruiping Zhao, Juan Ye
Translational Cancer Research  
2025;
14
(10)
:6723-6737
.
Construction and verification of a prognostic model for cervical cancer based on genes associated with the p53 regulatory pathway
Zhaoming Wu, Jing Zhang, Bohao Sun, Yichen Wu, Nan Wang, Changqing Li
Translational Cancer Research  
2025;
14
(10)
:6738-6757
.
Unveiling critical genes and molecular subtypes in ovarian cancer: insights into tumor immunity and carbohydrate-lipid metabolism
Yuxuan Zhang, Wei Zhang, Wenli Xie, Xiangyu Wang, Ping Wei
Translational Cancer Research  
2025;
14
(10)
:6758-6770
.
Integrated multi-omic analysis unravels the characteristics of the metabolism-related intratumoral microbes and establishes a novel signature for predicting prognosis and therapeutic response in lung adenocarcinoma
Huan Liu, Yueguang Liu, Yixuan Dai, Lei Zhang, Mei Long
Translational Cancer Research  
2025;
14
(10)
:6771-6790
.
Decoding the genomic landscape of adenoid cystic carcinoma: a retrospective cohort study of MYB family alterations, NOTCH pathway activation, and clinical outcomes
Jun Wu, Xi Zhao, Yi-Xuan Liu, Ting-Yao Ma, Yue Zhao, Guo-Liang Yang, Xiao-Hong Chen
Translational Cancer Research  
2025;
14
(10)
:6791-6802
.
Single-cell analysis revealed a diagnostic model of hepatocellular carcinoma based on cancer stem cell-related gene
Yang Ding, Qi Liang, Songbo Ma, Jia Yang, Zengrui Ma, Zhiqi Yang, Baoding Li
Translational Cancer Research  
2025;
14
(10)
:6803-6813
.
Role of 18F-FDG PET/CT in the diagnosis and treatment response assessment of primary pulmonary lymphoma
Yongzhu Pu, Ran Xie, Kun Li, Chunhong Zhang, Sheng Zhao, Xin Liu, Haicheng He, Ningning Chen, Yuqiang Xiao, Qiuyuan Hu, Zhiyong Deng, Long Chen
Translational Cancer Research  
2025;
14
(10)
:6814-6833
.
CC/CXC chemokine risk signature at single-cell resolution: a machine learning model for precision stratification in cervical cancer
Bing Xu, Xinyan Shi, Yanfei Liu, Lyuping Xu, Qingxue Zhou
Translational Cancer Research  
2025;
14
(10)
:6834-6848
.
Identification of PDGFRB as a prognostic immune-related biomarker in gastric cancer through bioinformatics and clinical analysis
Shujing Wang, Bo Meng, Yuanan Liu, Qiang Wu
Translational Cancer Research  
2025;
14
(10)
:6849-6863
.
NSD2 mediates NF-κB and matrix metalloproteinases to drive hepatocellular carcinoma malignant progression
Meng Xiong, Qianshan Ding, Yingjie Wu, Muhammad Jamal, Xingruo Zeng, Yufei Lei, Hengjing He, Di Xiao, Qiuping Zhang, Liang Shao, Xiaoxing Huang, Xinran Li
Translational Cancer Research  
2025;
14
(10)
:6864-6880
.
Molecular dynamics simulation and single-cell and spatial transcriptomics validate immune and prognostic biomarkers in colorectal cancer and construct a clinical prognostic model
Xuanting Chen, Yuan Zhou, Hongyu Li, Wang Guo, Songqi Li, Zhen Zhang, Qiang Tang
Translational Cancer Research  
2025;
14
(10)
:6881-6906
.
Study of non-surgical therapeutic patterns and prognosis in elderly patients with stage II non-small-cell lung cancer: an investigational study based on the SEER database
Lixia Zhang, Xin Xu, Yunbin Gao
Translational Cancer Research  
2025;
14
(10)
:6907-6918
.
TOP2A promotes non-small cell lung cancer progression via LDHA-mediated glycolysis and histone lactylation
Qiong Wu, Ye Fan, Weiqin Wang, Feng Hu
Translational Cancer Research  
2025;
14
(10)
:6919-6939
.
Identification of prognostic genes associated with sphingosine-1-phosphate in gastric cancer to construct a risk mode
Jing Han, Lan Lei, Jiangfeng Wang
Translational Cancer Research  
2025;
14
(10)
:6940-6959
.
Development and verification of risk prediction nomograms for overall and specific mortality in primary small bowel cancer: a population-based study
Yingxiang Wu, Wen Luo
Translational Cancer Research  
2025;
14
(10)
:6960-6974
.
ATP citrate lyase (ACLY) promotes the occurrence of gastric cancer through regulating lipid metabolism
Sijia Zhang, Yihuang Liu, Xia Zhang, Nailin Zhang, Jianhui Sun, Pingping Chen
Translational Cancer Research  
2025;
14
(10)
:6975-6989
.
Development and validation of a machine learning-based prognostic model using mitochondrial dysfunction-related genes for colorectal cancer patients
Chang Liu, Yaxuan Li, Jiaxu Song, Yijing Zhao
Translational Cancer Research  
2025;
14
(10)
:6990-7006
.
Prognostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography metabolic parameters combined with serum apolipoprotein A1 in patients with diffuse large B-cell lymphoma: a clinical study
Zhengong Jia, Lin Liu, Weipeng Li, Hui Li, Shujie Ge, Yongquan Hu
Translational Cancer Research  
2025;
14
(10)
:7007-7017
.
A novel prognostic tool for triple-negative breast cancer: creating and testing a parthanatos-related gene model
Zitong Yang, Siyi Chen, Jiahong Sun, Guangmin Wu, Delu Mu, Jiandong Wang
Translational Cancer Research  
2025;
14
(10)
:7018-7036
.
Development and validation of a machine learning model for predicting 3-year overall survival in metastatic nasopharyngeal carcinoma: a SEER database and web visualization study
Lei Qiu, Yinjiao Fei, Yuchen Zhu, Kexin Shi, Jinling Yuan, Gefei Jiang, Xingjian Sun, Yuandong Cao, Weilin Xu, Shu Zhou
Translational Cancer Research  
2025;
14
(10)
:7037-7052
.
A novel disulfidptosis-related lncRNAs index to predict prognosis and therapeutic target in hepatocellular carcinoma
Xun-Feng Gao, Xiao-Lu Xu, Jin-Hui Zhang, Heng Zhang, Li-Quan Cai, Feng Gao, Jin-Long Zhang, Dan Yu, Qin-Wen Tai
Translational Cancer Research  
2025;
14
(10)
:7053-7070
.
Constructing an immune-related prognostic model and exploring the function of HMGB3, TNFSF4, and CORO2A in breast cancer
Meng Tang, Tingting Huang, Wei Zhang, Chi Wang, Rui Pan, Yaqin Zhao
Translational Cancer Research  
2025;
14
(10)
:7071-7088
.
Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma
Hongyu Xie, Shenling Liao, Libo Liang, Ga Liao
Translational Cancer Research  
2025;
14
(10)
:7089-7101
.
Efficacy, safety and cost-effectiveness of chemo-immunotherapy combinations for recurrent or metastatic nasopharyngeal carcinoma: an updated systematic review and cost-effectiveness analysis
Lei Qiu, Qiran Wei, Yachun Hu, Jinling Yuan, Mengxing Wu, Yurong Li, Yuting Xu, Xin Guan, Yuandong Cao, Juan Pu, Zhou Ding, Yinjiao Fei, Weilin Xu, Shu Zhou
Translational Cancer Research  
2025;
14
(10)
:7102-7118
.
Integrative single-cell and bulk transcriptomes analyses reveal T cell-related prognostic risk model and tumor immune microenvironment modulation in colorectal cancer
Ping Liu, Yizhou Wang, Shu Huang, Rui Luo, Ruiheng Xie, Jieyv Peng, Ruiyu Wang, Ping Wang, Xiaomin Shi, Wei Zhang, Lei Shi, Xian Zhou, Xiaowei Tang
Translational Cancer Research  
2025;
14
(10)
:7119-7135
.
Identification of molecular subtypes for breast cancer based on butyrate metabolism-related genes to assess prognosis and immune landscape
Huitao Yao, Xiuping Hu, Jiazhen Feng, Lunan Tan
Translational Cancer Research  
2025;
14
(10)
:7136-7156
.
RNA sequencing and bioinformatics analysis have identified MAST1 as a potential biomarker and therapeutic target for cervical cancer
Zhijia Xie, Tao Shen, Yuhong Wang, Ruyue Ma, Hong Xu, Ruirui Zhang, Hailan Su
Translational Cancer Research  
2025;
14
(10)
:7157-7169
.
Clinical significance of CD155 expression and correlation with immune cell infiltration in triple-negative breast cancer
Yan Zhao, Jinlu Wang, Tongjun Sun, Sijuan Jiang, Zongyu Xie, Jingru Lai, Ganyu Sang, Xin Jin
Translational Cancer Research  
2025;
14
(10)
:7170-7185
.
Epidemiological characteristics and prognostic factors of high-grade brainstem glioma for all ages and the establishment of a nomogram
Bowen Huang, Ting Liu, Hongfei Li, Xiang Li, Gonggong Lu, Jiuhong Li
Translational Cancer Research  
2025;
14
(10)
:7186-7198
.
A deep learning-based prognostic prediction model for distal cholangiocarcinoma incorporating the metabolism-inflammation marker monocyte-to-high-density lipoprotein cholesterol ratio
Hai-Bin Zhang, Xiao-Ting Han, Lian Wang
Translational Cancer Research  
2025;
14
(10)
:7199-7213
.
Exploration of efferocytosis-related genes as potential therapeutic targets in endometrial cancer
Huiping Zhang, Man Di, Shan Wang, Mingming Wei, Mingxia Jia, Zhuo Zhou
Translational Cancer Research  
2025;
14
(10)
:7214-7228
.
FBXO5 drives hepatocellular carcinoma progression and is a target for tea polyphenol-mediated inhibition
Xinyu Wang, Dandan Yang, Jiao Wang, Zheng Huang, Junjie Gao, Jun Xia, Yingjie Zhang, Jia Ma, Xueshan Pan
Translational Cancer Research  
2025;
14
(10)
:7229-7244
.
Ferroptosis-associated RNA-binding proteins predict clinical outcomes in head and neck squamous cell carcinoma
Ming Liu, Zhiyu Zhang, Lei Shi, Guanggang Shi
Translational Cancer Research  
2025;
14
(10)
:7245-7255
.
Deciphering immune landscapes: an ICD-lncRNA-derived prognostic signature for pancreatic adenocarcinoma
Hao Zhu, Xiaojie Gan, Danyang Shen, Ding Sun
Translational Cancer Research  
2025;
14
(10)
:7256-7276
.
Immune-related long noncoding RNAs in predicting the prognosis and immune landscape of intrahepatic cholangiocarcinoma: a bioinformatics analysis with experimental verification
Gao Huang, Yuan-Shu Lian, Wen-Ting He, Fang Xiao, Wen-Bo Zou
Translational Cancer Research  
2025;
14
(10)
:7277-7290
.
The role of liquid-liquid phase separation in hepatocellular carcinoma: single-cell analysis and identification of prognostic biomarkers
Wenjie Lei, Rui Luo, Xiaohong Wang, Xiaomin Shi, Jieyu Peng, Qi Chen, Shiqi Li, Wei Zhang, Lei Shi, Yan Peng, Shu Huang, Xiaowei Tang
Translational Cancer Research  
2025;
14
(10)
:7291-7310
.
A novel manganese metabolism- and immune-related prognostic risk model for acute myeloid leukemia
Lin Guo, Yue Cao, Wei-Ying Gu, Yan Lin
Translational Cancer Research  
2025;
14
(10)
:7311-7328
.
Radiomics-based machine learning for glioma grade classification: a multicenter study with SHapley Additive exPlanations interpretability analysis
Yumeng Shi, Wei Jiang, Li Zhou, Yu Shi, Xinran Ji, Wenjie Zheng, Hongyu Zhao, Ninghua Yao
Translational Cancer Research  
2025;
14
(10)
:7329-7346
.
The systemic immune-inflammation index in the efficacy prediction of neoadjuvant chemotherapy in patients with endometrial cancer
Jing Lin, Lingli Gu, Filomena Marino Carvalho, Luigi Della Corte, Jie Dang
Translational Cancer Research  
2025;
14
(10)
:7347-7357
.
CXCR3 enhanced murine chimeric antigen receptor T cells in the treatment of solid tumors
Xiangzhi Zhang, Luyu Zhu, Qiang Wang, Qinggang Xu, Xiaoyan Wang, Feng Yu
Translational Cancer Research  
2025;
14
(10)
:7358-7373
.
A diagnostic test evaluation: dynamic optical functional imaging system for early-stage breast cancer detection
Xiangming He, Linyin Fan, Jian Huang, Xiping Zhang, Naohiro Ishii, Xiaojia Wang, John Zhang
Translational Cancer Research  
2025;
14
(10)
:7374-7386
.
Bulk and single-cell transcriptomics of stomach adenocarcinoma provide prognostic insights via the application of a novel gene signature associated with manganese metabolism
Dou Li, Dan Wei, Lianyong Li, Changqing Zhong, Xinwei Bao, Wenjuan Zhang, Xinke Sui
Translational Cancer Research  
2025;
14
(10)
:7387-7399
.
CST7+ macrophages/monocytes in melanoma: single-cell insights into immunotherapy response
Kaitao Yao, Fan Wu, Daiwei Liu, Boying Zheng, Jing Li, Yang Liu, Li Wang, Liuqing Zheng, Zhanlin Li, Gang Zhou
Translational Cancer Research  
2025;
14
(10)
:7400-7418
.
The association of geriatric nutritional risk and perioperative anesthesia–related adverse reactions in elderly patients with colorectal cancer—a prospective study
Xiaofeng You, Yangxiuzi Xu, Jingxuan Zhao, Jacopo Crippa, Aaron C. Lim, Zoltan H. Nemeth, Feiyue Zhang
Translational Cancer Research  
2025;
14
(10)
:7419-7427
.

Review Article

Advances and challenges in circulating tumor DNA-based early detection of lung cancer
Jung-Ki Yoon, Ji Young Park, Yeon Wook Kim, Hyung-Joo Oh, Young-Chul Kim
Translational Cancer Research  
2025;
14
(10)
:7428-7437
.
A narrative literature review on the clinical utility of activated partial thromboplastin time and anti-factor Xa activity assays in cancer patients with anticoagulant therapy
Hai-Xin Li, Li-Hong Song, Yan-Hong Chen, Jie Zhao, Xiao-Fang Zhang
Translational Cancer Research  
2025;
14
(10)
:7438-7449
.