Vol 5, Supplement 7 (December 29, 2016): Translational Cancer Research

Editorial

Urachal carcinoma: towards a precision medicine
Alessia Mennitto, Claudio Vernieri, Giuseppe Procopio
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1307-S1310
.
Different intellectual outcomes in molecular subgroups of medulloblastoma
Noriyuki Kijima, Yonehiro Kanemura
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1311-S1314
.
Indolence versus aggression in non-small cell lung cancer: defining heterogeneity to impact clinical outcomes
Brandon S. Grimes, Kostyantyn Krysan, Linh M. Tran, Stacy J. Park, Denise R. Aberle, Avrum E. Spira, Steven M. Dubinett
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1315-S1319
.
Should optimal supportive care alone be the standard of care for brain metastases patients from non-small cell lung cancer, who are not eligible for radiosurgery or surgery?
May N. Tsao
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1320-S1322
.
BRAF inhibitors in advanced BRAF-positive non-small cell lung cancer
Tiziana Vavalà
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1323-S1327
.
Cell intrinsic PD-1 checkpoint blockade releases the brake on human chimeric antigen receptor (CAR) T cells for solid tumors
Joseph A. Fraietta, J. Joseph Melenhorst, Bruce L. Levine
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1328-S1332
.
Personalized peptide vaccine in prostate cancer: capitalizing on existing immunity
Ravi A. Madan, James L. Gulley
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1333-S1335
.
Simplicity is complexity resolved”: the case of postoperative radiation therapy after breast conservation
Pierfrancesco Franco, Gary M. Freedman, Umberto Ricardi, Philip Poortmans
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1336-S1339
.
Emerging multikinase inhibitors for the treatment of differentiated thyroid cancer: whom to treat?
Jolanta Krajewska, Dagmara Rusinek, Barbara Jarzab
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1340-S1344
.
Routine prophylactic drainage in rectal surgery—closing the chapter?
Martine A. Frouws, Cornelis J. H. van de Velde
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1345-S1348
.
Tumor treating fields—effective, but at what cost?
Isabella Zhang, Jonathan P. S. Knisely
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1349-S1353
.
A cytological link between radioresistance and autophagy
Kuan-Chih Chow
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1354-S1357
.
Hypoxia-induced DNA hypermethylation: another reason to normalize tumor vessels
Mei Rosa Ng, Rakesh K. Jain
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1358-S1362
.
Relapsed small cell lung cancer: is more better?
Vinicius Ernani, Apar Kishor Ganti
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1363-S1365
.
JMJD3 histone demethylase—a potential therapeutic target for metastatic hepatocellular carcinoma?
Sai-Kam Li, Yick Pang Ching
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1366-S1368
.
Is combined chemotherapy with cisplatin, etoposide and irinotecan the new standard treatment for patients with sensitive relapsed small cell lung cancer?
Alessandro Morabito
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1369-S1371
.
Hypofractionated radiotherapy for breast cancer: how to evaluate chronic toxicity and cosmesis?
Javier Sanz, Nuria Rodríguez, Manuel Algara
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1372-S1376
.
Sentinel node biopsy in combination with extended pelvic lymph node dissection for men with prostate cancer at risk of nodal involvement
Mauro Gacci, Pietro Spatafora, Sergio Serni
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1377-S1379
.
Omission of adjuvant radiotherapy in early-stage breast cancer: have we identified a subgroup?
Angela Lin
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1380-S1382
.
Trunk or branch? Identifying and targeting intratumoral heterogeneity in hepatocellular carcinoma using genomics and patient derived primary cancer cells
Kelsey E. Wuensch, Aik Choon Tan
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1383-S1386
.
Micropapillary urothelial carcinoma: is molecular hair-splitting on target?
Nuzhat Husain, Azfar Neyaz
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1387-S1392
.
Distinct benefit from crizotinib in lung cancer patients carrying distinct ALK translocations: is fluorescent hybridization in situ testing still sufficient to guide clinical decisions?
Natalia V. Mitiushkina, Evgeny N. Imyanitov
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1393-S1395
.
PD-L1 is a diverse molecule regulating both tumor-intrinsic signaling and adaptive immunosuppression
Kim A. Brogden, Shireen Vali, Taher Abbasi
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1396-S1399
.
Transgenic mouse models of Idh-mutated neural stem cells: an appropriate model for low grade glioma?
William Leenders
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1400-S1403
.
Pelvic drain after colorectal anastomosis: useful or useless
Varut Lohsiriwat
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1404-S1407
.
A transcriptional-microRNA network for β-catenin-driven stemness in hepatocellular carcinoma
William K.K. Wu, Matthew T.V. Chan, Alfred S.L. Cheng
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1408-S1412
.
Adding chemotherapy to TKI: can we improve first-line treatment for EGFR-mutated NSCLC patients?
Francesco Passiglia, Antonio Russo
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1413-S1416
.

Commentary

Predictive biomarkers for prostate brachytherapy—not there yet
Jaimee C. Eckers, Randall J. Kimple
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1417-S1419
.
PGC1α curtails prostate cancer metastasis via metabolic rewiring
Erica J. McDonald, Vanessa S. Arciero, Urban Emmenegger
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1420-S1423
.
How far have we achieved by systemic therapy for recurrent/metastatic nasopharyngeal carcinoma?
Victor Lee
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1424-S1427
.
A new approach to high risk pediatric acute lymphoblastic leukemia?
Diane Hanna, Mary Ann Anderson
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1428-S1432
.
When tumors are (co-)opting to resist anti-angiogenic treatment
Lasse D. Jensen
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1433-S1436
.
Versikine, a proteolysis product of Versican: novel therapeutics for multiple myeloma
Nidhi Gupta, Raman Kumar, Alpana Sharma
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1437-S1439
.
The role of long noncoding RNA FOXF1-AS1 as a tumor suppressor in non-small cell lung cancer
Hao Zheng, Aswini R. Krishnan, Angela E. Zou, Weg M. Ongkeko
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1440-S1442
.
Checkpoints inhibitors in first line therapy of metastatic non-small cell lung cancer patients
Luis E. Raez, Christian Rolfo, Mauricio Mahave, Christian Caglevic
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1443-S1448
.
Trimming the fat in non-small cell lung cancer: a new small molecule inhibitor of acetyl-CoA carboxylase to target fatty acid synthesis
Amanda L. Davis, Steven J. Kridel
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1449-S1452
.
Repurposing multiple sclerosis drug dimethyl fumarate, a promising fast track candidate for systemic cutaneous T cell lymphoma treatment
Martin Herold, Luisa Klotz
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1453-S1456
.
The Wnt/β-catenin pathway is activated by miR-1246 in liver cancer stem cells
Melanie A. Eshelman, Gregory S. Yochum
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1457-S1460
.
Targeting B-Raf kinase for thyroid cancer treatment: promise and challenge
Xiulong Xu, Richard A. Prinz
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1461-S1464
.
Toward the clarification of the role of whole-brain radiation therapy for brain metastases from non-small cell lung cancer: a comment about the QUARTZ trial
Hirotake Saito, Toshimichi Nakano, Miki Shioi, Hidefumi Aoyama
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1465-S1468
.
Utility of gene expression signature in treatment decision of breast cancer
Seema Thakur, Ankan Mukherjee Das, Bhudev C. Das
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1469-S1472
.
Major thoracic surgery in patients under antiplatelet therapy
Francesco Cassiano, Cecilia Menna, Claudio Andreetti, Mohsen Ibrahim
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1473-S1475
.
Empiric H. pylori therapy—10-day concomitant, bismuth quadruple or 14-day triple therapy: none is best
Yoshio Yamaoka, David Y. Graham
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1476-S1478
.
miRNA transported by exosomes: a key machinery in tumor microenvironment mediated chemoresistance
Teresa Gagliano, Thomas Simon, Georgios Giamas
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1479-S1482
.
Rac1 and EMT: a dangerous liaison?
Javier Vaquero, Laura Fouassier
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1483-S1485
.
Secreted reporter proteins, a valuable complementary tool for non-invasive preclinical monitoring of brain tumour growth
Ludwig J. Dubois, Frank Verhaegen, Marc A. Vooijs
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1486-S1488
.
[18F]-choline PET/CT as an imaging biomarker for primary liver cancers
Zhenghong Lee
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1489-S1492
.
Direct acting antivirals for hepatitis c and hepatocellular carcinoma recurrence: an unsolved mystery
Virginia A. Dines, Michael D. Leise
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1493-S1495
.

Perspective

Perspective on the regulatory role of UGT2B28 as a conjugating enzyme in the progression of prostate cancer
Therina du Toit, Amanda C. Swart
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1496-S1502
.
HIF-pathway proteins: central regulators of tumor immunology
Sundary Sormendi, Ben Wielockx
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1503-S1508
.
Small molecule inhibition of speckle-type POZ protein-substrate interactions for the treatment of renal cell carcinoma
Byung Joon Hwang, Yun Kee
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1509-S1514
.
Tumor intrinsic resistance to anti-programmed death 1
Jacqueline Liu, Ting Fang, Adil I. Daud
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1515-S1520
.
Transoral endoscopic thyroidectomy: current state of the art—a systematic literature review and results of a bi-center study
Thomas Wilhelm, Guoyang Wu, Afshin Teymoortash, Christian Güldner, Thomas Günzel, Stefan Hoch
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1521-S1530
.
DNA hypermethylation of tumor suppressor genes as an early lung cancer biomarker
Tomasz Powrózek, Teresa Małecka-Massalska
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1531-S1538
.
Evolving concepts of micropapillary variant urothelial carcinoma
M. Francesca Monn, Liang Cheng
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1539-S1542
.
Programmed death ligand 1 expression and human papillomavirus status: penile cancer prognostic factors and new therapeutic opportunities
Kelly L. Stratton, Mohammad Ramadan, Ahmed Eldefrawy, Daniel J. Culkin
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1543-S1545
.

Correspondence

Response letter: “epigenetic modulation of a miR-296-5p:HMGA1 axis regulates Sox2 expression and glioblastoma stem cells”
Hernando Lopez-Bertoni, John Laterra
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1546-S1548
.
Why observational studies are important in comparative effectiveness research: the effect of breast-conserving therapy and mastectomy in the real world
Marissa C. van Maaren, Philip Poortmans, Luc J. A. Strobbe, Linda de Munck, Sabine Siesling
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1549-S1550
.
DDR1 and Notch: a multifaceted synergy
Chiara Ambrogio, David Santamaría
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1551-S1553
.
Response letter: Bronchial sleeve resection or pneumonectomy for non-small cell lung cancer? Pneumonectomy is still a valid choice
Saana Andersson, Ilkka Ilonen, Jarmo A. Salo, Jari Räsänen
Translational Cancer Research  
2016;
5
(Suppl 7)
:S1554-S1555
.

Disclosure:

This supplement was published without any sponsorship or funding.