Vol 14, No 3 (March 30, 2025): Translational Cancer Research

Editorial Commentary

The predictive value of HER2DX assay with pathological response and prognosis in patients with early HER2-positive breast cancers: commentary on the PHERGain trial
Tasuku Matsuoka, Yurie Yamamoto, Masakazu Yashiro
Translational Cancer Research  
2025;
14
(3)
:1507-1510
.
Circulating tumor cell-based PSMA and PSA expression as a predictive and prognostic tool in prostate cancer
Panagiotis J. Vlachostergios
Translational Cancer Research  
2025;
14
(3)
:1511-1515
.

Original Article

Development and validation of a prediction model based on two-dimensional dose distribution maps fused with computed tomography images for noninvasive prediction of radiochemotherapy resistance in non-small cell lung cancer
Min Zhang, Ya Li, Yong Hu, Bo Du, Youlong Mo, Tianchu He, Yang Yang, Benlan Li, Ji Xia, Zhongjun Huang, Fangyang Lu, Bing Lu, Jie Peng
Translational Cancer Research  
2025;
14
(3)
:1516-1530
.
Targeting PAR-2-driven inflammatory pathways in colorectal cancer: mechanistic insights from atorvastatin and rosuvastatin treatment in cell line models
Rajashree Patnaik, Riah Lee Varghese, Sara Khan, Bintul Huda, Farida Bhurka, Layla Amiri, Yajnavalka Banerjee
Translational Cancer Research  
2025;
14
(3)
:1531-1566
.
Oncologic and obstetric outcomes of a novel nerve-sparing radical trachelectomy while preserving the uterine branches of the pelvic nerves
Kentaro Nakayama, Sultana Razia, Tomoka Ishibashi, Hitomi Yamashita, Kosuke Kanno, Masako Ishikawa, Seiya Sato, Haruo Takeshita, Satoru Kyo
Translational Cancer Research  
2025;
14
(3)
:1567-1575
.
Risk factors, prognostic factors and nomograms for distant metastasis in colorectal neuroendocrine neoplasms: a SEER-based study
Yuqin Bai, Na Lei, Pan Zhang, Qian Yang, Fei Feng, Yue Zhao
Translational Cancer Research  
2025;
14
(3)
:1576-1595
.
Prediction of visceral pleural invasion of clinical stage IA lung adenocarcinoma based on computed tomography features
Deng Lyu, Yun Wang, Wenting Tu, Su Hu, Yanqing Ma, Xiuxiu Zhou, Yi Xiao, Rongbo Dong, Li Fan, Shiyuan Liu
Translational Cancer Research  
2025;
14
(3)
:1596-1608
.
Incidence, clinical features, and survival outcomes of primary malignant conjunctival tumor: a US population-based retrospective cohort analysis based on the SEER database (1975–2018)
Lin-Feng He, Shi-Yi Tang, Yu-Jiao Wang, Yun Zhang, Sheng-Mei Huang, Xiao-Jing Huang
Translational Cancer Research  
2025;
14
(3)
:1609-1625
.
Small peritoneal macrophages are accelerators of peritoneal metastasis of colorectal cancer
Wanli Yang, Feng Jiang, Lixia Xu, Nan Pang, Chao Yang, Ruihua Yu, Haiqun Chen
Translational Cancer Research  
2025;
14
(3)
:1626-1637
.
Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway
Mei Hong, Hao Zhu, Weikang Liu, Pengyu Zhang, Song Yu, Quangen Gao, Genhai Shen, Bin Li, Gang Wang
Translational Cancer Research  
2025;
14
(3)
:1638-1650
.
Development and validation of nomograms for predicting the prognosis of colorectal cancer patients
Yingqi An, Jianping Gong, Aitang Xiao
Translational Cancer Research  
2025;
14
(3)
:1651-1663
.
Triage of women with positive HPV: comparing DNA ploidy analysis with HPV 16/18 genotyping and cervical cytology
Wei Song, Lan Zhu, Min Zheng, Hua Liu
Translational Cancer Research  
2025;
14
(3)
:1664-1674
.
Comprehensive analysis of molecular characteristics between primary and breast-derived metastatic ovarian cancer
Junqi Long, Bo Liu, Jinmeng Li, Xinchan Ji, Nian Zhu, Xujie Zhuang, Huina Wang, Lujia Li, Yuhaoran Chen, Xiaohui Li, Shuangtao Zhao
Translational Cancer Research  
2025;
14
(3)
:1675-1690
.
Comparative survival analysis of stage T1-T2N0M0 lung squamous cell carcinoma and adenocarcinoma using SEER data, and nomogram analysis for early-stage lung squamous cell carcinoma
Chang Liu, Cheng Fang, Dan Shen
Translational Cancer Research  
2025;
14
(3)
:1691-1709
.
Individualized estimation of conditional survival for patients with spinal chordoma
Xiaoyu Ren, Fei Cong, Gao Chao, Cheng Yang, Yunshan Guo, Jinzhu Fan
Translational Cancer Research  
2025;
14
(3)
:1710-1724
.
Revisiting lymph node guidelines: limited lymph node examination might be sufficient for elderly gastric cancer patients
Xiaojie Zhang, Tao Fu, Guochao Zhang, Haibin Liu, Lin Zhang, Zongze Li, Shengnan Zhou, Lei Zhou
Translational Cancer Research  
2025;
14
(3)
:1725-1736
.
Identification of novel neutrophil-extracellular-traps-related genes as biomarkers for breast cancer prognosis and immunotherapy
Zhen Huang, Chongde Mo, Lihui Li, Qiyan Hou, Yinhua Pan, Guiyue Zhu, Fangyu Qiu, Quanqing Zou, Jianrong Yang
Translational Cancer Research  
2025;
14
(3)
:1737-1752
.
Predicting bone marrow suppression from urinal 8-hydroxy-2'-deoxyguanosine level during the treatment with radium-223 in patients with cancer bone metastasis
Satoru Monzen, Yoshihiko Kasai, Ryota Kinbara, Katsuhiko Suto, Yuki Morino, Kenji Terada, Andrzej Wojcik, Yasushi Mariya
Translational Cancer Research  
2025;
14
(3)
:1753-1763
.
Association between diffusion-weighted imaging and tumor matrix in liver cancer: a cross-sectional study
Hans-Jonas Meyer, Johann Potratz, Dörthe Jechorek, Kai Ina Schramm, Jan Borggrefe, Alexey Surov
Translational Cancer Research  
2025;
14
(3)
:1764-1771
.
Molecular subtype and prognostic model of laryngeal squamous cell carcinoma based on neutrophil extracellular trap-related genes
Guiqin Wu, Riqun Jin, Jiahua Liao, Jianhua Zhang, Xuemei Liu
Translational Cancer Research  
2025;
14
(3)
:1772-1785
.
KRT14 knockdown reduces cisplatin resistance by lowering LRP11 expression levels in cisplatin-resistant ovarian cancer cell lines
Zequn Liu, Tingsong Weng, Mi Cheng, Tingying Lei, Du Xiao, Qiong Deng, Tianmei Wu
Translational Cancer Research  
2025;
14
(3)
:1786-1798
.
Integrated machine learning constructed a circadian-rhythm-related model to assess clinical outcomes and therapeutic advantages in hepatocellular carcinoma
Ziyuan Xu, Wei Huang, Xi Zou, Shenlin Liu
Translational Cancer Research  
2025;
14
(3)
:1799-1823
.
Estrogen receptor β inhibits breast cancer migration and promotes its apoptosis through NF-κB/IL-8 signaling
Yanke Sui, Zuge Liu, Yao Yao, Shuting Zhang, Yuxiang Wang, Yuanyuan Wang, Bin Kong
Translational Cancer Research  
2025;
14
(3)
:1824-1835
.
Radiomics-clinical nomogram for preoperative tumor-node-metastasis staging prediction in breast cancer patients using dynamic enhanced magnetic resonance imaging
Zhe Yang, Shouen Wang, Wei Yin, Ying Wang, Fanghua Liu, Jianshu Xu, Long Han, Chenglong Liu
Translational Cancer Research  
2025;
14
(3)
:1836-1848
.
Causal associations between atrial fibrillation and esophageal cancer: a two-sample Mendelian randomization study
Jinsong Lei, Longjun Yang, Gongming Wang, Qianwen Liu, Guangran Guo
Translational Cancer Research  
2025;
14
(3)
:1849-1856
.
Analysis and assessment of ferroptosis-related gene signatures and prognostic risk models in skin cutaneous melanoma
Jianchao Ma, Yang Cai, Youqi Lu, Xu Fang
Translational Cancer Research  
2025;
14
(3)
:1857-1873
.
Feasibility and patient reported tolerance of cryotherapy with Cooral mouth cooling device in patients undergoing radiation therapy (CooRay): a pilot study
Andrei Bunea, Tiberiu Damian, Hatice Bunea, Tobias Finazzi, Tristan Bauer, Jens Lustenberger, Shirin Davarpanah Jazi, Alexandros Papachristofilou
Translational Cancer Research  
2025;
14
(3)
:1874-1883
.
Prediction of the prognosis of intrahepatic cholangiocarcinoma patients after hepatectomy via propensity score matching: a competitive risk model analysis
Shu-Sen Jiang, Zhi-Yu Wang, Li-Jun Tan, Li-Xia Zhou, Xue-Yao Wang, Xin-Meng Han, Shun-Gang Li, Ji-Meng Luo, Hong-Bing Yao
Translational Cancer Research  
2025;
14
(3)
:1884-1901
.
Enhanced prognostic prediction of cancer-specific mortality in elderly bladder cancer patients post-radical cystectomy: an XGBoost model study
Gaowei Li, Kang Xia
Translational Cancer Research  
2025;
14
(3)
:1902-1914
.
A novel mesenchymal epithelial transition (MET) inhibitor, CB538, relieves acquired resistance in EGFR-mutated MET-amplified non-small cell lung cancer
Ji Yeon Song, Hyunsook An, Soojeong Kim
Translational Cancer Research  
2025;
14
(3)
:1915-1927
.
Survival analysis of gastric malignancy patients: identifying key prognostic factors
Deng Han, Zhiyu Zhang, Jinyan Deng, Hongbo Du
Translational Cancer Research  
2025;
14
(3)
:1928-1941
.
Induction of ferroptosis in oxaliplatin-resistant colorectal cancer cells by extract from Actinidia chinensis Planch radix
Jun Lu, Yuhuan Wang, Wei Cui, Chenyang Ma
Translational Cancer Research  
2025;
14
(3)
:1942-1951
.
Impact of Shenling Baizhu Powder on lipid profiles and body mass index in breast cancer patients under adjuvant chemotherapy: a retrospective study
Jiaqing Song, Ying Jin, Qinghong Yu, Hongting Wu, Hailong Li, Geok Hoon Lim, Marcelo Antonini, Xiufei Gao
Translational Cancer Research  
2025;
14
(3)
:1952-1970
.
The identification and prediction of lung adenocarcinoma prognosis using a novel gene signature associated with DNA replication
Xiujuan Wu, Qiang Xu, Paerhati Aiyiti, Defeng Meng, Jingang Zhang, Fabrizio Citarella, Petros Christopoulos, Tong Liu, Wei Duan
Translational Cancer Research  
2025;
14
(3)
:1971-1981
.
Causal relationship between gut microbiota and malignant lymphoma: a two-way two-sample mendelian randomization study
Shixue Laoguo, Jing Tang, Xiaoyu Xu, Xianye Huang, Yanfeng Jiang, Ning Mo, Shanlin Duan, Weizhen Wu, Hening Li, Justin Taylor, Jie Ma
Translational Cancer Research  
2025;
14
(3)
:1982-1994
.
Biological and clinical significance of circulating mucosal-associated invariant T cells in lung cancer
Jingjing Liu, Haoyu Wang, Xiaotao Wang, Jacek Jassem, Jiming Si, Yuanhua Liu, Jianjun Jin
Translational Cancer Research  
2025;
14
(3)
:1995-2009
.
Development of coenzyme Q10-related molecular subtypes and a prognostic signature for predicting breast cancer prognosis and response to immunotherapy
Zhou Fang, Shi-Chong Liao, Yue-Yue Guo, Juan-Juan Li, Zhong Wang, Yi-Min Zhang, Feng Yao
Translational Cancer Research  
2025;
14
(3)
:2010-2028
.
Research on the error pattern recognition of dosimetric quality assurance by Bayesian optimization
Yewei Wang, Xueying Pang, Helong Wang, Yanling Bai
Translational Cancer Research  
2025;
14
(3)
:2029-2042
.
Retrospective study on the prognostic prediction of inflammatory markers and the C-reactive protein/albumin ratio in first-line immunotherapy for advanced HER2 negative gastric cancer patients
Yan Sun, Fei Yan, Xinnian Yu, Zijian Sun, Guoren Zhou
Translational Cancer Research  
2025;
14
(3)
:2043-2053
.
A gene signature associated with cellular senescence serves as an important prognostic indicator in hepatocellular carcinoma
Yongfeng Yan, Kai Chen, Qian Sun
Translational Cancer Research  
2025;
14
(3)
:2054-2065
.
Diagnostic test of conventional ultrasonography combined with contrast-enhanced ultrasound in the subcategorization of suspicious Breast Imaging-Reporting and Data System (BI-RADS) 4 breast lesions
Yindi Zhu, Dian Zhang, Xiao-Na Wang, Yue-Nan Chen, Mei-Fang Pan, Susanna Guerrini, Eugene Ong, Xin-Xian Gu, Li Jiang
Translational Cancer Research  
2025;
14
(3)
:2066-2077
.
Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway
Xingxing Gao, Genyun Liu, Zimu Zhao, Yi Tang, Hui Hui, Chaoqun Wang, Danhua Li, Yu Ma, Zhuo Sun, Yun Zhou
Translational Cancer Research  
2025;
14
(3)
:2078-2094
.
Investigation of mitochondrial DNA methylation-related prognostic biomarkers in hepatocellular carcinoma using The Cancer Genome Atlas (TCGA) database
Shanfan Shi, Wen Liang, Yunxue Qie, Runtong Wu, Yejin Zhu
Translational Cancer Research  
2025;
14
(3)
:2095-2112
.
Construction of a postoperative liver metastasis prediction model for colorectal cancer based on spectral CT imaging, CEA, and CA19-9
Qingyong Yang, Chenguang Bai, Yongzi Xu, Yan Sun, Diamantis I. Tsilimigras, Yousheng Lu
Translational Cancer Research  
2025;
14
(3)
:2113-2124
.

Letter to the Editor

Central nervous system and osteodural multiple myeloma
Alessandro Gozzetti
Translational Cancer Research  
2025;
14
(3)
:2168-2169
.