Vol 10, No 5 (May 27, 2021): Translational Cancer Research

Original Article

Characteristics of esophageal cancer in patients with head and neck squamous cell carcinoma
Lei Wang, Wenjing Pang, Kun Zhou, Lei Li, Feng Wang, Wei Cao, Xiangjun Meng
Translational Cancer Research  
2021;
10
(5)
:1954-1961
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 (27 May 2021) 
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Construction of a prognostic risk model of colorectal adenocarcinoma through integrated analysis of RNA-binding proteins
Xinhong Liu, Qikun Lv, Zuolin Jing, Xingyao Long, Ruokun Yi, Dingyi Yang, Xin Zhao
Translational Cancer Research  
2021;
10
(5)
:1962-1974
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 (27 May 2021) 
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Bruton’s tyrosine kinase inhibitors in primary central nervous system lymphoma—evaluation of anti-tumor efficacy and brain distribution
Haifeng Yu, Haiying Kong, Cong Li, Xiaowu Dong, Yizhe Wu, Yuxin Zhuang, Shuiyun Han, Tao Lei, Haiyan Yang
Translational Cancer Research  
2021;
10
(5)
:1975-1983
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 (27 May 2021) 
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Postmastectomy radiation therapy can improve survival for breast cancer patients with 1–3 positive axillary lymph nodes: a retrospective cohort study using the SEER database
Jian Yang, Xiao Zhang, Yifeng Ye, Yunyan Lin, Qingmo Yang, Haoyang Cai
Translational Cancer Research  
2021;
10
(5)
:1984-2001
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 (27 May 2021) 
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Clinical characteristics and prediction model of long time survival of patients with stage M1 Siewert type II esophagogastric junction adenocarcinoma
Jun Zhang, Deruo Liu
Translational Cancer Research  
2021;
10
(5)
:2002-2008
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 (27 May 2021) 
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Identification of prognostically relevant gene signatures in lung squamous cell carcinoma by Lung Cancer Explorer
Yuqing Wang, Juan Shen, Jie Huang
Translational Cancer Research  
2021;
10
(5)
:2009-2022
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 (27 May 2021) 
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Procyanidins mediates antineoplastic effects against non-small cell lung cancer via the JAK2/STAT3 pathway
Yue Wu, Chi Liu, Yuxu Niu, Jiamin Xia, Liwen Fan, Yun Wu, Wen Gao
Translational Cancer Research  
2021;
10
(5)
:2023-2035
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 (27 May 2021) 
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Expression patterns and clinical significances of PBK in lung cancer: an analysis based on Oncomine database
Jinglei Li, Wei Hou
Translational Cancer Research  
2021;
10
(5)
:2036-2043
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 (27 May 2021) 
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RCHOP-14 therapy versus RCHOP-21 therapy for people with aggressive or advanced-stage indolent B-cell non-Hodgkins lymphoma: a systematic review and meta-analysis
Yue He, Wenqiang Tao, Dexiang Ji, Wei Lu, Yu Xiong, Guoan Chen
Translational Cancer Research  
2021;
10
(5)
:2044-2054
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 (27 May 2021) 
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Aspirin induced long non coding RNA suppresses colon cancer growth
Mingwei Chen, Lili Wu, Huajie Zhan, Tonghua Liu, Yan He
Translational Cancer Research  
2021;
10
(5)
:2055-2069
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 (27 May 2021) 
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Association between insulin-like growth factor 1 gene rs5742612 polymorphism and malignant tumor susceptibility: a meta-analysis
Xueliang Zhou, Jinpeng Zhang, Yan Zheng, Tao Wei
Translational Cancer Research  
2021;
10
(5)
:2070-2079
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 (27 May 2021) 
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Effectiveness and safety of focused ultrasound ablation surgery compared with radiofrequency ablation in primary hepatocellular carcinoma treatment: a meta-analysis
Jian-Ying Zhang, Long Chen, Rong Ma, Chun-Mu Miao, Yun-Bing Wang
Translational Cancer Research  
2021;
10
(5)
:2080-2090
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 (27 May 2021) 
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Effectiveness and safety of combined therapy versus monotherapy based on immune checkpoint inhibitors and/or targeted drugs as salvage treatment for advanced urothelial carcinoma: a systematic review and meta-analysis
Lichao Wei, Liang Gao, Zili Hu, Chuan Liu
Translational Cancer Research  
2021;
10
(5)
:2091-2107
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 (27 May 2021) 
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The predictive and prognostic value of sex in localized colorectal cancer: a SEER-based analysis
Bin Ma, Yongmin Li, Qingkai Meng
Translational Cancer Research  
2021;
10
(5)
:2108-2119
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 (27 May 2021) 
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The compound AST-003 could effectively promote apoptosis of renal cell carcinoma cells in vitro
Xingxing Tang, Qiang Zhao, Jia Liu, Shuo Wang, Ning Zhang, Yong Yang
Translational Cancer Research  
2021;
10
(5)
:2120-2133
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 (27 May 2021) 
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Genetic variations of rs6928 and rs5999521 of ERK2 were found to have correlation with the risk of brain metastasis in patients with lung adenocarcinoma
Bo Li, Zheng Lv, Gang Zhao, Youqi Li, Xiaoguang Qiu
Translational Cancer Research  
2021;
10
(5)
:2134-2143
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 (27 May 2021) 
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Survival outcomes for patients with four treatments in stages I–III esophageal squamous cell carcinoma: a SEER analysis
Jingyang Wu, Jiansheng Yang, Xianbin Lin, Liang’an Lin, Wentan Jiang, Chengke Xie
Translational Cancer Research  
2021;
10
(5)
:2144-2152
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 (27 May 2021) 
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PUM1 is upregulated by DNA methylation to suppress antitumor immunity and results in poor prognosis in pancreatic cancer
Yishi Yang, Xingxing Su, Kaicheng Shen, Chengcheng Zhang, Haisu Dai, Hongbo Ma, Yan Jiang, Ling Shuai, Zhipeng Liu, Jinshan You, Ke Min, Zhiyu Chen
Translational Cancer Research  
2021;
10
(5)
:2153-2168
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 (27 May 2021) 
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Functions of CXC chemokines as biomarkers and potential therapeutic targets in the hepatocellular carcinoma microenvironment
Jukun Wang, Chao Zhang, Xin Chen, Yu Li, Ang Li, Dongbin Liu, Fei Li, Tao Luo
Translational Cancer Research  
2021;
10
(5)
:2169-2187
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 (27 May 2021) 
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Is metabolic syndrome associated with high tumor grade and stage of bladder cancer: a systematic review and meta-analysis
Dechao Feng, Pan Song, Yubo Yang, Wuran Wei, Li Li
Translational Cancer Research  
2021;
10
(5)
:2188-2198
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 (27 May 2021) 
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Clinical features and prognostic factors of male breast cancer vs. female breast cancer
Guo Sang, Hong Pan, Chen Lu, Rongneng Sun, Xiaoming Zha, Shui Wang, Dongya Zhu
Translational Cancer Research  
2021;
10
(5)
:2199-2209
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 (27 May 2021) 
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PD-L1 expression and patient outcomes in gastrointestinal neuroendocrine neoplasm: a meta-analysis
Woojoo Lee, Min-ju Kim, Younghee Choi, Hyunchul Kim
Translational Cancer Research  
2021;
10
(5)
:2210-2218
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 (27 May 2021) 
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Targeting COX-2 potently inhibits proliferation of cancer cells in vivo but not in vitro in cutaneous squamous cell carcinoma
Lipeng Gao, Tim Hua Wang, Champ Peng Chen, Jan Jian Xiang, Xu-Bo Zhao, Rong-Yin Gui, Xin-Hua Liao
Translational Cancer Research  
2021;
10
(5)
:2219-2228
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 (27 May 2021) 
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A six-gene signature related with tumor mutation burden for predicting lymph node metastasis in breast cancer
Cenzhu Wang, Kun Xu, Fei Deng, Yiqiu Liu, Jinyi Huang, Runtian Wang, Xiaoxiang Guan
Translational Cancer Research  
2021;
10
(5)
:2229-2246
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 (27 May 2021) 
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Analysis of the clinical value of multi-slice spiral computed tomography (MSCT), magnetic resonance imaging (MRI) and ultrasound (US) in the diagnosis of retroperitoneal tumors
Yuanchun Feng, Wei Zhang, Chenghua Luo
Translational Cancer Research  
2021;
10
(5)
:2247-2254
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 (27 May 2021) 
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Serum amyloid A protein in cancer prognosis: a meta-analysis and systematic review
Yucheng Lai, Yuting Li, Leilei Gao
Translational Cancer Research  
2021;
10
(5)
:2255-2264
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 (27 May 2021) 
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Diagnostic value of circulating cell-free DNA for renal cell carcinoma: a meta-analysis
Yong Li, Peng Chen, Zhi Chen
Translational Cancer Research  
2021;
10
(5)
:2265-2276
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 (27 May 2021) 
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Inactivation of Wnt-LRP5 signaling suppresses the proliferation and migration of ovarian cancer cells
Jing Hong, Zeyu Xie, Zhihua Yang, Fangyao Yang, Hai Liao, Shuquan Rao, Xinhe Huang
Translational Cancer Research  
2021;
10
(5)
:2277-2285
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 (27 May 2021) 
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Bioinformatic analysis of the expression and prognosis of ZNF589 in human breast cancer
Jun Fan, Zhe Zhang, Dongjiao Chen, Hongqiang Chen, Wenbo Yuan, Lu Zhou, Jing Xu, Wenbin Liu, Yan Xu
Translational Cancer Research  
2021;
10
(5)
:2286-2304
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 (27 May 2021) 
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PD-L1 combined with HDAC9 is a useful prognostic predictor in hepatocellular carcinoma
Zhao Yang, Lei Zhang, Jianwei Liu, Lixue Yang, Hui Xue, Shilei Bai, Kui Wang
Translational Cancer Research  
2021;
10
(5)
:2305-2317
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 (27 May 2021) 
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Decreased expression of nuclear factor 90 correlates with worse outcomes in nasopharyngeal carcinoma
Yong Li, Jianchang Fu, Zi-Zi Li, Qiufang Zhu, Keming Chen, Huixiong Du, Jun Liu, Yingqing Li
Translational Cancer Research  
2021;
10
(5)
:2318-2327
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 (27 May 2021) 
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Mid-to-long term oncologic and functional outcomes of zero ischemia laparoscopic microwave ablation-assisted tumor enucleation for renal cell carcinoma: a single-center experience
Jiale Zhou, Xiaorong Wu, Jin Zhang, Jiwei Huang, Yonghui Chen
Translational Cancer Research  
2021;
10
(5)
:2328-2336
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 (27 May 2021) 
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Construction of five microRNAs prognostic markers and a prognostic model for clear cell renal cell carcinoma
Qi Zhou, Zhi-Yu Zhang, Xiao-Jie Ang, Can Hu, Jun Ouyang
Translational Cancer Research  
2021;
10
(5)
:2337-2353
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 (27 May 2021) 
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A novel immune-related gene signature predicts survival in esophageal squamous cell carcinoma
Tao Xu, Tianyang Dai, Peiyuan Zeng, Yunfen Guo, Kaiming He
Translational Cancer Research  
2021;
10
(5)
:2354-2367
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 (27 May 2021) 
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The E3 protein ubiquitin ligase Itch is a potential target in myeloid malignancies with marrow fibrosis
Shuang Han, Yao Zhang, Cha Guo, Chunkang Chang
Translational Cancer Research  
2021;
10
(5)
:2368-2378
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 (27 May 2021) 
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Long noncoding RNA DATOC-1 that associate with DICER promotes development in epithelial ovarian cancer by upregulating miR-7 expression
Wenxing Qin, Yuqing Miao, Guangxia Sun, Shiqi Chen, Yuan-Sheng Zang, Chao Dong
Translational Cancer Research  
2021;
10
(5)
:2379-2388
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 (27 May 2021) 
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The expression of myosin-regulated light chain interacting protein (MYLIP) in lung cancer and its inhibitory effects on lung carcinomas
Wenhui Wang, Fenqiang Li, Peiying Gan, Dongjun Su, Gengxiang Li, Lei Dang, Yuxing Peng
Translational Cancer Research  
2021;
10
(5)
:2389-2398
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 (27 May 2021) 
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Bioinformatics analysis on enrichment analysis of potential hub genes in breast cancer
Limin Wei, Yukun Wang, Dan Zhou, Xinyang Li, Ziming Wang, Ge Yao, Xinshuai Wang
Translational Cancer Research  
2021;
10
(5)
:2399-2408
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 (27 May 2021) 
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Clinical value of traditional laparotomy, extensive vaginal hysterectomy, and laparoscope-assisted vaginal hysterectomy in the treatment of patients with cervical intraepithelial neoplasia III
Yao Xu, Haiyan Wu, Chaolin Huang, Ling Lu
Translational Cancer Research  
2021;
10
(5)
:2409-2415
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 (27 May 2021) 
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Up-regulation of SOCS4 promotes cell proliferation and migration in esophageal squamous cell carcinoma
Jie Ying, Huan-Huan Huang, Miao-Miao Zhang, Jin-Fei Chen
Translational Cancer Research  
2021;
10
(5)
:2416-2427
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 (27 May 2021) 
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A systematic review and meta-analysis of the influence of STAS on the long-term prognosis of stage I lung adenocarcinoma
Yanhui Yang, Xiaoyang Xie, Yi Wang, Xiaoliang Li, Lei Luo, Yi Yao, Ji Li
Translational Cancer Research  
2021;
10
(5)
:2428-2436
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 (27 May 2021) 
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Curcumol increases the sensitivity of colon cancer to 5-FU by regulating Wnt/β-catenin signaling
Jinfeng Gao, Daorong Hou, Ping Hu, Guoxin Mao
Translational Cancer Research  
2021;
10
(5)
:2437-2450
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 (27 May 2021) 
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Abnormal arginine metabolism is associated with prognosis in patients of gastric cancer
Lin-Yang Shi, Yuan-Yuan Wang, Yu Jing, Ming-Hao Xu, Zhi-Tu Zhu, Qing-Jun Wang
Translational Cancer Research  
2021;
10
(5)
:2451-2469
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 (27 May 2021) 
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The expression of Nanog protein and fibroblast growth factor-inducible molecule 14 in patients with non-small cell lung cancer and their relationship with pathological characteristics and prognosis
Yaqian Wang, Ping Zhou, Cunxiao Cui, Xinxia He, Yali Bian, Xiuzheng Wang
Translational Cancer Research  
2021;
10
(5)
:2470-2477
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 (27 May 2021) 
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Review Article

The application of artificial intelligence in lung cancer: a narrative review
Huixian Zhang, Die Meng, Siqi Cai, Haoyue Guo, Peixin Chen, Zixuan Zheng, Jun Zhu, Wencheng Zhao, Hao Wang, Sha Zhao, Jia Yu, Yayi He
Translational Cancer Research  
2021;
10
(5)
:2478-2487
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 (27 May 2021) 
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A narrative review of Safety management of 1 L platinum-based chemotherapy and maintenance olaparib in BRCA mutated advanced pancreatic cancer
Jiayu Yao, Yongchao Wang, Tiebo Mao, Yiyi Liang, Xiao Zhang, Haiyan Yang, Jiong Hu, Feng Jiao, Jiujie Cui, Liwei Wang
Translational Cancer Research  
2021;
10
(5)
:2488-2495
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 (27 May 2021) 
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Case Report

Adenosquamous carcinoma of the hepatic flexure of colon: a case report: a case report
Bo Huang, Hongmei Li, Ping Li
Translational Cancer Research  
2021;
10
(5)
:2496-2502
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 (27 May 2021) 
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Primary neuroendocrine carcinoma of the breast with markedly elevated alpha-fetoprotein: a case report
Jia Wang, Xichen Wang, Wenlong Du, Yuanxian Guo, Xiaoping Yang, Jiebin Pan, Lanning Yin
Translational Cancer Research  
2021;
10
(5)
:2503-2508
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 (27 May 2021) 
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Imaging of synchronous multiple primary lung adenocarcinoma with concomitant EGFR and KRAS mutations: a case report and review of the literature
Jing-Wen Ma, Yong-Liang Fu, Lei Miao, Meng Li
Translational Cancer Research  
2021;
10
(5)
:2509-2515
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 (27 May 2021) 
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Study Protocol

Effect of electroacupuncture on chemotherapy-induced diarrhea: study protocol for a randomized controlled trial
Yuhang Wang, Mingfei Zhou, Jianmei Shen, Dongsheng Wang, Na Xu, Yafang Song, Mengzhu Sun, Lu Chen, Lixia Pei, Jianhua Sun
Translational Cancer Research  
2021;
10
(5)
:2516-2524
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 (27 May 2021) 
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Editorial on Synergy in Action: Novel Approaches to Combining Radiation Therapy and Immunotherapy1

Radiation and immunotherapy: united as one in the fight against cancer
Arya Amini, Tyler Robin
Translational Cancer Research  
2021;
10
(5)
:2525-2526
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 (27 May 2021) 
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Review Article on Synergy in Action: Novel Approaches to Combining Radiation Therapy and Immunotherapy1

Narrative review of immune checkpoint inhibitors and radiation therapy for brain metastases
Marina Moskalenko, Tyler P. Robin
Translational Cancer Research  
2021;
10
(5)
:2527-2536
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 (27 May 2021) 
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Immunotherapy and radiation for high-grade glioma: a narrative review
Kareem R. Fakhoury, Douglas E. Ney, D. Ryan Ormond, Chad G. Rusthoven
Translational Cancer Research  
2021;
10
(5)
:2537-2570
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 (27 May 2021) 
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Combinations of immunotherapy and radiation therapy in head and neck squamous cell carcinoma: a narrative review
Thomas J. Hayman, Aarti K. Bhatia, Krishan R. Jethwa, Melissa R. Young, Henry S. Park
Translational Cancer Research  
2021;
10
(5)
:2571-2585
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 (27 May 2021) 
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A narrative review of combining radiation and immunotherapy in gastroesophageal cancers
Kevin Yoon, Yi-Jen Chen, Joseph Chao
Translational Cancer Research  
2021;
10
(5)
:2586-2595
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 (27 May 2021) 
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The utilization of immunotherapy with radiation therapy in lung cancer: a narrative review
John H. Heinzerling, Kathryn F. Mileham, Charles B. Simone II
Translational Cancer Research  
2021;
10
(5)
:2596-2608
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 (27 May 2021) 
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Combination radiation and immunotherapy in gynecologic malignancies—a comprehensive review
Colton Ladbury, Elizabeth Germino, Jennifer Novak, Jason Liu, Zachary Horne, Brandon Dyer, Scott Glaser
Translational Cancer Research  
2021;
10
(5)
:2609-2619
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 (27 May 2021) 
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Narrative review of immunotherapy and radiation therapy in elderly patients
Brittney Chau, Jonnby LaGuardia, Caressa Hui, Linda Ye, Yan Xing, Erminia Massarelli, Arya Amini
Translational Cancer Research  
2021;
10
(5)
:2620-2631
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 (27 May 2021) 
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Disclosure:

1. The series “Synergy in Action: Novel Approaches to Combining Radiation Therapy and Immunotherapy” was commissioned by the editorial office, Translational Cancer Research without any sponsorship or funding. Arya Amini and Tyler Robin served as the unpaid Guest Editors for the series.