Vol 14, No 1 (January 31, 2025): Translational Cancer Research

Editorial Commentary

The heterogeneity in oligoprogression and stereotactic body radiation therapy
Takafumi Hayashi, Nagio Takigawa
Translational Cancer Research  
2025;
14
(1)
:1-6
.
Small cell lung carcinoma with YAP1 expression and SMARCA4-deficient undifferentiated tumors
Takuo Hayashi
Translational Cancer Research  
2025;
14
(1)
:7-10
.
Navigating restriction from interstitial lung disease (ILD) with stereotactic ablative radiotherapy (SABR) in early-stage non-small cell lung cancer: soaring beyond the current treatment paradigm
Ari A. Kassardjian, Jyoti Malhotra, Percy Lee
Translational Cancer Research  
2025;
14
(1)
:11-15
.
How to select between osimertinib or afatinib in P-loop and αC-helix compressing (G719X, S768I) or classical-like (L861Q) EGFR mutations: what preclinical models and clinical data have taught us in the early 2020s
Julia M. Berg, Toshiki A. Kobayashi, Daniel B. Costa
Translational Cancer Research  
2025;
14
(1)
:16-23
.
On the precipice of a new generation of biomarkers for immunotherapy in small cell lung cancer
Peiran Sun, Stephanie Snow
Translational Cancer Research  
2025;
14
(1)
:24-28
.
Optimizing immunotherapy for lung cancer: integrating genetic alterations and the tumor mutational burden to refine patient selection
Takahiro Sugawara, Taiki Hakozaki, Masahiro Seike, Yukio Hosomi
Translational Cancer Research  
2025;
14
(1)
:29-32
.

Original Article

Prognostic development and validation of a prediction model based on major histocompatibility complex-related differentially expressed genes in stomach adenocarcinoma
Tianqi Wang, Yiran Liu, Shengjie Ma, Binxu Qiu, Quan Wang
Translational Cancer Research  
2025;
14
(1)
:33-61
.
Assessing mortality risk and causes in extramammary Paget’s disease: insights from a population-based study
Xiaohui Qiu, Dong-Dong Yu, Hui Dong, Xiang Liu
Translational Cancer Research  
2025;
14
(1)
:62-70
.
Testosterone and colorectal cancer: a bidirectional Mendelian randomization study
Junxing Li, Xinmei Yan, Huyu Jiao, Jingjing Chen, Zhengang Zhang
Translational Cancer Research  
2025;
14
(1)
:71-77
.
METTL3 stabilizes SERPINE2 via the m6A modification to drive the malignant progression of gastric signet ring cell carcinoma
Tan Yan, Qian Wang, Yuhui Liu
Translational Cancer Research  
2025;
14
(1)
:78-92
.
A new risk algorithm combining D-dimer and HE4 differentiates borderline tumor from patients with ovarian tumor
Mi Zhang, Ya Zhang, Guangquan Liu, Lili Ge
Translational Cancer Research  
2025;
14
(1)
:93-101
.
Analysis of the quality of vulvar cancer-related videos on YouTube
Ting Xu, Hui Zhao
Translational Cancer Research  
2025;
14
(1)
:102-111
.
Mitochondrial single-stranded DNA binding protein 1 (SSBP1) high expression as a potential biomarker and association with poor prognosis in hepatocellular carcinoma (HCC)
Ya-Ru Lin, Jian-Kang Li, Xi Yang, Bao-Ru Dong, Ru-Ai Liu, Xin-Meng Wang, Min Yu, Wei Xiong
Translational Cancer Research  
2025;
14
(1)
:112-128
.
Cuproptosis-related genes signature could predict prognosis and the response of immunotherapy in cervical cancer
Xue Liu, Wei Li, Chun Yang, Judong Luo, Bin Tang
Translational Cancer Research  
2025;
14
(1)
:129-140
.
Development of a nomogram predicting perineural invasion risk and assessment of the prognostic value of perineural invasion in colon cancer: a population study based on the Surveillance, Epidemiology, and End Results database
Zhongqiang Zheng, Xuanzi Sun
Translational Cancer Research  
2025;
14
(1)
:141-158
.
Development and validation of a prognostic model based on disulfidptosis-related ferroptosis genes: DRD4 and SLC2A3 as biomarkers for predicting prognosis in colon cancer
Nan Yi, Yuanzi Zhou, Dong Di, Xindong Yin, Xiao Feng, Wenya Xing, Chaoqun Ma, Cunbing Xia
Translational Cancer Research  
2025;
14
(1)
:159-178
.
A 5-lncRNA signature predicts clinical prognosis and demonstrates a different mRNA expression in adult soft tissue sarcoma
Ye Yao, Xiaojuan Wang, Ziwei Zhao, Zhipeng Li
Translational Cancer Research  
2025;
14
(1)
:179-196
.
By integrating single-cell RNA sequencing and bulk RNA sequencing, plasma cells signature and tertiary lymphoid structures were verified to contribute to outcome in lung adenocarcinoma
Zetian Gong, Xianchuang Xu, Yaolin Cao, Yanlong Feng, Jiatao Liu, Jinpeng Yang, Wenyu Wang, Hui Gong, Jun Li, Liang Chen, Wei Wang
Translational Cancer Research  
2025;
14
(1)
:197-211
.
Single nucleotide polymorphism and promoter methylation analysis of protein tyrosine phosphatase 1B in patients with myeloproliferative neoplasms
Jie Zhou, Hao Wu, Bing Li, Lili Zhou, Wenjun Zhang, Yi Ding, Xinyu Zhu, Huina Lu, Bing Xiu, Aibin Liang, Jianfei Fu
Translational Cancer Research  
2025;
14
(1)
:212-224
.
Establishment and validation of predictive models by mutational and transcriptional factors for the prognosis of stage IV colorectal cancer patients with liver metastasis who undergo palliative surgery on primary tumors
Sijia Shen, Xu Zhang
Translational Cancer Research  
2025;
14
(1)
:225-239
.
Establishment and validation of a prognostic prediction model for glioma based on key genes and clinical factors
Yu Lin, Huining Li, Qiang Ge, Dan Hua
Translational Cancer Research  
2025;
14
(1)
:240-253
.
Construction and validation of a prognostic signature using WGCNA-identified key genes in osteosarcoma for treatment evaluation
Zhuo Chen, Renhua Ni, Yuanyu Hu, Yiyuan Yang, Jiawen Chen, Yun Tian
Translational Cancer Research  
2025;
14
(1)
:254-271
.
Association of systemic inflammatory response index with all-cause and malignant neoplasm mortality in patients with gastrointestinal disease
Peng Wang, Hongwei Zhu, Shuyuan Jiang, Xiaolei Liu, Bing Gao, Wanfu Bai, Wei Xie, Guo Shao
Translational Cancer Research  
2025;
14
(1)
:272-285
.
Emodin reverses sorafenib resistance in hepatocellular carcinoma by inhibiting epithelial-mesenchymal transition via the Akt signaling pathway
Qingqing Wang, Jie Zhang
Translational Cancer Research  
2025;
14
(1)
:286-295
.
Diagnostic value of a lactylation-related gene signature in hepatocellular carcinoma
Jiajia Zhang, Chunmei Dong, Lili Wu, Lei Chen, Lijiang Zhang, Liang Shi
Translational Cancer Research  
2025;
14
(1)
:296-312
.
Association between surrogate indices of fatty liver and the risk of colorectal cancer: a cross-sectional United States study
Chenyuan Shi, Chao Yuan, Yifei Hao, Zheng Zhou, Yigang Zhang
Translational Cancer Research  
2025;
14
(1)
:313-326
.
Immune checkpoint inhibitors plus paclitaxel-based chemotherapy vs. oxaliplatin-based therapy as first-line treatment for patients with HER2-negative unresectable or metastatic gastric/gastroesophageal junction cancer: results of a multicenter retrospective study
Yulu Fang, Yifan Zhao, Xiaoling Zhang, Xiaofu Yu, Shuxun Liu, Gang Tao, Yunshan Yang, Haijun Zhong, Zhong Shi
Translational Cancer Research  
2025;
14
(1)
:327-339
.
Deciphering the prognostic potential of a necroptosis-related gene signature in head and neck squamous cell carcinoma: a bioinformatic analysis
Shizhe Wang, Junjian Jiang, Min Xing, Hongru Su
Translational Cancer Research  
2025;
14
(1)
:340-353
.
EPB41L4A-AS1 regulates cervical cancer by proliferative cells: mendelian randomization and single-cell transcriptomics analyses
Yifan Wang, Jia Yao, Meilian Wei, Qianru Jiang, Haiming Luo, Sidan Lai, Zhulin Liu, Hongsheng Zou, Chenlong Wang, Meijian Liao
Translational Cancer Research  
2025;
14
(1)
:354-370
.
Impact of systemic immune-inflammation index and its evaluation of optimal threshold in patients with limited-stage small cell lung cancer: a retrospective study based on 572 cases
Ziling Zhang, Yan Zhao, Junpeng Wen, Yuxiang Wang, Juan Li
Translational Cancer Research  
2025;
14
(1)
:371-382
.
Comparative efficacy of transarterial chemoembolization with and without PD-1 inhibitor in the treatment of unresectable liver cancer and construction and validation of prognostic models
Ming-Xing Wang, Tong Lai, Ai-Xin Liu, Gong-Yi Wu, Qing-Ming Sun, Bao-Rui Zhang, Wan-Hui Dong
Translational Cancer Research  
2025;
14
(1)
:383-403
.
Establishing a prognostic scoring system and exploring prognostic value of examined lymph node numbers for stage I non-small cell lung cancer: a retrospective study of Surveillance, Epidemiology, and End Results (SEER) database and a Chinese cohort
Siyuan Wang, Xin Yin, Lingyun Wu, Hao Yu, Zhongjie Lu, Feng Zhao, Danfang Yan, Senxiang Yan
Translational Cancer Research  
2025;
14
(1)
:404-423
.
Level and clinical significance of serum CXC chemokine ligand 13 in patients with hepatocellular carcinoma
Ye-Ting Wu, Xiao-Juan Ran, Qi-Zhe Li, Yi-Qi Wu, Xiao-Xu Shen, Mao Mu, Quan Zhang
Translational Cancer Research  
2025;
14
(1)
:424-433
.
Single-cell programmed cell death regulator patterns guide intercellular communication of cancer-associated fibroblasts that contribute to colorectal cancer progression
Kai Yao, Shuo Zhang, Bo Zhu, Yun Sun, Ke Tian, Yan Yan, Yongquan Hu, Li Ren, Congli Zhang
Translational Cancer Research  
2025;
14
(1)
:434-460
.
Relationship between survival outcomes in patients with colorectal liver metastasis undergoing hepatectomy and significance of fibrotic markers for liver injury assessment
Atsushi Nanashima, Masahide Hiyoshi, Naoya Imamura, Takeomi Hamada, Yuki Tsuchimochi, Ikko Shimizu, Takahiro Ochiai, Akiko Ichihara, Kiyoaki Hamada, Nobuhiko Ichiki, Kengo Kai, Kazuhiro Higuchi
Translational Cancer Research  
2025;
14
(1)
:461-472
.
Association between serum urate levels, gout and breast cancer: observational and Mendelian randomization analyses
Shuai Wang, Zhiyuan Zhang, Yuqing Su, Shoukai Wang, Wenwen Li, Qi Liu, Pilei Si, Wentao Li
Translational Cancer Research  
2025;
14
(1)
:473-485
.
Potential therapeutic targets for colorectal cancer and its subsites: evidence from the proteome-wide Mendelian randomization analyses
Jinyi Li, Yuanda Liu, Chang Liu, Pengtuo Xiao
Translational Cancer Research  
2025;
14
(1)
:486-496
.
Oxidative phosphorylation-related genes for prognosis and tumor microenvironment in breast cancer
Man-Zhi Xia, Shu-Feng Dong, Chun-Lei Wang
Translational Cancer Research  
2025;
14
(1)
:497-511
.
Unlocking the future: mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response
Zhijian Tang, Yuanming Pan, Wei Li, Ruiqiong Ma, Jianliu Wang
Translational Cancer Research  
2025;
14
(1)
:512-521
.
ARNTL2: a key player in promoting tumor aggressiveness in papillary thyroid cancer
Qing Zhai, Han Wu, Shiqiang Liu, Yuehong Zhu, Xi Huang, Junfeng Wang
Translational Cancer Research  
2025;
14
(1)
:522-534
.
Adenanthin inhibits pancreatic cancer proliferation by regulation of H2O2/ROS
Yao Fei, Anqi Wang, Yifan Zhao
Translational Cancer Research  
2025;
14
(1)
:535-544
.
A predictive nomogram for predicting liver metastasis in early-onset colon cancer: a population-based study
Weichao Zeng, Yafeng Sun, Zhengrong Liao, Jianhua Xu
Translational Cancer Research  
2025;
14
(1)
:545-553
.
Based on network pharmacology and experimental validation, berberine can inhibit the progression of gastric cancer by modulating oxidative stress
Xiaodong Han, Qiuzan Zhang, Dandan Cao, Yanrong Wang, Sipu Wang, Qijin He, Jingwen Zhao, Xin Chen
Translational Cancer Research  
2025;
14
(1)
:554-568
.
Analysis and exploration of regulatory mechanisms and potential prognostic biomarkers in squamous cell carcinoma of the lung by expression profiling
Xiaoxi Wan, Chuanxia Zhang, Mengyuan Kang, Antonio Rossi, Taichiro Goto, Nagarashee Seetharamu, Nobuhiko Seki, Heng Lu, Yang Zhang
Translational Cancer Research  
2025;
14
(1)
:569-583
.
LncRNA ZEB1-AS1 promotes the proliferation and migration of non-small cell lung cancer by activating epithelial-mesenchymal transition with STAT3
Zhengjin Chen, Yangwei Yao, Jingpeng Gao
Translational Cancer Research  
2025;
14
(1)
:584-594
.
FTO-mediated m6A demethylation of SERPINE1 mRNA promotes tumor progression in hypopharyngeal squamous cell carcinoma
Na Sa, Xuliang Liu, Dake Hao, Zhenghua Lv, Shengli Zhou, Linxue Yang, Shan Jiang, Jiajun Tian, Wei Xu
Translational Cancer Research  
2025;
14
(1)
:595-612
.
Identification and validation of LINC02381 as a biomarker associated with lymph node metastasis in esophageal squamous cell carcinoma
Jin Liang, Zhengang Zhao, Yujie Xie, Dongmei Lai, Ikenna C. Okereke, Jeffrey B. Velotta, Emmanuel Gabriel, Wanli Lin
Translational Cancer Research  
2025;
14
(1)
:613-625
.
Exploration of key pathogenic mechanisms and potential intervention targets of the traditional Chinese medicine Coptis chinensis in the treatment of cervical cancer based on network pharmacology and molecular docking techniques
Ying Hou, Lei Zhang, Hequn Li, Renmin Zhang, Jiaxing Sun, Hui Jia, Hui Xu
Translational Cancer Research  
2025;
14
(1)
:626-639
.
A diagnostic test of two-dimensional ultrasonic feature extraction based on artificial intelligence combined with blood flow Adler classification and contrast-enhanced ultrasound for predicting HER-2-positive breast cancer
Kun Wang, Xi Yang, Shuo Yang, Xian Du, Ruijing Shi, Wendong Bai, Yu Wang
Translational Cancer Research  
2025;
14
(1)
:640-650
.

Surgical Technique

Nerve sparing excision of gastrohepatic ligament lesion as part of cytoreductive surgical management of advanced ovarian malignancy
Sarah Louise Smyth, Aakriti Aggarwal, Hooman Soleymani majd
Translational Cancer Research  
2025;
14
(1)
:651-655
.

Erratum

Erratum: miR-137 represses migration and cell motility by targeting COX-2 in non-small cell lung cancer
Editorial Office
Translational Cancer Research  
2025;
14
(1)
:656-657
.

Retraction

Retraction: MicroRNA-153-3p sensitizes melanoma cells to dacarbazine by suppressing ATG5-mediated autophagy and apoptosis
Shaowei Hou, Minfang Guo, Haiying Xi, Lianqing Zhang, Ailing Zhao, Heng Hou, Wuning Fang
Translational Cancer Research  
2025;
14
(1)
:658-659
.