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Join us at the 33rd Annual Meeting of the European Society of Thoracic Surgery (ESTS)

The 33rd Annual Meeting of the European Society of Thoracic Surgery is going to be held in May 25-27, 2025 in Budapest, Hungary: https://estsmeeting.com.

This time, Translational Cancer Research (TCR) as well as its sister journals and books published by AME Publishing Company will be on display during this exciting academic event! We would like to seize this great opportunity to meet our authors, editorial board members and readers.

Reviewer of the Month (2025)

In 2025, TCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Interviews with Outstanding Authors (2025)

In 2025, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspectives and insightful views as authors.

TCR 2024 Annual Report

Greetings from the Editorial Office of TCR!

We are pleased to share the 2024 Annual Report of Translational Cancer Research. 2024 has seen much progress for TCR. We hope 2025 will bring greater things to TCR. We would like to thank you for your support and assistance in improving the journal over the past year, and we certainly look forward to your innovations and contributions in 2025.

We would especially like to express our sincere gratitude to the editorial board members, guest editors, reviewers, authors, and readers for all your support and contributions to TCR. We wish you a happy, healthy and prosperous 2025!

Interviews with Editorial Board Members

TCR features a distinguished editorial board, the members of which continue to instill the power of their expertise for the journal’s development. By launching this column, we are glad to introduce to you some of them in the form of interviews, in which they will share their unique career experiences and perspectives. We believe their insights will shed light on the knowledge of related fields.

Interviews with Guest Editors

Over the years, a number of TCR guest editors have made valuable contributions to the journal. This column features interviews with our guest editors, who graciously share their experience in scientific careers and provide insightful perspectives on the special series.

New Impact Factor for Translational Cancer Research: 1.5

We are pleased to announce that Translational Cancer Research (TCR) has attained its latest impact factor update for the 2023 citation year: 1.5.

Translational Cancer Research 2023 CiteScore Released: 2.1

We are pleased to announce that the Translational Cancer Research (TCR) has received its 2023 CiteScore: 2.1, ranking 209 out of 333 journals in the Radiology, Nuclear Medicine and Imaging category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

Ferroptosis and cuproptosis prognostic signature for prediction of prognosis, immunotherapy and drug sensitivity in hepatocellular carcinoma: development and validation based on TCGA and ICGC databases

Identification of differentially expressed genes. (A) Heatmap revealed differentially expressed genes; (B) univariate Cox regression analysis; (C) a protein-protein interaction network showing the relationship between ferroptosis-related genes and cuproptosis-related genes.

Bartholin’s gland carcinoma—the diagnostic and management challenges of a rare malignancy—a case report and review of current literature

FDG-avid right inguinal lymph node on axial CT-PET. The green arrow: FDG-avid right inguinal lymph node on axial CT-PET. FDG, fluorodeoxyglucose; CT-PET, computed tomography-positron-emission tomography.

Development of a novel angiogenesis-related lncRNA signature to predict the prognosis and immunotherapy of glioblastoma multiforme

Differences in risk scores for clinical characteristics. (A-D) The correlations between the risk score and sex, age, MGMT status, and IDH1 status were not significant (P>0.05). (E) Among the subtypes, the proneural subtypes had a significantly lower risk score than did the mesenchymal subtypes (P<0.05). **, P<0.01. IDH1, isocitrate dehydrogenase 1; MGMT, O6-methylguanine-DNA methyltransferase; ns, no significance.

Integrated analysis of single-cell and bulk transcriptome identifies a signature based on NK cell marker genes to predict prognosis and therapeutic response in clear cell renal cell carcinoma

Single-cell sequencing analysis of 20,074 cells from 7 ccRCC samples. (A) Pearson’s correlation between nFeature and nCount. (B) PCA plot colored by different samples. (C) Cells were classified into 25 clusters via UMAP algorithm. (D) Eight cell types were identified and annotated by marker genes. (E) Heatmap visualized top 5 marker genes among 8 cell clusters. (F) Visualization of gene expression in cell clusters. PC, principal component; UMAP, uniform manifold approximation and projection; NK, nature killer; ccRCC, clear cell renal cell carcinoma; PCA, principal component analysis.

Development and validation of nomograms to predict early death in non-small cell lung cancer patients with brain metastasis: a retrospective study in the SEER database

ROC curves for the nomograms of the all-cause early death and the cancer-specific early death in the training cohort (A,B) as well as in the validation cohort (C,D). ROC, receiver operating characteristic; AUC, area under the curve.

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Vol 14, No 5 (May, 2025)

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Announcement more

Join us at the 33rd Annual Meeting of the European Society of Thoracic Surgery (ESTS)

Join us at the 33rd Annual Meeting of the European Society of Thoracic Surgery (ESTS) More >>

Join us at the 105th Annual Meeting of American Association for Thoracic Surgery (AATS)

The 105th Annual Meeting of American Association for Thoracic Surgery (AATS) is going to be held at the Seattle Convention Center, Seattle, WA, USA from May 2 to 5, 2025: https://e... More >>

TCR 2024 Annual Report

Greetings from the Editorial Office of TCR! More >>

Editorial Commentary

Does circulating DNA tumor fraction add value to prostate-specific antigen in metastatic castration-resistant prostate cancer?

Cora N. Sternberg, Maha Hussain

PDF Pages: 2536-2538 Full Text (11) Peer Review File COI Form Open Access

The promise and translation of cell-free human papillomavirus DNA testing for cervical cancer surveillance

Justin Garland, Kathleen N. Moore, Joan L. Walker, Doris M. Benbrook

PDF Pages: 2539-2543 Full Text (5) Peer Review File COI Form Open Access

“Prime and pull” vaccination strategy for treatment of cervical pre-cancer: not quite ready for prime time

Katherine Cooke, Deanna G. K. Teoh

PDF Pages: 2544-2547 Full Text (3) Peer Review File COI Form Open Access

Novel combinations with programmed cell death 1 inhibitor for incurable recurrent/metastatic head and neck squamous cell carcinoma (RM HNSCC): is cabozantinib a front runner?

Priyanka Bhateja, Marcelo Bonomi, Claire Verschraegen

PDF Pages: 2548-2552 Full Text (4) Peer Review File COI Form Open Access

Microsatellite instability (MSI) and the tumor mutation burden (TMB) as biomarkers of response to immune checkpoint inhibitors in prostate cancer

Ioannis A. Voutsadakis

PDF Pages: 2553-2557 Full Text (3) Peer Review File COI Form Open Access

When is belzutifan the right option for von Hippel-Lindau disease-associated hemangioblastomas?—a critical review of LITESPARK-004 results

Ugur Sener, Taylor Galloway

PDF Pages: 2558-2562 Full Text (3) Peer Review File COI Form Open Access

Original Article

Construction of a prognostic model for lung adenocarcinoma based on necroptosis genes and its exploration of the potential for tumor immunotherapy

Xiaoling Liu, Xin Li, Xiufen Shen, Run Ma, Zhuo Wang, Ying Hu

PDF Pages: 2563-2579 Full Text (8) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Evaluating HSP90AA1 as a predictive biomarker for prognosis in lung adenocarcinoma

Shi Xiang, Wenwen Zhang, Zhichao Wang, Hui Chen, Chao Yang

PDF Pages: 2580-2593 Full Text (10) Reporting Checklist Peer Review File COI Form Open Access

Extracellular vesicles isolated from SphK1 inhibitor SKI II-medium restrain the migration of colorectal cancer

Chunyan Xu, Yingbin Hu, Guodong Dai, Yan Chen, Chengxia Liu

PDF Pages: 2594-2602 Full Text (5) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Ovarian teratomas causing anti-N-methyl-D-aspartate receptor encephalitis: a case series from west China

Jiaxin Gu, Xiumei Xu, Qian Chen, Min Feng, Ruiqi Duan

PDF Pages: 2603-2614 Full Text (3) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Differences in esophageal adenocarcinoma survival and treatment modalities by III/IV stage subgroup: a SEER population-based study

Cheng Gong, Zhidong Wang, Ce Chao, Min Wang, Yongxiang Qian, Dongmei Di, Yang Liu

PDF Pages: 2615-2625 Full Text (3) Reporting Checklist Peer Review File COI Form Open Access

Identification of the MEX3 family as potential biomarkers of hepatocellular carcinoma based on bioinformatics and experiments

Jingrong Xian, Anli Jin, Mi Zhou, Wenqi Shao, Jing Zhu, Baishen Pan, Beili Wang, Wei Guo, Wenjing Yang

PDF Pages: 2626-2647 Full Text (8) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

GJB2 enhances cancer stem cell properties by modulating SOX2 expression via NF-κB pathway activation in lung adenocarcinoma

Qi You, Tao Huang, Zhijie He, Xinlu Tao, Yan Zhang, Haotian Zhang, Shaojin Zhu

PDF Pages: 2648-2660 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Construction and validation of a clinical prognostic model for frontal glioblastoma: a real-world clinical study based on radiation therapy

Shuai Hao, Jialing Liu, Jingjing Tuo, Li Wang, Wei Li, Ming Liu, Pengzhan Shuang, Nan Li

PDF Pages: 2661-2676 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Development of a prognostic model for overall survival in neuroblastoma based on Schwann cell-specific genes, clinical predictors, and MYCN amplification

Zexi Li, Jing Liu, Yurui Wu

PDF Pages: 2677-2689 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Construction and validation of a prognostic model for glioma: an analysis based on mismatch repair-related genes and their correlation with clinicopathological features

Tong Wang, Bohao Sun, Rui Yu, Jing Zhang, Yichen Wu, Delin Wang, Xiaoying Ni, Hao Wang

PDF Pages: 2690-2706 Full Text (3) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Increased expression of RIPOR1 predicts the poor prognosis of colorectal cancer patients

Xiaolei Yue, Junyu Bian, Zhikun Dong, Yonglin Chen

PDF Pages: 2707-2721 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Effect of periplocin on malignant behavior of oral squamous cell carcinoma cells

Qian Zhao, Yueting Lu, Hualin Lu, Dixian Wang, Hongyue Shang, Manman Yao, Tiejun Liu

PDF Pages: 2722-2736 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification of neuronal synapse-related signatures and potential therapeutic drugs in colorectal cancer based on machine learning algorithms and molecular docking

Wen-Jing Wu, Kan Wang, Yang Vivian Yang, Xiaoning Yang

PDF Pages: 2737-2757 Full Text (17) Reporting Checklist Peer Review File COI Form Open Access

Comprehensive assessment of disulfidptosis-related long non-coding RNA index as biomarkers for predicting clinical outcomes and immune microenvironment in pancreatic cancer

Xiangyu Jin, Jinping Yang, Dongjing Li, Wendi Zhang, Qi Zhang, Mengxing Li, Yingquan Ye, Zhaohui Chen

PDF Pages: 2758-2778 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Machine learning-driven prognostic model based on sphingolipid-related gene signature in pancreatic cancer: development and validation

Qi Zou, Hailin Jiang, Qihui Sun, Qian Peng, Jie He, Keping Xie, Fang Wei

PDF Pages: 2779-2796 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Herpes simplex virus-thymidine kinase/ganciclovir suppressed the growth of lung adenocarcinoma cells accompanied by premature senescence

Nan-Xi Yu, Zhi-Hui Li, Qing-Hua Yu, Xue Lu, Ling Gao

PDF Pages: 2797-2807 Full Text (3) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of nomograms for predicting survival of locally advanced rectosigmoid junction cancer patients: a SEER database analysis

Sirui Zhu, Yuncan Xing, Jiawei Tu, Wei Pei, Jianjun Bi, Zhaoxu Zheng, Qiang Feng

PDF Pages: 2808-2821 Full Text (4) Reporting Checklist Peer Review File COI Form Open Access

Development of a prognostic nomogram and risk factor analysis for survival in H. pylori-positive non-cardia gastric adenocarcinoma patients

Jing Wu, Xiancai Du, Wenwen Chen, Ting Ma, Lu Tian, Hong Zhang, Guanhua Wang, Wenjun Yang

PDF Pages: 2822-2834 Full Text (12) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic role of tumor microenvironment and immune- and autophagy-related genes in colorectal adenocarcinoma

Miao Zhang, Wen Jin, Lei Cao, Yanwei Gao, Yongsheng Wang, Jialin Wang

PDF Pages: 2835-2857 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Identification and functional analysis of GNAI1 as a biomarker associated with immune-related genes in pediatric acute myeloid leukemia

Li Liu, Hongping Yang, Yan Zhou, Na Li, Qi Nie, Xinmiao Liu, Chunhui Yang, Xiaoyan Mao, Yue Tian, Qulian Guo, Xin Tian

PDF Pages: 2858-2873 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

CREB3-mediated upregulation of MIR210HG transcription enhances proliferation in colon cancer cells

Xiaoqian Wang, Aqiang Fan, Liu Hong

PDF Pages: 2874-2884 Full Text (5) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Construction and validation of a nomogram prediction model for predicting the risk of chemotherapy-induced myelosuppression after chemotherapy in patients with triple-negative breast cancer: a single-center retrospective case-control study

Haoling Xie, Rong Zhang, Chunmei Wei, Jinsong Xu, Jie Chu, Xuexing Wang

PDF Pages: 2885-2899 Full Text (6) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of prognostic models based on cell cycle-related signatures for predicting the prognosis of patients with lung adenocarcinoma

Yuanping Huang, Yanfei Zhao, Yinghui Guan

PDF Pages: 2900-2915 Full Text (5) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Race, gender, and safety: exposing biases in minimally invasive lung cancer surgery research

Brian Housman, Emanuela Taioli, Shubham Gulati, Raja Flores

PDF Pages: 2916-2925 Full Text (6) Reporting Checklist Peer Review File COI Form Open Access

Overexpression of LINC00880 promotes colorectal cancer growth

Ge Gao, Peiwen Xu, Chunyu Yang, Mengyuan Qian, Qingwen Wang, Surui Yao, Yuan Yin, Zhaohui Huang, Zehua Bian

PDF Pages: 2926-2939 Full Text (6) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

In silico development and validation of a novel six-gene-derived signature in hepatocellular carcinoma

Jin He, Binbin Li, Huize Liu, Weijian Chu, Chunhui Rao

PDF Pages: 2940-2955 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Prognostic value of lactate dehydrogenase to albumin ratio in first-line chemoimmunotherapy for locally advanced or metastatic non-small cell lung cancer

Bohua Wei, Hao Cui, Kun Qian, Kejian Shi, Peilong Zhang, Yi Zhang

PDF Pages: 2956-2965 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Sublobar resection is non-inferior to lobectomy in octogenarians and older with stage Ia non-small cell lung cancer

Chuxu Wang, Yiwei Hu, Bo Min, Zilong Tang, Guodong Hu, Chengxiang Wang, Yaqin Wang, Haibo Hu, Xiaohua Zuo

PDF Pages: 2966-2980 Full Text (2) Reporting Checklist Peer Review File COI Form Open Access

Identification of a novel prognostic gene signature in pleural mesothelioma: a study based on The Cancer Genome Atlas database and experimental validation

Xinmeng Wang, Yongqin Yang, Wenzhong Yang, Xi Yang, Jinsong Li, Yaru Lin, Zhengliang Li, Jiangyan Li, Wei Xiong

PDF Pages: 2981-2998 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Integrated analysis of uterine leiomyosarcoma and leiomyoma utilizing TCGA and GEO data: a WGCNA and machine learning approach

Zixin Yang, Fan Yang, Fanlin Li, Ying Zheng

PDF Pages: 2999-3016 Full Text (4) Reporting Checklist Peer Review File COI Form Open Access

Prognostic significance of IL11RA and its methylation in lung adenocarcinoma

Zhimin Li, Guicheng He, Hui Zeng, Zhen Wang, Hui Yang, Aitao Nai

PDF Pages: 3017-3034 Full Text (7) Reporting Checklist Peer Review File COI Form Open Access

Deep learning for fine-grained molecular-based colorectal cancer classification

Junyu Bian, Yansong Li, Yamei Dang, Yonglin Chen

PDF Pages: 3035-3046 Full Text (6) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The role of radiotherapy in distant nasopharyngeal carcinoma: a SEER analysis

Long Chen, Dun-Chang Mo, Jin-Nian He, Ke-Jiang Du, Li-Ping Peng, Shi-Hua Yin

PDF Pages: 3047-3056 Full Text (5) Reporting Checklist Peer Review File COI Form Open Access

Machine learning and deep learning to improve overall survival prediction in cervical cancer patients

Nan Jiang, Xing Xiong, Xue Chen, Mengmeng Feng, Yan Guo, Chunhong Hu

PDF Pages: 3057-3068 Full Text (8) Reporting Checklist Peer Review File COI Form Open Access

The prognostic and immune significance of fibronectin type III domain-containing 1 gene in pan-cancer and its relationship with proliferation and migration of stomach adenocarcinoma

Minying Deng, Wen Huang, Rongkui Luo, Huimei Wang, Zixiang Yu, Benting Ma, Lei Xu, Xiaolei Zhang, Jieakesu Su, Chen Xu, Yingyong Hou

PDF Pages: 3069-3095 Full Text (3) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Developing a prognostic risk model based on circulating tumor cell genes to predict prognosis and provide potential therapeutic strategies in colorectal cancer

Yupeng Zheng, Mian Yang, Hongyi Yi, Tao Peng, Jiaze Sun, Jiazi Yu

PDF Pages: 3096-3112 Full Text (3) Reporting Checklist Peer Review File COI Form Open Access

Identification and validation of hypoxia-associated genes positively correlated with HIF1A in pulmonary adenocarcinoma

Haifeng Zhu, Yun Wang, Zunyu Chen, Ruonan Guo, Xiaobai Wu, Yifan Jiang, Yang Shu, Hanpeng Huang

PDF Pages: 3113-3132 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis

Ansu Li, Wu Sun, Shihe Shao, Xuefeng Qiu, Jianpeng Hu, Feilun Cui

PDF Pages: 3133-3148 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Ubiquitin-specific peptidase 20 affects immune cell infiltration by regulating prostaglandin E2 on intraperitoneal metastasis model of colorectal cancer

Yang Hua, Xiukun Ma, Xinyu Zhao, Xiaomeng Wei, Xiaojing Mu, Botao Wang, Xiangfei Yuan

PDF Pages: 3149-3160 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A real-world retrospective cohort study: the clinical outcomes and characteristics of platinum-resistant recurrent ovarian cancer

Qing Wang, Lei Kuang, Boyang Liu, Qi Chen, Yanyu Li, Jiayun Zhou, Jingbo Zhang, Xinhui Yang, Guiping Wan, Jörg Wischhusen, Rosa A. Salcedo-Hernández, Colton Ladbury, Zeyuan Yin, Bei Zhang

PDF Pages: 3161-3174 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma

Zhihao Li, Hui Xu, Hao Chen, Liang Chen, Hong Zang, Yi Qian

PDF Pages: 3175-3185 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Plasma-derived exosomal human epidermal growth factor receptor 2 (HER2) protein for distinguishing breast cancer from benign breast disease and assessing the efficacy of neoadjuvant therapy

Xiaofang Yang, Mengdan Xu, Yu Xia, Zhaofen Ba, Chunmiao Han, Yipu Wang, Jinwen Qu, Yu Wang, Yehui Zhou, Rong Wang, Jing Lan

PDF Pages: 3186-3200 Full Text (5) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Immunocytochemical staining for p16, Ki-67, and MCM2 in the detection of cervical lesions and cancer: a prospective observational study

Yunyue Liu, Liang Wen, Lingjie Jiang, Jia Xu, Yuanguang Meng, Wen Yang

PDF Pages: 3201-3211 Full Text (4) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Significant weight gain benefits of nanocrystalline megestrol acetate for patients with cancer anorexia-cachexia syndrome

Xue Cheng, Kang Pan, Qing Li, Xin Jin, Chengsong Cao, Yong Liu

PDF Pages: 3212-3225 Full Text (6) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Sphingosine kinase 1 facilitates gastric cancer progression via STAT1 gene methylation-mediated mechanisms

Yunfei Wang, Fei Wang, Bingxi Zhou, Jia Lu, Jiabei Xie, Lijie Yuan, Shuangyin Han

PDF Pages: 3226-3238 Full Text (10) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

Ovarian cancer and malnutrition: a literature review

Zhuyan Shao, Liying Fu, Yi Lu, Haifei Zhou, Yuyang Zhu, Tao Zhu

PDF Pages: 3239-3254 Full Text (7) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Endobronchial malignancy as a manifestation of advanced ovarian cancer recurrence: a case report and literature review

Dongrui Zhang, Li Yang, Alexandros Laios, Wei Jia

PDF Pages: 3255-3262 Full Text (2) Reporting Checklist Peer Review File COI Form Open Access

Erratum

Erratum: The prognostic significance of fragile X mental retardation syndrome-related protein 1 (FXR1) in breast cancer

Editorial Office

PDF Pages: 3263 Full Text (3) Open Access

Erratum: Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway

Editorial Office

PDF Pages: 3264-3269 Full Text (5) Open Access

Retraction

Retraction: TGF-β signaling proteins and CYP24A1 may serve as surrogate markers for progesterone calcitriol treatment in ovarian and endometrial cancers of different histological types

Editorial Office

PDF Pages: 3270 Full Text (7) Open Access

Retraction: H19/miR-152-3p/TCF4 axis increases chemosensitivity of gastric cancer cells through suppression of epithelial-mesenchymal transition

Xiaodong Jiang, Wenbin Ding, Weiguang Shen, Jie Jin

PDF Pages: 3271 Full Text (9) COI Form Open Access

Review Article

The management of brain necrosis as a result of SRS treatment for intra-cranial tumors

Uresh Patel, Ankush Patel, Charles Cobb, Tara Benkers, Sandra Vermeulen

Published online: 28 August 2014

PDF Pages: 373-382 Full Text (128778) COI Form Open Access

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis

Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Published online: 05 March 2013

PDF Pages: 25-32 Full Text (77731) COI Form Open Access

Review Article

Common applications of next-generation sequencing technologies in genomic research

Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Published online: 05 March 2013

PDF Pages: 33-45 Full Text (68697) COI Form Open Access

Biological basis of IORT

Immune effects of high dose radiation treatment: implications of ionizing radiation on the development of bystander and abscopal effects

Ithaisa Sologuren, Carlos Rodríguez-Gallego, Pedro Carlos Lara

Published online: 25 February 2014

PDF Pages: 18-31 Full Text (48801) COI Form Open Access

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Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer

Deep Kwatra, Anand Venugopal, Shrikant Anant

Published online: 26 September 2013

PDF Pages: 330-342 Full Text (47736) COI Form Open Access

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Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer

Rositsa Dueva, George Iliakis

Published online: 19 June 2013

PDF Pages: 163-177 Full Text (47525) COI Form Open Access

Original Article

Effect of fasting therapy in chemotherapy-protection and tumorsuppression: a systematic review

Lei Sun, Yong-Jiang Li, Xi Yang, Ling Gao, Cheng Yi

Published online: 28 April 2017

PDF Pages: 354-365 Full Text (47172) COI Form Open Access

Editorial

Morphine, when used for treating patients with acute pancreatitis, could be more risky than previously suspected

Juan Iovanna, Maria Cecilia Mallmann

Published online: 24 October 2017

PDF Pages: S1166-S1168 Full Text (45838) COI Form Open Access

Review Article

EGFR first- and second-generation TKIs—there is still place for them in EGFR-mutant NSCLC patients

Niki Karachaliou, Manuel Fernandez-Bruno, Jillian Wilhelmina Paulina Bracht, Rafael Rosell

Published online: 19 January 2019

PDF Pages: S23-S47 Full Text (39325) COI Form Open Access

Review Article

Do alkaline phosphatases have great potential in the diagnosis, prognosis, and treatment of tumors?

Tingting Jiang, Qun Zeng, Jun He

Published online: 20 October 2023

PDF Pages: 2932-2945 Full Text (37957) Peer Review File COI Form Open Access

Review Article

Cancer biomarker discovery and validation

Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida

Published online: 18 June 2015

PDF Pages: 256-269 Full Text (37738) COI Form Open Access

Review Articles

Tumor microenvironment and nanotherapeutics

Meenakshi Upreti, Amar Jyoti, Pallavi Sethi

Published online: 26 September 2013

PDF Pages: 309-319 Full Text (37657) COI Form Open Access

Biological basis of IORT

Cell and molecular response to IORT treatment

Luigi Minafra, Valentina Bravatà

Published online: 25 February 2014

PDF Pages: 32-47 Full Text (35877) COI Form Open Access

Editorial

The CROSS road in neoadjuvant therapy for esophageal cancer: long-term results of CROSS trial

Ian Wong, Simon Law

Published online: 29 September 2016

PDF Pages: S415-S419 Full Text (32316) COI Form Open Access

Review Articles

DNA damage tolerance: a double-edged sword guarding the genome

Gargi Ghosal, Junjie Chen

Published online: 19 June 2013

PDF Pages: 107-129 Full Text (29723) COI Form Open Access

Review Articles

DNA crosslinking damage and cancer - a tale of friend and foe

Yaling Huang, Lei Li

Published online: 19 June 2013

PDF Pages: 144-154 Full Text (29506) COI Form Open Access

Review Article

Multiple keratoacanthoma centrifugum marginatum—a case report and systematic review

Yiman Wang, Wenling Zhao, Yueping Zeng, Li Li, Hongzhong Jin

Published online: 30 December 2018

PDF Pages: 1743-1747 Full Text (28833) COI Form Open Access

Review Articles

MDM2 and MDMX: alone and together in regulation of p53

Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan

Published online: 01 August 2012

PDF Pages: 88-99 Full Text (28476) COI Form Open Access

Review Article

EGFR and HER2: is there a role in ovarian cancer?

Eleonora Teplinsky, Franco Muggia

Published online: 13 February 2015

PDF Pages: 107-117 Full Text (28499) COI Form Open Access

Original Article

Intraoperative radiotherapy in locally-advanced and recurrent rectal cancer: retrospective review of 68 cases

Sergey Potemin, Ivan Uvarov, Igor Vasilenko

Published online: 26 April 2015

PDF Pages: 189-195 Full Text (28027) COI Form Open Access

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How are lung cancer risk perceptions and cigarette smoking related?—testing an accuracy hypothesis

Lei-Shih Chen, Kimberly A. Kaphingst, Tung-Sung Tseng, Shixi Zhao

Alcohol intake patterns for cancer and non-cancer individuals: a population study

Hui-Yi Lin, Paige Fisher, Darian Harris, Tung-Sung Tseng

Application of Bayesian predictive probability for interim futility analysis in single-arm phase II trial

Dung-Tsa Chen, Michael J. Schell, William J. Fulp, Fredrik Pettersson, Sungjune Kim, Jhanelle E. Gray, Eric B. Haura

Review Article

Integrative clustering methods for high-dimensional molecular data

Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley

Sparse principal component analysis in cancer research

Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen

An improved understanding of cancer genomics through massively parallel sequencing

Jamie K. Teer

Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications

Louis Dubeau

Cancer biomarker discovery and validation

Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida

The promise and challenge of ovarian cancer models

Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Prostate cancer: unmet clinical needs and RAD9 as a candidate biomarker for patient management

Howard B. Lieberman, Alex J. Rai, Richard A. Friedman, Kevin M. Hopkins, Constantinos G. Broustas

Exosomal lncRNAs as new players in cell-to-cell communication

Mihnea Dragomir, Baoqing Chen, George A. Calin

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy

Souparno Bhattacharya, Aroumougame Asaithamby

Translational research in radiation-induced DNA damage signaling and repair

Jac A. Nickoloff, Mary-Keara Boss, Christopher P. Allen, Susan M. LaRue

Genetically engineered mouse models for studying radiation biology

Katherine D. Castle, Mark Chen, Amy J. Wisdom, David G. Kirsch

Renal cell carcinoma: the search for a reliable biomarker

Nicholas J. Farber, Christopher J. Kim, Parth K. Modi, Jane D. Hon, Evita T. Sadimin, Eric A. Singer

Advances on immunotherapy in genitourinary and renal cell carcinoma

Gregory P. Botta, Eric Granowicz, Carrie Costantini

The role of novel immunotherapies in non-Hodgkin lymphoma

Allyson Pishko, Sunita D. Nasta

MDMX under stress: the MDMX-MDM2 complex as stress signals hub

Anna de Polo, Varunika Vivekanandan, John B. Little, Zhi-Min Yuan

Do p53 stress responses impact organismal aging?

Paul Hasty, Judith Campisi, Z. Dave Sharp

Pharmacological targeting of mutant p53

Samuel Kogan, Darren Carpizo

Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis

Michael I. Carr, Stephen N. Jones

Regulation of cytotoxic T-cell responses by p53 in cancer

Mitchell W. Braun, Tomoo Iwakuma

The IGF-1R/AKT pathway determines cell fate in response to p53

Lei Duan, Carl G. Maki

Intra molecular interactions in the regulation of p53 pathway

Jiandong Chen

TP53 mutations in epithelial ovarian cancer

Yu Zhang, Lan Cao, Daniel Nguyen, Hua Lu

Modulation of the p53 family network by RNA-binding proteins

Chris Lucchesi, Jin Zhang, Xinbin Chen

Radiomics in head and neck cancer: from exploration to application

Andrew J. Wong, Aasheesh Kanwar, Abdallah S. Mohamed, Clifton D. Fuller

Prostate cancer radiomics and the promise of radiogenomics

Radka Stoyanova, Mandeep Takhar, Yohann Tschudi, John C. Ford, Gabriel Solórzano, Nicholas Erho, Yoganand Balagurunathan, Sanoj Punnen, Elai Davicioni, Robert J. Gillies, Alan Pollack

Positron emission tomography/computerized tomography for tumor response assessment—a review of clinical practices and radiomics studies

Wei Lu, Wengen Chen

The emerging field of radiomics in esophageal cancer: current evidence and future potential

Peter SN. van Rossum, Cai Xu, David V. Fried, Lucas Goense, Laurence E. Court, Steven H. Lin

Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat’s in the fire

Jung H. Suh, Julie D. Saba

Computational methods and opportunities for phosphorylation network medicine

Yian Ann Chen, Steven A. Eschrich

Editorial

Focusing in on radiation induced brain injury

M. Kerry O’Banion

Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic

Naomi Lomeli, Daniela A. Bota

Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma

David C. Binder, Erik Ladomersky, Alicia Lenzen, Lijie Zhai, Kristen L. Lauing, Sebastian D. Otto-Meyer, Rimas V. Lukas, Derek A. Wainwright

New light on the pancreatic cyst conundrum

Nathan A. Berger

HNF1A, KRT81, and CYP3A5: three more straws on the back of pancreatic cancer?

Andrew J. Scott, John C. Wilkinson

Bevacizumab as an adjuvant therapy for glioblastoma in elderly patients: the facts

Kristopher A. Lyon, Jason H. Huang

Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4

Nan Ding, Qianzheng Zhu

Hypofractionated whole breast irradiation is cost-effective—but is that enough to change practice?

Apar Gupta, Nisha Ohri, Bruce G. Haffty

Cost-effectiveness in managing skeletal related events in breast cancer: a strategy of less-intense dosing schedule of bone modifying agents

Sri Harsha Tella, Anuhya Kommalapati, Ryan K. Singhi

CRISPR-based genetic interaction maps inform therapeutic strategies in cancer

Poornima Ramkumar, Martin Kampmann

Smooth sailing for immunotherapy for unresectable stage III nonsmall cell lung cancer: the PACIFIC study

Melin J. Khandekar, Rakesh Jain

The evolving role of molecular profiling in prostate cancer: basal and luminal subtyping transcends tissue of origin

Omar Y. Mian, Rahul D. Tendulkar, Mohamed E. Abazeed

Serrated polyposis: the problem of definition and its relationship to the population at risk for syndrome-related colorectal cancer

Joanne P. Young, Timothy J. Price, Susan Parry

Multifactorial regulators of tumor programmed death-ligand 1 (PD-L1) response

R. Dixon Dorand, Agne Petrosiute, Alex Y. Huang

Therapeutic targeting of oncogenic KRAS in pancreatic cancer by engineered exosomes

Theresa L. Whiteside

TIC10/ONC201—a potential therapeutic in glioblastoma

Georg Karpel-Massler, Markus D. Siegelin

IDH mutational status and the immune system in gliomas: a tale of two tumors?

Bryan D. Choi, William T. Curry

ONC201: a new treatment option being tested clinically for recurrent glioblastoma

Marie D. Ralff, Amriti R. Lulla, Jessica Wagner, Wafik S. El-Deiry

When better still might not be good enough

Waldemar Debinski

Androgen receptor antagonism and impact on inhibitors of androgen synthesis in prostate cancer therapy

Vincent C. O. Njar

Co-inhibitory receptor programmed cell death protein 1 targets co-stimulatory CD28

Leonardo Chicaybam, Prasad S. Adusumilli

Exosome mediated phenotypic changes in lung cancer pathophysiology

Yoshihisa Shimada, John D. Minna

Signatures of field cancerization: a step towards earlier detection of esophageal adenocarcinoma

Aaron D. DeWard, Rebecca J. Critchley-Thorne

From tumorigenesis to microenvironment and immunoregulation: the many faces of focal adhesion kinase and challenges associated with targeting this elusive protein

Felicia L. Lenzo, William G. Cance

New incriminating evidence against IGF2

Wen Ding, Lina A. Shehadeh

Targeting cancer with tumor-specific therapeutic strategies—metabolic reprogramming beyond the Warburg effect

Paul Grippo, Ajay V. Maker

Branched chain amino acid metabolism and cancer: the importance of keeping things in context

Elizabeth M. Selwan, Aimee L. Edinger

RIPK1-TRAF2 interplay on the TNF/NF-κB signaling, cell death, and cancer development in the liver

Satomi Yamamoto, Tomoo Iwakuma

Genome-based modeling for adjusting radiotherapy dose (GARD)-a significant step toward the future of personalized radiation therapy

Michael J. Baine, Chi Lin

Rogue one: another faction of the Wnt empire implicated in assisting GBM progression

Riasat Ahsan, Shivani Baisiwala, Atique U. Ahmed

Normalizing tumoral vessels to treat cancer: an out-of-the-box strategy involving TIE2 pathway

Juan Fueyo, Mohammad B. Hossain, Teresa Nguyen, Candelaria Gomez-Manzano

Exploring gold nanoparticle interactions with proteins and the tumor microenvironment in biological systems

Li Tian, Ashley Chang, Marites P. Melancon

IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm

James P. White

Low-frequency ultrasound may improve drug penetration in colonic mucosa

Qiubing Chen, Bo Xiao, Didier Merlin

Dividing and conquering the variation among variants in EML4-ALK lung cancer

Trever G. Bivona

Unlocking the epigenetic code of T cell exhaustion

Jiazhu Wu, Huidong Shi

KDM1 links nuclear GSK3β to epigenetic alterations

Weijie Guo, Binhua P. Zhou

Moving the mountain in advanced non-small-cell lung cancer: evolving immunotherapies for a dire disease

Deepa Rangachari, Daniel B. Costa

Taming immune suppressor: application of myeloid-derived suppressor cells in anti-cancer gene therapy

Bhagelu R. Achyut, Ali S. Arbab

Neuroendocrine differentiation in prostate cancer: key epigenetic players

Karishma Gupta, Sanjay Gupta

PD-L1 is a diverse molecule regulating both tumor-intrinsic signaling and adaptive immunosuppression

Kim A. Brogden, Shireen Vali, Taher Abbasi

Mesenchymal stromal cells and interferon α (IFNα) in cancer immunotherapy

Diana Saleiro, Sara G. Radecki, Leonidas C. Platanias

The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Keith T. Schmidt, William D. Figg

Information-dense analysis for information-dense understanding

Nikola A. Ivica, Mandeep Kaur, Guangan Hu, Jianzhu Chen

The “liquid biopsy” in non-small cell lung cancer—not quite ready for prime time use

Angel Qin, Nithya Ramnath

Immune infiltration, glioma stratification, and therapeutic implications

Manny D. Bacolod, Sarmistha Talukdar, Luni Emdad, Swadesh K. Das, Devanand Sarkar, Xiang-Yang Wang, Francis Barany, Paul B. Fisher

Balancing redox stress: anchorage-independent growth requires reductive carboxylation

Clint.A Stalnecker, Ahmad.A Cluntun, Richard.A Cerione

Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy

Fabiana Perna, Michel Sadelain

Harnessing protein kinase A activation to induce mesenchymal-epithelial programs to eliminate chemoresistant, tumor-initiating breast cancer cells

Alex J. Gooding, William P. Schiemann

Actionable intelligence provided by pancreatic cancer genomic landscape: are targets for curative therapy on the map?

Nathan A. Berger

Microtubule targeting agents in glioma

Anda-Alexandra Calinescu, Maria G. Castro

Moving molecular subtypes to the clinic in gastric cancer

Joseph Chao, Jeeyun Lee, Samuel J. Klempner

Intraoperative subtyping of lung adenocarcinoma: an unmet need

Nurlan Aliyev, Yusuke Takahashi, Shaohua Lu, Marissa Mayor, Prasad S. Adusumilli

Emerging roles of FGF signaling in hepatocellular carcinoma

Nana Zheng, Wenyi Wei, Zhiwei Wang

Tregs, Helios and tumor immunity: the sun has not yet risen

Angela M. Thornton, Ethan M. Shevach

Immune checkpoint regulator: a new assignment proposed for the classic adhesion molecule P-selectin glycoprotein ligand-1

Jiaxuan Chen, Carolyn A. Haller, Elliot L. Chaikof

Sarcomatoid renal cell carcinoma: genomic insights from sequencing of matched sarcomatous and carcinomatous components

Brandon J. Manley, James J. Hsieh

Multimodal action of ONECUT2 in driving neuroendocrine prostate cancer

Salma Kaochar, Nicholas Mitsiades

Letter to the Editor

Epigenetic regulation of PD-L1 expression and pancreatic cancer response to checkpoint immunotherapy

Chunwan Lu, Kebin Liu

Synthetic lethality vs. synthetic viability due to PARP1 and BRCA2 loss

Xia Ding, Shyam K. Sharan

Correspondence

Targeted attack: mechanisms by which ovarian cancers suppress the immune system

Irina V. Tiper, Tonya J. Webb

Brief Report

The impact of neighborhood disadvantage on health-related quality of life among African American and white cancer survivors

Chien-Ching Li, Alicia K. Matthews, Anjali Asthana, Raj C. Shah

Research Highlight

Butyrate consumption of differentiated colonocytes in the upper crypt promotes homeostatic proliferation of stem and progenitor cells near the crypt base

Scott J. Bultman

Commentary

Molecular heterogeneity of localized prostate cancer: more different than alike

Jeffrey J. Tosoian, Emmanuel S. Antonarakis

A crowded, but still varied, space: brigatinib in anaplastic lymphoma kinase-rearranged non-small cell lung cancer

Sawsan Rashdan, David E. Gerber

MOAP-1, UBR5 and cisplatin resistance in ovarian cancer

Scott T. Eblen, Amber Bradley

Exportin 1/chromosome region maintenance 1 as a therapeutic target for lung cancer

Weimin Gao

The role of tumor-derived exosomes in epithelial mesenchymal transition (EMT)

Theresa L. Whiteside

[¹⁸F]-choline PET/CT as an imaging biomarker for primary liver cancers

Zhenghong Lee

Empiric H. pylori therapy—10-day concomitant, bismuth quadruple or 14-day triple therapy: none is best

Yoshio Yamaoka, David Y. Graham

JAK3-mediated phosphorylation of EZH2: a novel mechanism of non-canonical EZH2 activation and oncogenic function

Theodoros Karantanos, Vassiliki A. Boussiotis

Cisplatin, etoposide, and irinotecan for relapsed small-cell lung cancer

Angel Qin, Gregory P. Kalemkerian

Helicobacter pylori vacuolating cytotoxin and gastric cancer risk: reconsidered

Muhammad Miftahussurur, Yoshio Yamaoka, David Y. Graham

Colonic crypts are natural gatekeepers of microbial metabolites to protect stem cells

Praveen Kumar Vemula, Venkatakrishna Rao Jala

Helios—controller of Treg stability and function

Claire Chougnet, David Hildeman

Directing abiraterone metabolism: balancing the scales between clinical relevance and experimental observation

Jon K. Obst, Marianne D. Sadar

Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase

Pawel K. Mazur, Or Gozani, Julien Sage, Nicolas Reynoird

Fat lure: adipocytes attract cancer cells out of the prostate

Alexandra M. Blee, Haojie Huang

Impact of genomic heterogeneity associated with acquired anti-EGFR resistance in colorectal cancers

Guoli Chen, Ming-Tseh Lin

Editorials

Into the eye of the storm: breast cancer’s somatic mutation landscape points to DNA damage and repair

Joanne Ngeow, Emily Nizialek, Charis Eng

Perspective

Circular RNAs and competing endogenous RNA (ceRNA) networks

Apratim Mitra, Karl Pfeifer, Ki-Sun Park

The STAMPEDE trial: paradigm-changing data through innovative trial design

Bradley C. Carthon, Emmanuel S. Antonarakis

Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway

Derek B. Oien, Jeremy Chien, Nikki Cheng

Feed your gut with caution!

Vishal Singh, Beng San Yeoh, Matam Vijay-Kumar

Precision oncology: identifying predictive biomarkers for the treatment of metastatic renal cell carcinoma

Parth K. Modi, Nicholas J. Farber, Eric A. Singer

Letter to the Editors

Multiscale modeling of glioblastoma

Huaming Yan, Mónica Romero-López, Lesly I. Benitez, Kaijun Di, Hermann B. Frieboes, Christopher C. W. Hughes, Daniela A. Bota, John S. Lowengrub

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients

Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Review Articles

New developments in treatment planning and verification of particle beam therapy

Reinhard W. Schulte, Andrew J. Wroe

Externally modulated theranostic nanoparticles

Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi

Intestinal stem cell injury and protection during cancer therapy

Jian Yu

Cancer stem cells in glioma: challenges and opportunities

Jialiang Wang, Yufang Ma, Michael K. Cooper

Tumor microenvironment and nanotherapeutics

Meenakshi Upreti, Amar Jyoti, Pallavi Sethi

Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury

Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis

Chang-Lung Lee, Jordan M. Blum, David G. Kirsch

DNA ligases as therapeutic targets

Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest

DNA damage tolerance: a double-edged sword guarding the genome

Gargi Ghosal, Junjie Chen

DNA double strand break repair via non-homologous end-joining

Anthony J. Davis, David J. Chen

DNA crosslinking damage and cancer - a tale of friend and foe

Yaling Huang, Lei Li

Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation

Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan

MDM2 and MDMX: alone and together in regulation of p53

Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan

Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase

Lijian Shao, Lixian Wu, Daohong Zhou

Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment

Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen

SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis

Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos

Normal tissue protection for improving radiotherapy: where are the Gaps?

Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman

Improving chemoradiotherapy with nanoparticle therapeutics

Michael Joseph Eblan, Andrew Zhuang Wang

Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization

Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn

Molecular mechanisms involved in tumor repopulation after radiotherapy

Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li

Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules

Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy

Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar

Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma

Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

Below are the latest Translational Cancer Research articles published online ahead of print publication.

Original Article

Integrated single-cell and bulk RNA sequencing reveals prognostic and immunotherapy-associated myofibroblastic cancer-associated fibroblast subtypes in head and neck squamous cell carcinoma

Xiufang Qiu, Yuhao Lin, Qian Li, Ameya A. Asarkar, Zhiheng Ke, Yiying Xu, Lisha Chen

Published online: 29 May 2025

Journal highlight more

Translational Cancer Research is an international, open access, peer-reviewed journal indexed in Scopus and Science Citation Index Expanded (SCIE), focusing on original, science-based researches on clinical, basic and translational aspects. It publishes laboratory studies of novel therapeutic interventions, clinical trials which evaluate new treatment paradigms for cancer, results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of cancer patients and etc.