Vol 14, No 5 (May 30, 2025): Translational Cancer Research

Editorial Commentary

Does circulating DNA tumor fraction add value to prostate-specific antigen in metastatic castration-resistant prostate cancer?
Cora N. Sternberg, Maha Hussain
PDF Pages: 2536-2538 Full Text (17) Peer Review File COI Form Open Access Get Permission
The promise and translation of cell-free human papillomavirus DNA testing for cervical cancer surveillance
Justin Garland, Kathleen N. Moore, Joan L. Walker, Doris M. Benbrook
PDF Pages: 2539-2543 Full Text (13) Peer Review File COI Form Open Access Get Permission
“Prime and pull” vaccination strategy for treatment of cervical pre-cancer: not quite ready for prime time
Katherine Cooke, Deanna G. K. Teoh
PDF Pages: 2544-2547 Full Text (6) Peer Review File COI Form Open Access Get Permission
Novel combinations with programmed cell death 1 inhibitor for incurable recurrent/metastatic head and neck squamous cell carcinoma (RM HNSCC): is cabozantinib a front runner?
Priyanka Bhateja, Marcelo Bonomi, Claire Verschraegen
PDF Pages: 2548-2552 Full Text (7) Peer Review File COI Form Open Access Get Permission
Microsatellite instability (MSI) and the tumor mutation burden (TMB) as biomarkers of response to immune checkpoint inhibitors in prostate cancer
Ioannis A. Voutsadakis
PDF Pages: 2553-2557 Full Text (9) Peer Review File COI Form Open Access Get Permission
When is belzutifan the right option for von Hippel-Lindau disease-associated hemangioblastomas?—a critical review of LITESPARK-004 results
Ugur Sener, Taylor Galloway
PDF Pages: 2558-2562 Full Text (6) Peer Review File COI Form Open Access Get Permission

Original Article

Construction of a prognostic model for lung adenocarcinoma based on necroptosis genes and its exploration of the potential for tumor immunotherapy
Xiaoling Liu, Xin Li, Xiufen Shen, Run Ma, Zhuo Wang, Ying Hu
PDF Pages: 2563-2579 Full Text (16) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Evaluating HSP90AA1 as a predictive biomarker for prognosis in lung adenocarcinoma
Shi Xiang, Wenwen Zhang, Zhichao Wang, Hui Chen, Chao Yang
PDF Pages: 2580-2593 Full Text (21) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Extracellular vesicles isolated from SphK1 inhibitor SKI II-medium restrain the migration of colorectal cancer
Chunyan Xu, Yingbin Hu, Guodong Dai, Yan Chen, Chengxia Liu
PDF Pages: 2594-2602 Full Text (13) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Ovarian teratomas causing anti-N-methyl-D-aspartate receptor encephalitis: a case series from west China
Jiaxin Gu, Xiumei Xu, Qian Chen, Min Feng, Ruiqi Duan
PDF Pages: 2603-2614 Full Text (10) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Differences in esophageal adenocarcinoma survival and treatment modalities by III/IV stage subgroup: a SEER population-based study
Cheng Gong, Zhidong Wang, Ce Chao, Min Wang, Yongxiang Qian, Dongmei Di, Yang Liu
PDF Pages: 2615-2625 Full Text (6) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification of the MEX3 family as potential biomarkers of hepatocellular carcinoma based on bioinformatics and experiments
Jingrong Xian, Anli Jin, Mi Zhou, Wenqi Shao, Jing Zhu, Baishen Pan, Beili Wang, Wei Guo, Wenjing Yang
PDF Pages: 2626-2647 Full Text (13) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
GJB2 enhances cancer stem cell properties by modulating SOX2 expression via NF-κB pathway activation in lung adenocarcinoma
Qi You, Tao Huang, Zhijie He, Xinlu Tao, Yan Zhang, Haotian Zhang, Shaojin Zhu
PDF Pages: 2648-2660 Full Text (17) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Construction and validation of a clinical prognostic model for frontal glioblastoma: a real-world clinical study based on radiation therapy
Shuai Hao, Jialing Liu, Jingjing Tuo, Li Wang, Wei Li, Ming Liu, Pengzhan Shuang, Nan Li
PDF Pages: 2661-2676 Full Text (10) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Development of a prognostic model for overall survival in neuroblastoma based on Schwann cell-specific genes, clinical predictors, and MYCN amplification
Zexi Li, Jing Liu, Yurui Wu
PDF Pages: 2677-2689 Full Text (9) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Construction and validation of a prognostic model for glioma: an analysis based on mismatch repair-related genes and their correlation with clinicopathological features
Tong Wang, Bohao Sun, Rui Yu, Jing Zhang, Yichen Wu, Delin Wang, Xiaoying Ni, Hao Wang
PDF Pages: 2690-2706 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Increased expression of RIPOR1 predicts the poor prognosis of colorectal cancer patients
Xiaolei Yue, Junyu Bian, Zhikun Dong, Yonglin Chen
PDF Pages: 2707-2721 Full Text (16) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Effect of periplocin on malignant behavior of oral squamous cell carcinoma cells
Qian Zhao, Yueting Lu, Hualin Lu, Dixian Wang, Hongyue Shang, Manman Yao, Tiejun Liu
PDF Pages: 2722-2736 Full Text (12) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Identification of neuronal synapse-related signatures and potential therapeutic drugs in colorectal cancer based on machine learning algorithms and molecular docking
Wen-Jing Wu, Kan Wang, Yang Vivian Yang, Xiaoning Yang
PDF Pages: 2737-2757 Full Text (29) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Comprehensive assessment of disulfidptosis-related long non-coding RNA index as biomarkers for predicting clinical outcomes and immune microenvironment in pancreatic cancer
Xiangyu Jin, Jinping Yang, Dongjing Li, Wendi Zhang, Qi Zhang, Mengxing Li, Yingquan Ye, Zhaohui Chen
PDF Pages: 2758-2778 Full Text (10) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Machine learning-driven prognostic model based on sphingolipid-related gene signature in pancreatic cancer: development and validation
Qi Zou, Hailin Jiang, Qihui Sun, Qian Peng, Jie He, Keping Xie, Fang Wei
PDF Pages: 2779-2796 Full Text (9) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Herpes simplex virus-thymidine kinase/ganciclovir suppressed the growth of lung adenocarcinoma cells accompanied by premature senescence
Nan-Xi Yu, Zhi-Hui Li, Qing-Hua Yu, Xue Lu, Ling Gao
PDF Pages: 2797-2807 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Development and validation of nomograms for predicting survival of locally advanced rectosigmoid junction cancer patients: a SEER database analysis
Sirui Zhu, Yuncan Xing, Jiawei Tu, Wei Pei, Jianjun Bi, Zhaoxu Zheng, Qiang Feng
PDF Pages: 2808-2821 Full Text (8) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Development of a prognostic nomogram and risk factor analysis for survival in H. pylori-positive non-cardia gastric adenocarcinoma patients
Jing Wu, Xiancai Du, Wenwen Chen, Ting Ma, Lu Tian, Hong Zhang, Guanhua Wang, Wenjun Yang
PDF Pages: 2822-2834 Full Text (16) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Prognostic role of tumor microenvironment and immune- and autophagy-related genes in colorectal adenocarcinoma
Miao Zhang, Wen Jin, Lei Cao, Yanwei Gao, Yongsheng Wang, Jialin Wang
PDF Pages: 2835-2857 Full Text (10) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification and functional analysis of GNAI1 as a biomarker associated with immune-related genes in pediatric acute myeloid leukemia
Li Liu, Hongping Yang, Yan Zhou, Na Li, Qi Nie, Xinmiao Liu, Chunhui Yang, Xiaoyan Mao, Yue Tian, Qulian Guo, Xin Tian
PDF Pages: 2858-2873 Full Text (11) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
CREB3-mediated upregulation of MIR210HG transcription enhances proliferation in colon cancer cells
Xiaoqian Wang, Aqiang Fan, Liu Hong
PDF Pages: 2874-2884 Full Text (11) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Construction and validation of a nomogram prediction model for predicting the risk of chemotherapy-induced myelosuppression after chemotherapy in patients with triple-negative breast cancer: a single-center retrospective case-control study
Haoling Xie, Rong Zhang, Chunmei Wei, Jinsong Xu, Jie Chu, Xuexing Wang
PDF Pages: 2885-2899 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Development and validation of prognostic models based on cell cycle-related signatures for predicting the prognosis of patients with lung adenocarcinoma
Yuanping Huang, Yanfei Zhao, Yinghui Guan
PDF Pages: 2900-2915 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Race, gender, and safety: exposing biases in minimally invasive lung cancer surgery research
Brian Housman, Emanuela Taioli, Shubham Gulati, Raja Flores
PDF Pages: 2916-2925 Full Text (9) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Overexpression of LINC00880 promotes colorectal cancer growth
Ge Gao, Peiwen Xu, Chunyu Yang, Mengyuan Qian, Qingwen Wang, Surui Yao, Yuan Yin, Zhaohui Huang, Zehua Bian
PDF Pages: 2926-2939 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
In silico development and validation of a novel six-gene-derived signature in hepatocellular carcinoma
Jin He, Binbin Li, Huize Liu, Weijian Chu, Chunhui Rao
PDF Pages: 2940-2955 Full Text (8) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Prognostic value of lactate dehydrogenase to albumin ratio in first-line chemoimmunotherapy for locally advanced or metastatic non-small cell lung cancer
Bohua Wei, Hao Cui, Kun Qian, Kejian Shi, Peilong Zhang, Yi Zhang
PDF Pages: 2956-2965 Full Text (8) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Sublobar resection is non-inferior to lobectomy in octogenarians and older with stage Ia non-small cell lung cancer
Chuxu Wang, Yiwei Hu, Bo Min, Zilong Tang, Guodong Hu, Chengxiang Wang, Yaqin Wang, Haibo Hu, Xiaohua Zuo
PDF Pages: 2966-2980 Full Text (9) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification of a novel prognostic gene signature in pleural mesothelioma: a study based on The Cancer Genome Atlas database and experimental validation
Xinmeng Wang, Yongqin Yang, Wenzhong Yang, Xi Yang, Jinsong Li, Yaru Lin, Zhengliang Li, Jiangyan Li, Wei Xiong
PDF Pages: 2981-2998 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Integrated analysis of uterine leiomyosarcoma and leiomyoma utilizing TCGA and GEO data: a WGCNA and machine learning approach
Zixin Yang, Fan Yang, Fanlin Li, Ying Zheng
PDF Pages: 2999-3016 Full Text (7) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Prognostic significance of IL11RA and its methylation in lung adenocarcinoma
Zhimin Li, Guicheng He, Hui Zeng, Zhen Wang, Hui Yang, Aitao Nai
PDF Pages: 3017-3034 Full Text (15) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Deep learning for fine-grained molecular-based colorectal cancer classification
Junyu Bian, Yansong Li, Yamei Dang, Yonglin Chen
PDF Pages: 3035-3046 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
The role of radiotherapy in distant nasopharyngeal carcinoma: a SEER analysis
Long Chen, Dun-Chang Mo, Jin-Nian He, Ke-Jiang Du, Li-Ping Peng, Shi-Hua Yin
PDF Pages: 3047-3056 Full Text (9) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Machine learning and deep learning to improve overall survival prediction in cervical cancer patients
Nan Jiang, Xing Xiong, Xue Chen, Mengmeng Feng, Yan Guo, Chunhong Hu
PDF Pages: 3057-3068 Full Text (13) Reporting Checklist Peer Review File COI Form Open Access Get Permission
The prognostic and immune significance of fibronectin type III domain-containing 1 gene in pan-cancer and its relationship with proliferation and migration of stomach adenocarcinoma
Minying Deng, Wen Huang, Rongkui Luo, Huimei Wang, Zixiang Yu, Benting Ma, Lei Xu, Xiaolei Zhang, Jieakesu Su, Chen Xu, Yingyong Hou
PDF Pages: 3069-3095 Full Text (6) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Developing a prognostic risk model based on circulating tumor cell genes to predict prognosis and provide potential therapeutic strategies in colorectal cancer
Yupeng Zheng, Mian Yang, Hongyi Yi, Tao Peng, Jiaze Sun, Jiazi Yu
PDF Pages: 3096-3112 Full Text (7) Reporting Checklist Peer Review File COI Form Open Access Get Permission
Identification and validation of hypoxia-associated genes positively correlated with HIF1A in pulmonary adenocarcinoma
Haifeng Zhu, Yun Wang, Zunyu Chen, Ruonan Guo, Xiaobai Wu, Yifan Jiang, Yang Shu, Hanpeng Huang
PDF Pages: 3113-3132 Full Text (11) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis
Ansu Li, Wu Sun, Shihe Shao, Xuefeng Qiu, Jianpeng Hu, Feilun Cui
PDF Pages: 3133-3148 Full Text (8) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Ubiquitin-specific peptidase 20 affects immune cell infiltration by regulating prostaglandin E2 on intraperitoneal metastasis model of colorectal cancer
Yang Hua, Xiukun Ma, Xinyu Zhao, Xiaomeng Wei, Xiaojing Mu, Botao Wang, Xiangfei Yuan
PDF Pages: 3149-3160 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
A real-world retrospective cohort study: the clinical outcomes and characteristics of platinum-resistant recurrent ovarian cancer
Qing Wang, Lei Kuang, Boyang Liu, Qi Chen, Yanyu Li, Jiayun Zhou, Jingbo Zhang, Xinhui Yang, Guiping Wan, Jörg Wischhusen, Rosa A. Salcedo-Hernández, Colton Ladbury, Zeyuan Yin, Bei Zhang
PDF Pages: 3161-3174 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma
Zhihao Li, Hui Xu, Hao Chen, Liang Chen, Hong Zang, Yi Qian
PDF Pages: 3175-3185 Full Text (12) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Plasma-derived exosomal human epidermal growth factor receptor 2 (HER2) protein for distinguishing breast cancer from benign breast disease and assessing the efficacy of neoadjuvant therapy
Xiaofang Yang, Mengdan Xu, Yu Xia, Zhaofen Ba, Chunmiao Han, Yipu Wang, Jinwen Qu, Yu Wang, Yehui Zhou, Rong Wang, Jing Lan
PDF Pages: 3186-3200 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Immunocytochemical staining for p16, Ki-67, and MCM2 in the detection of cervical lesions and cancer: a prospective observational study
Yunyue Liu, Liang Wen, Lingjie Jiang, Jia Xu, Yuanguang Meng, Wen Yang
PDF Pages: 3201-3211 Full Text (7) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Significant weight gain benefits of nanocrystalline megestrol acetate for patients with cancer anorexia-cachexia syndrome
Xue Cheng, Kang Pan, Qing Li, Xin Jin, Chengsong Cao, Yong Liu
PDF Pages: 3212-3225 Full Text (9) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission
Sphingosine kinase 1 facilitates gastric cancer progression via STAT1 gene methylation-mediated mechanisms
Yunfei Wang, Fei Wang, Bingxi Zhou, Jia Lu, Jiabei Xie, Lijie Yuan, Shuangyin Han
PDF Pages: 3226-3238 Full Text (17) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access Get Permission

Review Article

Ovarian cancer and malnutrition: a literature review
Zhuyan Shao, Liying Fu, Yi Lu, Haifei Zhou, Yuyang Zhu, Tao Zhu
PDF Pages: 3239-3254 Full Text (10) Reporting Checklist Peer Review File COI Form Open Access Get Permission

Case Report

Endobronchial malignancy as a manifestation of advanced ovarian cancer recurrence: a case report and literature review
Dongrui Zhang, Li Yang, Alexandros Laios, Wei Jia
PDF Pages: 3255-3262 Full Text (6) Reporting Checklist Peer Review File COI Form Open Access Get Permission

Erratum

Erratum: The prognostic significance of fragile X mental retardation syndrome-related protein 1 (FXR1) in breast cancer
Editorial Office
PDF Pages: 3263 Full Text (6) Open Access Get Permission
Erratum: Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway
Editorial Office
PDF Pages: 3264-3269 Full Text (7) Open Access Get Permission

Retraction

Retraction: TGF-β signaling proteins and CYP24A1 may serve as surrogate markers for progesterone calcitriol treatment in ovarian and endometrial cancers of different histological types
Editorial Office
PDF Pages: 3270 Full Text (18) Open Access Get Permission
Retraction: H19/miR-152-3p/TCF4 axis increases chemosensitivity of gastric cancer cells through suppression of epithelial-mesenchymal transition
Xiaodong Jiang, Wenbin Ding, Weiguang Shen, Jie Jin
PDF Pages: 3271 Full Text (18) COI Form Open Access Get Permission