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Interviews with Editorial Board Members

TCR features a distinguished editorial board, the members of which continue to instill the power of their expertise for the journal’s development. By launching this column, we are glad to introduce to you some of them in the form of interviews, in which they will share their unique career experiences and perspectives. We believe their insights will shed light on the knowledge of related fields.

Interviews with Guest Editors

Over the years, a number of TCR guest editors have made valuable contributions to the journal. This column features interviews with our guest editors, who graciously share their experience in scientific careers and provide insightful perspectives on the special series.

New Impact Factor for Translational Cancer Research: 1.5

We are pleased to announce that Translational Cancer Research (TCR) has attained its latest impact factor update for the 2023 citation year: 1.5.

Translational Cancer Research 2023 CiteScore Released: 2.1

We are pleased to announce that the Translational Cancer Research (TCR) has received its 2023 CiteScore: 2.1, ranking 209 out of 333 journals in the Radiology, Nuclear Medicine and Imaging category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

Interviews with Outstanding Authors (2024)

In 2024, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspectives and insightful views as authors.

Reviewer of the Month (2024)

In 2024, TCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

TCR 2023 Annual Report

Greetings from the Editorial Office of TCR!

We are pleased to share the 2023 Annual Report of Translational Cancer Research. 2023 has seen much progress for TCR. We hope 2023 will bring greater things to TCR. We would like to thank you for your support and assistance in improving the journal over the past year, and we certainly look forward to your innovations and contributions in 2024.

We would especially like to express our sincere gratitude to the editorial board members, guest editors, reviewers, authors, and readers for all your support and contributions to TCR. We wish you a happy, healthy and prosperous 2024!

Ferroptosis and cuproptosis prognostic signature for prediction of prognosis, immunotherapy and drug sensitivity in hepatocellular carcinoma: development and validation based on TCGA and ICGC databases

Identification of differentially expressed genes. (A) Heatmap revealed differentially expressed genes; (B) univariate Cox regression analysis; (C) a protein-protein interaction network showing the relationship between ferroptosis-related genes and cuproptosis-related genes.

Bartholin’s gland carcinoma—the diagnostic and management challenges of a rare malignancy—a case report and review of current literature

FDG-avid right inguinal lymph node on axial CT-PET. The green arrow: FDG-avid right inguinal lymph node on axial CT-PET. FDG, fluorodeoxyglucose; CT-PET, computed tomography-positron-emission tomography.

Development of a novel angiogenesis-related lncRNA signature to predict the prognosis and immunotherapy of glioblastoma multiforme

Differences in risk scores for clinical characteristics. (A-D) The correlations between the risk score and sex, age, MGMT status, and IDH1 status were not significant (P>0.05). (E) Among the subtypes, the proneural subtypes had a significantly lower risk score than did the mesenchymal subtypes (P<0.05). **, P<0.01. IDH1, isocitrate dehydrogenase 1; MGMT, O6-methylguanine-DNA methyltransferase; ns, no significance.

Integrated analysis of single-cell and bulk transcriptome identifies a signature based on NK cell marker genes to predict prognosis and therapeutic response in clear cell renal cell carcinoma

Single-cell sequencing analysis of 20,074 cells from 7 ccRCC samples. (A) Pearson’s correlation between nFeature and nCount. (B) PCA plot colored by different samples. (C) Cells were classified into 25 clusters via UMAP algorithm. (D) Eight cell types were identified and annotated by marker genes. (E) Heatmap visualized top 5 marker genes among 8 cell clusters. (F) Visualization of gene expression in cell clusters. PC, principal component; UMAP, uniform manifold approximation and projection; NK, nature killer; ccRCC, clear cell renal cell carcinoma; PCA, principal component analysis.

Development and validation of nomograms to predict early death in non-small cell lung cancer patients with brain metastasis: a retrospective study in the SEER database

ROC curves for the nomograms of the all-cause early death and the cancer-specific early death in the training cohort (A,B) as well as in the validation cohort (C,D). ROC, receiver operating characteristic; AUC, area under the curve.

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Vol 13, No 11 (November, 2024)

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Announcement more

19th Asian Society for Neuro-Oncology (ASNO) Annual Meeting

The 19th Asian Society for Neuro-Oncology (ASNO) Annual Meeting will be held at the One Farrer Hotel, Singapore from 16 – 18 August 2024. More >>

New Impact Factor for Translational Cancer Research: 1.5

We are pleased to announce that Translational Cancer Research (TCR) has attained its latest impact factor update for the 2023 citation year: 1.5. More >>

Translational Cancer Research 2023 CiteScore Released: 2.1

We are pleased to announce that the Translational Cancer Research (TCR) has received its 2023 CiteScore: 2.1, ranking 209 out of 333 journals in the Radiology, Nuclear Medicine and... More >>

Editorial

The usefulness of Hinotori^TM which is a surgical support robot system developed in Japan and a challenging case of robot-assisted surgery

Takuya Koie

PDF Pages: 5723-5724 Full Text (133) COI Form Open Access

Original Article

Elucidating the molecular and immune interplay between head and neck squamous cell carcinoma and diffuse large B-cell lymphoma through bioinformatics and machine learning

Jing Zheng, Xinxin Li, Xun Gong, Yuan Hu, Min Tang

PDF Pages: 5725-5750 Full Text (388) Reporting Checklist Peer Review File COI Form Open Access

Construction of ferroptosis and pyroptosis model to assess the prognosis of gastric cancer patients based on bioinformatics

Hanlu Shi, Hongfeng Yao, Yi Zhou, Gaoping Wu, Keyi Li, Lusheng Tang, Chen Yang, Dong Wang, Weidong Jin

PDF Pages: 5751-5770 Full Text (316) Reporting Checklist Peer Review File COI Form Open Access

Prognostic significance of B cell senescence-associated genes as risk markers in prostate adenocarcinoma

Huaiying Zheng, Wei Jiang, Shaoxing Zhu, Xiaobao Chen

PDF Pages: 5771-5783 Full Text (225) Reporting Checklist Peer Review File COI Form Open Access

Copper metabolism-related lncRNAs predict prognosis and immune landscape in liver cancer patients

Rui Luo, Shu Huang, Xiaomin Shi, Huan Xu, Jieyu Peng, Wenjie Lei, Shiqi Li, Wei Zhang, Lei Shi, Yan Peng, Xiaowei Tang

PDF Pages: 5784-5800 Full Text (188) Reporting Checklist Peer Review File COI Form Open Access

Immunogenic cell death-related signature predicts prognosis and immunotherapy efficacy in bladder cancer

Long Guo, Na Chen, Mei Qiu, Juliang Yang, Min Zhou, Fei Liu

PDF Pages: 5801-5814 Full Text (219) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Determining new disulfidptosis-associated lncRNA signatures pertinent to breast cancer prognosis and immunological microenvironment

Yifan Zheng, Yufeng Lin, Yongcheng Zhang, Shangjie Liu, Yongxia Yang, Wenbin Huang

PDF Pages: 5815-5829 Full Text (178) Reporting Checklist Peer Review File COI Form Open Access

Pan-cancer analysis combined with experimental validation revealed that KTN1 is an immunological and prognostic biomarker

Yan Ouyang, Yu Shen, Shengming Lai, Haiyan Huang, Yongsheng Huang, Shuwei Ren

PDF Pages: 5830-5844 Full Text (216) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Nomogram for predicting the early death of patients with stage IV ovarian cancer: a retrospective analysis of the SEER database

Pan Chen, Shunjie Zheng, Lin Zhang

PDF Pages: 5845-5855 Full Text (182) Reporting Checklist Peer Review File COI Form Open Access

Identification of the CD8⁺ T-cell exhaustion signature of hepatocellular carcinoma for the prediction of prognosis and immune microenvironment by integrated analysis of bulk- and single-cell RNA sequencing data

Jianhui Fan, Qinghua Zhang, Tiancong Huang, Haitao Li, Guoxu Fang

PDF Pages: 5856-5872 Full Text (209) Reporting Checklist Peer Review File COI Form Open Access

Development of a risk prediction model for personalized assessment of postoperative recurrence risk in colon cancer patients

Jing-Jing Zhang, Ya-Meng Liu, Ya-Wei Li, Zheng-Quan Han

PDF Pages: 5873-5882 Full Text (165) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic signature detects homologous recombination deficient in glioblastoma

Dongdong Luo, Aiping Luo, Su Hu, Hailin Zhao, Xuefeng Yao, Dan Li, Biao Peng

PDF Pages: 5883-5897 Full Text (185) Reporting Checklist Peer Review File COI Form Open Access

The relationship between marital status and survival in primary bone cancer: a population-based study

Xiaoxia Huang, Leilei Tian, Chuang Li, Jinling Liu, Rui Shi, Fang Lin, Yi Luo

PDF Pages: 5898-5908 Full Text (144) Reporting Checklist Peer Review File COI Form Open Access

Construction of a disulfidptosis-related lncRNAs signature of the subtype, prognostic, and immunotherapy in neuroblastoma

Yongcheng Fu, Nan Zhang, Jingyue Wang, Yuanyuan Wang, Da Zhang

PDF Pages: 5909-5928 Full Text (178) Reporting Checklist Peer Review File COI Form Open Access

Alpha-fetoprotein-to-PIVKA-II ratio as a potential biomarker for hepatocellular carcinoma differentiation, imaging characteristics, and patient survival

Menene Nkonika Dieu-Merci, Jihong Hu, Xinyi Fang, Renjie Zhao, Xiaojie Xie, Wenqiu Pan, Thapa Aayush, Fang Yin, Hu Xingyue, Dan Han

PDF Pages: 5929-5942 Full Text (136) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development of prediction models for liver metastasis in colorectal cancer based on machine learning: a population-level study

Yuncan Xing, Guanhua Yu, Zheng Jiang, Zheng Wang

PDF Pages: 5943-5952 Full Text (356) Reporting Checklist Peer Review File COI Form Open Access

Bioinformatics analysis reveals VEGFC’s prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration

Yulian Tang, Ting Hu, Wenli Yin, Changqiao Huang, Dewen Liu, Fengming Lai, Chengliang Yang, Lizhu Tang

PDF Pages: 5953-5970 Full Text (222) Reporting Checklist Peer Review File COI Form Open Access

Exploring potential causal genetic variants and genes for endometrial cancer: Open Targets Genetics, Mendelian randomization, and multi-tissue transcriptome-wide association analysis

Guorui Zhang, Su Mao, Guangwei Yuan, Yang Wang, Jingyun Yang, Yuxin Dai

PDF Pages: 5971-5982 Full Text (214) Reporting Checklist Peer Review File COI Form Open Access

Dephosphorylation-related signature predicts the prognosis of papillary renal cell carcinoma

Jia Feng, Longyang Jiang, Hui Tang, Yuankai Si, Li Luo, Jing Liu, Dengmin Hu, Yilan Huang

PDF Pages: 5983-5994 Full Text (155) Reporting Checklist Peer Review File COI Form Open Access

Prognostic analysis of SYTL4 in acute myeloid leukemia

Kun-Ying Xie, Jin Wei

PDF Pages: 5995-6003 Full Text (125) Reporting Checklist Peer Review File COI Form Open Access

The prognosis and treatment consideration for non-small cell lung carcinoma patients with tumor size of >2.0–3.0 cm and visceral pleural invasion: a SEER-based study

Xirui Lin, Haijie Xu, Jianrong Chen, Jiaying Wu, Jiong Lin, Hansheng Wu

PDF Pages: 6004-6017 Full Text (199) Reporting Checklist Peer Review File COI Form Open Access

Therapy-related myeloid neoplasms in Korean patients with ovarian or primary peritoneal cancer treated with poly(ADP-ribose) polymerase inhibitors

Yoon Jung Jang, Heyjin Kim, Sang-Young Ryu, Moon-Hong Kim, Beob-Jong Kim, Hee Jung Jung, Jisik Kang, Sung Hyun Yang, Im Il Na, Hyo-Rak Lee, Hye Jin Kang

PDF Pages: 6018-6027 Full Text (153) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Multi-omics decipher the immune microenvironment and unveil therapeutic strategies for postoperative ovarian cancer patients

Zhibing Liu, Fei Wang, Weiwei Chen, Yujie Zhai, Jinbo Jian, Xiaole Wang, Yingjiang Xu, Jiajia An, Lei Han

PDF Pages: 6028-6044 Full Text (161) Reporting Checklist Peer Review File COI Form Open Access

Comparison of postoperative radiotherapy and definitive radiotherapy for non-metastatic adenoid cystic carcinoma of the head and neck, a propensity score matching based on the SEER database

Mingyu Tan, Yanliang Chen, Tianqi Du, Qian Wang, Xun Wu, Xiaohu Wang, Hongtao Luo, Shilong Sun, Qiuning Zhang, Wenzhen Yuan

PDF Pages: 6045-6056 Full Text (175) Reporting Checklist Peer Review File COI Form Open Access

SKA1/2/3 link to poor prognosis and immune infiltration of head and neck squamous cell carcinomas

Churen Zhang, Jianguo Ke, Jia Li, Qiaoling Cai

PDF Pages: 6057-6069 Full Text (123) Reporting Checklist Peer Review File COI Form Open Access

Potential role of TWIST1 and its methylation in bladder urothelial carcinoma

Meixuan Wan, Hongxue Meng, Huining Li

PDF Pages: 6070-6086 Full Text (160) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Neuroepithelial cell transforming 1 as a key regulator in non-small cell lung cancer: unveiling causal links and therapeutic potentials

Xiaoqing Shangguan, Xinping Zhang, Xiwu Chen, Zheng Zhang, Lei Wang

PDF Pages: 6087-6104 Full Text (192) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Emerging functions of FMNL1 in myeloid neoplasms: insights from bioinformatics to biological and pharmacological landscapes

João Agostinho Machado-Neto, Hugo Passos Vicari, Jean Carlos Lipreri da Silva, Maria Fernanda Lopes Carvalho, Keli Lima

PDF Pages: 6105-6116 Full Text (202) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Construction and validation of a novel prognostic model with palmitoylation-related genes for glioblastoma

Guowen Qin, Gang Pang, Shuaishuai Wu, Shuiqing Bi, Shengyong Lan, Xiuwen Tang, Beiquan Hu, Junlin Zhou, Fengning Shi, Chengjian Qin

PDF Pages: 6117-6135 Full Text (159) Reporting Checklist Peer Review File COI Form Open Access

A novel immune-related gene prognostic signature combining immune cell infiltration and immune checkpoint for glioblastoma patients

Xu Liu, Xiaomei Liu

PDF Pages: 6136-6153 Full Text (118) Reporting Checklist Peer Review File COI Form Open Access

Epidemiological characteristics of myxopapillary ependymoma and factors affecting overall survival: a SEER-based analysis

Ge Huang, Zhengyuan Xie, Jinhong Li

PDF Pages: 6154-6164 Full Text (127) Reporting Checklist Peer Review File COI Form Open Access

A lncRNA signature associated with endoplasmic reticulum stress supports prognostication and prediction of drug resistance in acute myelogenous leukemia

Yu Fu, Shupeng Wang, Lingyu Meng, Yahui Liu

PDF Pages: 6165-6181 Full Text (133) Reporting Checklist Peer Review File COI Form Open Access

Integrative multi-omics and machine learning approach reveals tumor microenvironment-associated prognostic biomarkers in ovarian cancer

Wenzhi Jiao, Shasha Yang, Yue Li, Yu Li, Shanshan Liu, Jianwei Shi, Minmin Yu

PDF Pages: 6182-6200 Full Text (158) Reporting Checklist Peer Review File COI Form Open Access

ABALON regulates mitophagy and 5-FU sensitivity in colorectal cancer via PINK1-Parkin pathway

Huimin Liu, Ying Huang, Chunmei Zhao, Guihua Wang, Xudong Wang

PDF Pages: 6201-6218 Full Text (186) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The expression and prognostic value of IFIT3 in esophageal squamous cell carcinoma

Jiawang Cao, Qipeng Zhang, Yiwen Xuan, Zhuan Ou, Qinghua Yu, Daoqi Zhu, Enwu Xu

PDF Pages: 6219-6234 Full Text (105) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Landscape and prognostic significance of oncogene drivers in metastatic castration sensitive prostate cancer

Theodore Wang, Jongmyung Kim, Ritesh Kumar, Rebecca A. Deek, Ryan Stephenson, Tina Mayer, Biren Saraiya, Saum Ghodoussipour, Thomas Jang, David Golombos, Vignesh Packiam, Ronald Ennis, Lara Hathout, Salma K Jabbour, Ozan Guler, Cem Onal, Matthew P. Deek

PDF Pages: 6235-6245 Full Text (122) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Integrating artificial intelligence in renal cell carcinoma: evaluating ChatGPT’s performance in educating patients and trainees

J. Patrick Mershon, Tasha Posid, Keyan Salari, Richard S. Matulewicz, Eric A. Singer, Shawn Dason

PDF Pages: 6246-6254 Full Text (138) Data Sharing Statement Peer Review File COI Form Open Access

FLT3 mutation-related immune checkpoint molecule absent in melanoma 2 (AIM2) contributes to immune infiltration in pediatric and adult acute myeloid leukemia: evidence from bioinformatics analysis

Jing Zhao, Yue Cui, Hua Zhou, Dongming Zhou, Zhiping Che, Ning Zhang, Qi Yun, João Agostinho Machado-Neto, Daniela Damiani, Lika’a Fasih Y. Al-Kzayer, Rohan Kulkarni, Meng Gu

PDF Pages: 6255-6272 Full Text (243) Reporting Checklist Peer Review File COI Form Open Access

PARP1 promotes tumor proliferation in lenalidomide-resistant multiple myeloma via the downregulation of microRNA-192-5p-AKT signaling

Yuqing Luo, Yalu Chen, Cheng Ai, Xiaguang Huang, Fabiana Perna, Brandon J. Kale, Say Min Lim, Meier Gu, Panpan Gao, Chunmeng Rong, Zefeng Zhou, Yiqin Weng, Yinyan Jiang, Fang Yang, Yongming Xia

PDF Pages: 6273-6281 Full Text (167) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Novel cuprotosis-related gene signature: a prognostic indicator and regulator of the glioma immune microenvironment

Dongming Gao, Lin Zhou, Youyuan Bao, Wenyin Shi, Lei Li, Liang Gao

PDF Pages: 6282-6297 Full Text (180) Reporting Checklist Peer Review File COI Form Open Access

Increased expression of HBXIP (LAMTOR5) predicts poor prognosis and is correlated with immune-cell infiltration in glioma

Linyang Shi, Hui Chen, Junmin Chen, Joshua D. Palmer, Lin Wang, Li Sheng

PDF Pages: 6298-6314 Full Text (176) Reporting Checklist Peer Review File COI Form Open Access

SLC1A3 knockdown in inhibiting the proliferation, apoptosis resistance, and migration of ovarian cancer cells

Wu Zhou, Yanqiang Xiong, Liangping Zhao, Gabriel Levin, Felipe Batalini, Zhihui Liu, Yuanxue Ma

PDF Pages: 6315-6322 Full Text (178) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Postexercise downregulation of NUP155 in regulating non-small cell lung cancer progression via the PTEN/AKT signaling pathway

Jiangang Xu, Liyin Zhang, Menghui Feng, Weijun Hong, Xinming Ye

PDF Pages: 6323-6335 Full Text (153) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The efficacy of plasma exosomal miRNAs as predictive biomarkers for PD-1 blockade plus chemotherapy in gastric cancer

Yunqi Hua, Shuang Luo, Qian Li, Ge Song, Xiaoling Tian, Peng Wang, Hongwei Zhu, Shuang Lv, Xinyi Zhang, Zixuan Yang, Geoffrey Ku, Guo Shao

PDF Pages: 6336-6346 Full Text (212) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

CTNND2 gene expression in melanoma tissues and its effects on the malignant biological functions of melanoma cells

Jiaojiao Qu, Xianfeng Cheng, Mingyan Liu, Qiang Zhang

PDF Pages: 6347-6363 Full Text (178) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

N-acetyltransferase 10 as a novel prognostic biomarker in papillary renal cell carcinoma: a machine learning and experimental validation study

Liyang Li, Fan Li, Chenghao Zhou, Kangxin Ni, Haiyi Hu, Mingchao Wang, Huan Wang, Lei Gao

PDF Pages: 6364-6380 Full Text (193) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

GCNT3 promotes the proliferation, apoptosis, invasion, and migration of breast cancer through the PI3K/AKT pathway

Yifan Li, Zhen Ren, Teng Wu, Nannan Zhang, Zhixian He

PDF Pages: 6381-6393 Full Text (154) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Brief Report

Sex-based differences in CEACAM5 expression in lung cancer

Gavitt A. Woodard, Emma R. Kane, Nicholas Todorovic, Samantha Prince, Sanja Dacic, Lieping Chen

PDF Pages: 6394-6402 Full Text (189) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Non-clear cell renal cell carcinoma narrative review: where we are in 2024

Michael J. Pierro, Alexander Gallan, Deepak Kilari

PDF Pages: 6403-6412 Full Text (124) Reporting Checklist Peer Review File COI Form Open Access

Bladder sparing management for muscle-invasive bladder cancer after a complete clinical response: ready for prime time?—a narrative review

Mann Patel, Kyle Moore, Benjamin L. Lichtbroun, Ryan D. Stephenson, Tina Mayer, Biren Saraiya, David Golombos, Thomas Jang, Vignesh T. Packiam, Saum Ghodoussipour

PDF Pages: 6413-6429 Full Text (137) Reporting Checklist Peer Review File COI Form Open Access

Winning hearts & minds: prostate cancer outreach and clinical trial enrollment in minority men

Rebecca Anderson, Aleksander Popovic, Matthew Davis, Evan Kovac

PDF Pages: 6430-6437 Full Text (123) Peer Review File COI Form Open Access

Management of translocation carcinomas of the kidney

Yasser Ged, Ardit Feinaj, Ezra Baraban, Nirmish Singla

PDF Pages: 6438-6447 Full Text (155) Peer Review File COI Form Open Access

Adjuvant therapy in renal cell carcinoma (RCC): progress, at last

Andrew N. Bueno, Mark N. Stein, Karie Runcie

PDF Pages: 6448-6462 Full Text (135) Peer Review File COI Form Open Access

Contemporary surgical management of testicular seminoma

Rachel Passarelli, John L. Pfail, Thomas L. Jang

PDF Pages: 6463-6472 Full Text (87) Peer Review File COI Form Open Access

Management strategies for radio-recurrent prostate cancer: a comprehensive review

Syed N. Rahman, Hyung Suk Kim, Lindsey T. Webb, Gabriela M. Diaz, Michael S. Leapman, Preston C. Sprenkle, Joseph M. Brito, Joseph Renzulli, Thomas V. Martin, Patrick Kenney, Isaac Yi Kim

PDF Pages: 6473-6488 Full Text (122) Peer Review File COI Form Open Access

Predicting response to bacillus Calmette-Guerin in high-risk non-muscle invasive bladder cancer

Amir M. Soltani-Tehrani, Aman Kumar, Kamal S. Pohar

PDF Pages: 6489-6502 Full Text (88) Peer Review File COI Form Open Access

Treatment approaches for prostate cancer in sub-Saharan Africa

Brooke Kania, Kirthana Sharma, Pleasure Ramatlho, Peter Vuylsteke, Andrew Ndlovu, Tina Mayer

PDF Pages: 6503-6510 Full Text (115) Peer Review File COI Form Open Access

Perioperative systemic therapy in high-risk renal cell carcinoma following nephrectomy: a narrative review

Adam Khorasanchi, Taylor Goodstein, Shawn Dason, Eric A. Singer, Danielle Zimmerman, Yuanquan Yang

PDF Pages: 6511-6528 Full Text (148) Reporting Checklist Peer Review File COI Form Open Access

A narrative clinical trials review in the realm of focal therapy for localized prostate cancer

Alon Lazarovich, Vijay Viswanath, Aaron S. Dahmen, Abhinav Sidana

PDF Pages: 6529-6539 Full Text (98) Reporting Checklist Peer Review File COI Form Open Access

Targeting C797S mutations and beyond in non-small cell lung cancer—a mini-review

Wolfram C. M. Dempke, Klaus Fenchel

PDF Pages: 6540-6549 Full Text (198) Peer Review File COI Form Open Access

Targeting breast cancer resistance protein (BCRP/ABCG2) in cancer

Rouan Chen, Yue Yu, Ruixin Liu, Qian Chen

PDF Pages: 6550-6564 Full Text (107) Peer Review File COI Form Open Access

Immunotherapy for locally advanced and metastatic basal cell carcinoma: a narrative review

Xiaoqing Li, Hongru Wang, Qingli Lu

PDF Pages: 6565-6575 Full Text (133) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Malignant phyllodes tumor of the breast with bilateral ductal carcinoma in situ and postoperative distant metastasis: a case report

Hongyu Liu, Bin Wang, Yuxingzi Chen

PDF Pages: 6576-6583 Full Text (133) Reporting Checklist Peer Review File COI Form Open Access

Massive gastrointestinal hemorrhage and iodine-125 seed migration due to hepatogastric fistula: a case report and literature review

Chengjian He, Jing Zhou, Naijian Ge, Xiaofeng Zhang, Xiangdong Wang, Yefa Yang

PDF Pages: 6584-6589 Full Text (138) Reporting Checklist Peer Review File COI Form Open Access

Editorial Commentary

Identifying biomarkers to predict immune-checkpoint therapy response—is it a reality or a distant dream?

Prashanth Ashok Kumar

PDF Pages: 6590-6593 Full Text (112) Peer Review File COI Form Open Access

The next frontier in breast cancer: genomic co-alteration and its impact on biology and treatment planning

Meredith Li, Eitan Amir

PDF Pages: 6594-6597 Full Text (89) Peer Review File COI Form Open Access

Retraction

Retraction: Matrine reverses the drug resistance of K562/ADM cells to ADM and VCR via promoting autophagy

Zhao Li, Ning Wang, Ting Yue, Lu Liu

PDF Pages: 6598 Full Text (139) COI Form Open Access

Review Article

The management of brain necrosis as a result of SRS treatment for intra-cranial tumors

Uresh Patel, Ankush Patel, Charles Cobb, Tara Benkers, Sandra Vermeulen

Published online: 28 August 2014

PDF Pages: 373-382 Full Text (126366) COI Form Open Access

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis

Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Published online: 05 March 2013

PDF Pages: 25-32 Full Text (76840) COI Form Open Access

Review Article

Common applications of next-generation sequencing technologies in genomic research

Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Published online: 05 March 2013

PDF Pages: 33-45 Full Text (66764) COI Form Open Access

Biological basis of IORT

Immune effects of high dose radiation treatment: implications of ionizing radiation on the development of bystander and abscopal effects

Ithaisa Sologuren, Carlos Rodríguez-Gallego, Pedro Carlos Lara

Published online: 25 February 2014

PDF Pages: 18-31 Full Text (47933) COI Form Open Access

Review Articles

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer

Rositsa Dueva, George Iliakis

Published online: 19 June 2013

PDF Pages: 163-177 Full Text (46335) COI Form Open Access

Review Articles

Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer

Deep Kwatra, Anand Venugopal, Shrikant Anant

Published online: 26 September 2013

PDF Pages: 330-342 Full Text (45769) COI Form Open Access

Editorial

Morphine, when used for treating patients with acute pancreatitis, could be more risky than previously suspected

Juan Iovanna, Maria Cecilia Mallmann

Published online: 24 October 2017

PDF Pages: S1166-S1168 Full Text (44059) COI Form Open Access

Original Article

Effect of fasting therapy in chemotherapy-protection and tumorsuppression: a systematic review

Lei Sun, Yong-Jiang Li, Xi Yang, Ling Gao, Cheng Yi

Published online: 28 April 2017

PDF Pages: 354-365 Full Text (43849) COI Form Open Access

Review Article

EGFR first- and second-generation TKIs—there is still place for them in EGFR-mutant NSCLC patients

Niki Karachaliou, Manuel Fernandez-Bruno, Jillian Wilhelmina Paulina Bracht, Rafael Rosell

Published online: 19 January 2019

PDF Pages: S23-S47 Full Text (38011) COI Form Open Access

Review Articles

Tumor microenvironment and nanotherapeutics

Meenakshi Upreti, Amar Jyoti, Pallavi Sethi

Published online: 26 September 2013

PDF Pages: 309-319 Full Text (37111) COI Form Open Access

Review Article

Cancer biomarker discovery and validation

Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida

Published online: 18 June 2015

PDF Pages: 256-269 Full Text (35917) COI Form Open Access

Biological basis of IORT

Cell and molecular response to IORT treatment

Luigi Minafra, Valentina Bravatà

Published online: 25 February 2014

PDF Pages: 32-47 Full Text (35501) COI Form Open Access

Editorial

The CROSS road in neoadjuvant therapy for esophageal cancer: long-term results of CROSS trial

Ian Wong, Simon Law

Published online: 29 September 2016

PDF Pages: S415-S419 Full Text (30778) COI Form Open Access

Review Articles

DNA damage tolerance: a double-edged sword guarding the genome

Gargi Ghosal, Junjie Chen

Published online: 19 June 2013

PDF Pages: 107-129 Full Text (28630) COI Form Open Access

Review Article

Multiple keratoacanthoma centrifugum marginatum—a case report and systematic review

Yiman Wang, Wenling Zhao, Yueping Zeng, Li Li, Hongzhong Jin

Published online: 30 December 2018

PDF Pages: 1743-1747 Full Text (28590) COI Form Open Access

Review Articles

DNA crosslinking damage and cancer - a tale of friend and foe

Yaling Huang, Lei Li

Published online: 19 June 2013

PDF Pages: 144-154 Full Text (28575) COI Form Open Access

Review Article

Do alkaline phosphatases have great potential in the diagnosis, prognosis, and treatment of tumors?

Tingting Jiang, Qun Zeng, Jun He

Published online: 20 October 2023

PDF Pages: 2932-2945 Full Text (28156) Peer Review File COI Form Open Access

Original Article

Intraoperative radiotherapy in locally-advanced and recurrent rectal cancer: retrospective review of 68 cases

Sergey Potemin, Ivan Uvarov, Igor Vasilenko

Published online: 26 April 2015

PDF Pages: 189-195 Full Text (27778) COI Form Open Access

Review Article

EGFR and HER2: is there a role in ovarian cancer?

Eleonora Teplinsky, Franco Muggia

Published online: 13 February 2015

PDF Pages: 107-117 Full Text (27414) COI Form Open Access

Review Article on Endometrial Cancer

Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer

Milan Milosav Terzic, Gulzhanat Aimagambetova, Sanja Terzic, Melanie Norton, Gauri Bapayeva, Simone Garzon

Published online: 23 December 2020

PDF Pages: 7716-7724 Full Text (27212) COI Form Open Access

Full Most Read article list >>

Original Article

A recursively partitioned mixture model for clustering time-course gene expression data

Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman

Statistical strategies for microRNAseq batch effect reduction

Yan Guo, Shilin Zhao, Pei-Fang Su, Chung-I Li, Fei Ye, Charles R. Flynn, Yu Shyr

Defining functional changes in the brain caused by targeted stereotaxic radiosurgery

Vipan K. Parihar, Munjal M. Acharya, Dante E. Roa, Omar Bosch, Lori-Ann Christie, Charles L. Limoli

A chain reaction approach to modelling gene pathways

Gary C. Cheng, Dung-Tsa Chen, James J. Chen, Seng-jaw Soong, Coral Lamartiniere, Stephen Barnes

Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA

Takashi Kon, Xiuwu Zhang, Qian Huang, Zhonghui Yang, Shanling Liu, Bin Yan, Fang Li, He Wang, Chuan-Yuan Li

Identification of cancer mechanisms through computational systems modeling

Zhen Qi, Eberhard O. Voit

Frameless single-isocenter intensity modulated stereotactic radiosurgery for simultaneous treatment of multiple intracranial metastases

Steven K. M. Lau, Xiao Zhao, Ruben Carmona, Erik Knipprath, Daniel R. Simpson, Sameer K. Nath, Gwe-Ya Kim, Jona A. Hattangadi, Clark C. Chen, Kevin T. Murphy

Matrix metalloproteinase (MMP) and immunosuppressive biomarker profiles of seven head and neck squamous cell carcinoma (HNSCC) cell lines

Amber M. Bates, Maria Paula Gomez Hernandez, Emily A. Lanzel, Fang Qian, Kim A. Brogden

Coexpression and expression quantitative trait loci analyses of the angiogenesis gene-gene interaction network in prostate cancer

Hui-Yi Lin, Chia-Ho Cheng, Dung-Tsa Chen, Y. Ann Chen, Jong Y. Park

How are lung cancer risk perceptions and cigarette smoking related?—testing an accuracy hypothesis

Lei-Shih Chen, Kimberly A. Kaphingst, Tung-Sung Tseng, Shixi Zhao

Alcohol intake patterns for cancer and non-cancer individuals: a population study

Hui-Yi Lin, Paige Fisher, Darian Harris, Tung-Sung Tseng

Application of Bayesian predictive probability for interim futility analysis in single-arm phase II trial

Dung-Tsa Chen, Michael J. Schell, William J. Fulp, Fredrik Pettersson, Sungjune Kim, Jhanelle E. Gray, Eric B. Haura

Review Article

Integrative clustering methods for high-dimensional molecular data

Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley

Sparse principal component analysis in cancer research

Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen

An improved understanding of cancer genomics through massively parallel sequencing

Jamie K. Teer

Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications

Louis Dubeau

Cancer biomarker discovery and validation

Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida

The promise and challenge of ovarian cancer models

Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Prostate cancer: unmet clinical needs and RAD9 as a candidate biomarker for patient management

Howard B. Lieberman, Alex J. Rai, Richard A. Friedman, Kevin M. Hopkins, Constantinos G. Broustas

Exosomal lncRNAs as new players in cell-to-cell communication

Mihnea Dragomir, Baoqing Chen, George A. Calin

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy

Souparno Bhattacharya, Aroumougame Asaithamby

Translational research in radiation-induced DNA damage signaling and repair

Jac A. Nickoloff, Mary-Keara Boss, Christopher P. Allen, Susan M. LaRue

Genetically engineered mouse models for studying radiation biology

Katherine D. Castle, Mark Chen, Amy J. Wisdom, David G. Kirsch

Renal cell carcinoma: the search for a reliable biomarker

Nicholas J. Farber, Christopher J. Kim, Parth K. Modi, Jane D. Hon, Evita T. Sadimin, Eric A. Singer

Advances on immunotherapy in genitourinary and renal cell carcinoma

Gregory P. Botta, Eric Granowicz, Carrie Costantini

The role of novel immunotherapies in non-Hodgkin lymphoma

Allyson Pishko, Sunita D. Nasta

MDMX under stress: the MDMX-MDM2 complex as stress signals hub

Anna de Polo, Varunika Vivekanandan, John B. Little, Zhi-Min Yuan

Do p53 stress responses impact organismal aging?

Paul Hasty, Judith Campisi, Z. Dave Sharp

Pharmacological targeting of mutant p53

Samuel Kogan, Darren Carpizo

Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis

Michael I. Carr, Stephen N. Jones

Regulation of cytotoxic T-cell responses by p53 in cancer

Mitchell W. Braun, Tomoo Iwakuma

The IGF-1R/AKT pathway determines cell fate in response to p53

Lei Duan, Carl G. Maki

Intra molecular interactions in the regulation of p53 pathway

Jiandong Chen

TP53 mutations in epithelial ovarian cancer

Yu Zhang, Lan Cao, Daniel Nguyen, Hua Lu

Modulation of the p53 family network by RNA-binding proteins

Chris Lucchesi, Jin Zhang, Xinbin Chen

Radiomics in head and neck cancer: from exploration to application

Andrew J. Wong, Aasheesh Kanwar, Abdallah S. Mohamed, Clifton D. Fuller

Prostate cancer radiomics and the promise of radiogenomics

Radka Stoyanova, Mandeep Takhar, Yohann Tschudi, John C. Ford, Gabriel Solórzano, Nicholas Erho, Yoganand Balagurunathan, Sanoj Punnen, Elai Davicioni, Robert J. Gillies, Alan Pollack

Positron emission tomography/computerized tomography for tumor response assessment—a review of clinical practices and radiomics studies

Wei Lu, Wengen Chen

The emerging field of radiomics in esophageal cancer: current evidence and future potential

Peter SN. van Rossum, Cai Xu, David V. Fried, Lucas Goense, Laurence E. Court, Steven H. Lin

Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat’s in the fire

Jung H. Suh, Julie D. Saba

Computational methods and opportunities for phosphorylation network medicine

Yian Ann Chen, Steven A. Eschrich

Editorial

Focusing in on radiation induced brain injury

M. Kerry O’Banion

Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic

Naomi Lomeli, Daniela A. Bota

Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma

David C. Binder, Erik Ladomersky, Alicia Lenzen, Lijie Zhai, Kristen L. Lauing, Sebastian D. Otto-Meyer, Rimas V. Lukas, Derek A. Wainwright

New light on the pancreatic cyst conundrum

Nathan A. Berger

HNF1A, KRT81, and CYP3A5: three more straws on the back of pancreatic cancer?

Andrew J. Scott, John C. Wilkinson

Bevacizumab as an adjuvant therapy for glioblastoma in elderly patients: the facts

Kristopher A. Lyon, Jason H. Huang

Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4

Nan Ding, Qianzheng Zhu

Hypofractionated whole breast irradiation is cost-effective—but is that enough to change practice?

Apar Gupta, Nisha Ohri, Bruce G. Haffty

Cost-effectiveness in managing skeletal related events in breast cancer: a strategy of less-intense dosing schedule of bone modifying agents

Sri Harsha Tella, Anuhya Kommalapati, Ryan K. Singhi

CRISPR-based genetic interaction maps inform therapeutic strategies in cancer

Poornima Ramkumar, Martin Kampmann

Smooth sailing for immunotherapy for unresectable stage III nonsmall cell lung cancer: the PACIFIC study

Melin J. Khandekar, Rakesh Jain

The evolving role of molecular profiling in prostate cancer: basal and luminal subtyping transcends tissue of origin

Omar Y. Mian, Rahul D. Tendulkar, Mohamed E. Abazeed

Serrated polyposis: the problem of definition and its relationship to the population at risk for syndrome-related colorectal cancer

Joanne P. Young, Timothy J. Price, Susan Parry

Multifactorial regulators of tumor programmed death-ligand 1 (PD-L1) response

R. Dixon Dorand, Agne Petrosiute, Alex Y. Huang

Therapeutic targeting of oncogenic KRAS in pancreatic cancer by engineered exosomes

Theresa L. Whiteside

TIC10/ONC201—a potential therapeutic in glioblastoma

Georg Karpel-Massler, Markus D. Siegelin

IDH mutational status and the immune system in gliomas: a tale of two tumors?

Bryan D. Choi, William T. Curry

ONC201: a new treatment option being tested clinically for recurrent glioblastoma

Marie D. Ralff, Amriti R. Lulla, Jessica Wagner, Wafik S. El-Deiry

When better still might not be good enough

Waldemar Debinski

Androgen receptor antagonism and impact on inhibitors of androgen synthesis in prostate cancer therapy

Vincent C. O. Njar

Co-inhibitory receptor programmed cell death protein 1 targets co-stimulatory CD28

Leonardo Chicaybam, Prasad S. Adusumilli

Exosome mediated phenotypic changes in lung cancer pathophysiology

Yoshihisa Shimada, John D. Minna

Signatures of field cancerization: a step towards earlier detection of esophageal adenocarcinoma

Aaron D. DeWard, Rebecca J. Critchley-Thorne

From tumorigenesis to microenvironment and immunoregulation: the many faces of focal adhesion kinase and challenges associated with targeting this elusive protein

Felicia L. Lenzo, William G. Cance

New incriminating evidence against IGF2

Wen Ding, Lina A. Shehadeh

Targeting cancer with tumor-specific therapeutic strategies—metabolic reprogramming beyond the Warburg effect

Paul Grippo, Ajay V. Maker

Branched chain amino acid metabolism and cancer: the importance of keeping things in context

Elizabeth M. Selwan, Aimee L. Edinger

RIPK1-TRAF2 interplay on the TNF/NF-κB signaling, cell death, and cancer development in the liver

Satomi Yamamoto, Tomoo Iwakuma

Genome-based modeling for adjusting radiotherapy dose (GARD)-a significant step toward the future of personalized radiation therapy

Michael J. Baine, Chi Lin

Rogue one: another faction of the Wnt empire implicated in assisting GBM progression

Riasat Ahsan, Shivani Baisiwala, Atique U. Ahmed

Normalizing tumoral vessels to treat cancer: an out-of-the-box strategy involving TIE2 pathway

Juan Fueyo, Mohammad B. Hossain, Teresa Nguyen, Candelaria Gomez-Manzano

Exploring gold nanoparticle interactions with proteins and the tumor microenvironment in biological systems

Li Tian, Ashley Chang, Marites P. Melancon

IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm

James P. White

Low-frequency ultrasound may improve drug penetration in colonic mucosa

Qiubing Chen, Bo Xiao, Didier Merlin

Dividing and conquering the variation among variants in EML4-ALK lung cancer

Trever G. Bivona

Unlocking the epigenetic code of T cell exhaustion

Jiazhu Wu, Huidong Shi

KDM1 links nuclear GSK3β to epigenetic alterations

Weijie Guo, Binhua P. Zhou

Moving the mountain in advanced non-small-cell lung cancer: evolving immunotherapies for a dire disease

Deepa Rangachari, Daniel B. Costa

Taming immune suppressor: application of myeloid-derived suppressor cells in anti-cancer gene therapy

Bhagelu R. Achyut, Ali S. Arbab

Neuroendocrine differentiation in prostate cancer: key epigenetic players

Karishma Gupta, Sanjay Gupta

PD-L1 is a diverse molecule regulating both tumor-intrinsic signaling and adaptive immunosuppression

Kim A. Brogden, Shireen Vali, Taher Abbasi

Mesenchymal stromal cells and interferon α (IFNα) in cancer immunotherapy

Diana Saleiro, Sara G. Radecki, Leonidas C. Platanias

The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Keith T. Schmidt, William D. Figg

Information-dense analysis for information-dense understanding

Nikola A. Ivica, Mandeep Kaur, Guangan Hu, Jianzhu Chen

The “liquid biopsy” in non-small cell lung cancer—not quite ready for prime time use

Angel Qin, Nithya Ramnath

Immune infiltration, glioma stratification, and therapeutic implications

Manny D. Bacolod, Sarmistha Talukdar, Luni Emdad, Swadesh K. Das, Devanand Sarkar, Xiang-Yang Wang, Francis Barany, Paul B. Fisher

Balancing redox stress: anchorage-independent growth requires reductive carboxylation

Clint.A Stalnecker, Ahmad.A Cluntun, Richard.A Cerione

Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy

Fabiana Perna, Michel Sadelain

Harnessing protein kinase A activation to induce mesenchymal-epithelial programs to eliminate chemoresistant, tumor-initiating breast cancer cells

Alex J. Gooding, William P. Schiemann

Actionable intelligence provided by pancreatic cancer genomic landscape: are targets for curative therapy on the map?

Nathan A. Berger

Microtubule targeting agents in glioma

Anda-Alexandra Calinescu, Maria G. Castro

Moving molecular subtypes to the clinic in gastric cancer

Joseph Chao, Jeeyun Lee, Samuel J. Klempner

Intraoperative subtyping of lung adenocarcinoma: an unmet need

Nurlan Aliyev, Yusuke Takahashi, Shaohua Lu, Marissa Mayor, Prasad S. Adusumilli

Emerging roles of FGF signaling in hepatocellular carcinoma

Nana Zheng, Wenyi Wei, Zhiwei Wang

Tregs, Helios and tumor immunity: the sun has not yet risen

Angela M. Thornton, Ethan M. Shevach

Immune checkpoint regulator: a new assignment proposed for the classic adhesion molecule P-selectin glycoprotein ligand-1

Jiaxuan Chen, Carolyn A. Haller, Elliot L. Chaikof

Sarcomatoid renal cell carcinoma: genomic insights from sequencing of matched sarcomatous and carcinomatous components

Brandon J. Manley, James J. Hsieh

Multimodal action of ONECUT2 in driving neuroendocrine prostate cancer

Salma Kaochar, Nicholas Mitsiades

Letter to the Editor

Epigenetic regulation of PD-L1 expression and pancreatic cancer response to checkpoint immunotherapy

Chunwan Lu, Kebin Liu

Synthetic lethality vs. synthetic viability due to PARP1 and BRCA2 loss

Xia Ding, Shyam K. Sharan

Correspondence

Targeted attack: mechanisms by which ovarian cancers suppress the immune system

Irina V. Tiper, Tonya J. Webb

Brief Report

The impact of neighborhood disadvantage on health-related quality of life among African American and white cancer survivors

Chien-Ching Li, Alicia K. Matthews, Anjali Asthana, Raj C. Shah

Research Highlight

Butyrate consumption of differentiated colonocytes in the upper crypt promotes homeostatic proliferation of stem and progenitor cells near the crypt base

Scott J. Bultman

Commentary

Molecular heterogeneity of localized prostate cancer: more different than alike

Jeffrey J. Tosoian, Emmanuel S. Antonarakis

A crowded, but still varied, space: brigatinib in anaplastic lymphoma kinase-rearranged non-small cell lung cancer

Sawsan Rashdan, David E. Gerber

MOAP-1, UBR5 and cisplatin resistance in ovarian cancer

Scott T. Eblen, Amber Bradley

Exportin 1/chromosome region maintenance 1 as a therapeutic target for lung cancer

Weimin Gao

The role of tumor-derived exosomes in epithelial mesenchymal transition (EMT)

Theresa L. Whiteside

[¹⁸F]-choline PET/CT as an imaging biomarker for primary liver cancers

Zhenghong Lee

Empiric H. pylori therapy—10-day concomitant, bismuth quadruple or 14-day triple therapy: none is best

Yoshio Yamaoka, David Y. Graham

JAK3-mediated phosphorylation of EZH2: a novel mechanism of non-canonical EZH2 activation and oncogenic function

Theodoros Karantanos, Vassiliki A. Boussiotis

Cisplatin, etoposide, and irinotecan for relapsed small-cell lung cancer

Angel Qin, Gregory P. Kalemkerian

Helicobacter pylori vacuolating cytotoxin and gastric cancer risk: reconsidered

Muhammad Miftahussurur, Yoshio Yamaoka, David Y. Graham

Colonic crypts are natural gatekeepers of microbial metabolites to protect stem cells

Praveen Kumar Vemula, Venkatakrishna Rao Jala

Helios—controller of Treg stability and function

Claire Chougnet, David Hildeman

Directing abiraterone metabolism: balancing the scales between clinical relevance and experimental observation

Jon K. Obst, Marianne D. Sadar

Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase

Pawel K. Mazur, Or Gozani, Julien Sage, Nicolas Reynoird

Fat lure: adipocytes attract cancer cells out of the prostate

Alexandra M. Blee, Haojie Huang

Impact of genomic heterogeneity associated with acquired anti-EGFR resistance in colorectal cancers

Guoli Chen, Ming-Tseh Lin

Editorials

Into the eye of the storm: breast cancer’s somatic mutation landscape points to DNA damage and repair

Joanne Ngeow, Emily Nizialek, Charis Eng

Perspective

Circular RNAs and competing endogenous RNA (ceRNA) networks

Apratim Mitra, Karl Pfeifer, Ki-Sun Park

The STAMPEDE trial: paradigm-changing data through innovative trial design

Bradley C. Carthon, Emmanuel S. Antonarakis

Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway

Derek B. Oien, Jeremy Chien, Nikki Cheng

Feed your gut with caution!

Vishal Singh, Beng San Yeoh, Matam Vijay-Kumar

Precision oncology: identifying predictive biomarkers for the treatment of metastatic renal cell carcinoma

Parth K. Modi, Nicholas J. Farber, Eric A. Singer

Letter to the Editors

Multiscale modeling of glioblastoma

Huaming Yan, Mónica Romero-López, Lesly I. Benitez, Kaijun Di, Hermann B. Frieboes, Christopher C. W. Hughes, Daniela A. Bota, John S. Lowengrub

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients

Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Review Articles

New developments in treatment planning and verification of particle beam therapy

Reinhard W. Schulte, Andrew J. Wroe

Externally modulated theranostic nanoparticles

Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi

Intestinal stem cell injury and protection during cancer therapy

Jian Yu

Cancer stem cells in glioma: challenges and opportunities

Jialiang Wang, Yufang Ma, Michael K. Cooper

Tumor microenvironment and nanotherapeutics

Meenakshi Upreti, Amar Jyoti, Pallavi Sethi

Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury

Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis

Chang-Lung Lee, Jordan M. Blum, David G. Kirsch

DNA ligases as therapeutic targets

Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest

DNA damage tolerance: a double-edged sword guarding the genome

Gargi Ghosal, Junjie Chen

DNA double strand break repair via non-homologous end-joining

Anthony J. Davis, David J. Chen

DNA crosslinking damage and cancer - a tale of friend and foe

Yaling Huang, Lei Li

Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation

Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan

MDM2 and MDMX: alone and together in regulation of p53

Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan

Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase

Lijian Shao, Lixian Wu, Daohong Zhou

Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment

Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen

SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis

Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos

Normal tissue protection for improving radiotherapy: where are the Gaps?

Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman

Improving chemoradiotherapy with nanoparticle therapeutics

Michael Joseph Eblan, Andrew Zhuang Wang

Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization

Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn

Molecular mechanisms involved in tumor repopulation after radiotherapy

Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li

Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules

Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy

Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar

Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma

Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

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Translational Cancer Research is an international, open access, peer-reviewed journal indexed in Scopus and Science Citation Index Expanded (SCIE), focusing on original, science-based researches on clinical, basic and translational aspects. It publishes laboratory studies of novel therapeutic interventions, clinical trials which evaluate new treatment paradigms for cancer, results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of cancer patients and etc.